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Hematology&Oncology
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Immunosuppression study helps understand why some prostate cancer treatments do not work as expected

Immunosuppression study helps understand why some prostate cancer treatments do not work as expected

byTampere UniversityOn the left is a tissue sample from the prostate stained with hematoxylin and eosin. Hematoxylin stains the nuclei blue or purple because it binds to DNA, and eosin stains th

Immunosuppression study helps understand why some prostate cancer treatments do not work as expected

byTampere UniversityOn the left is a tissue sample from the prostate stained with hematoxylin and eosin. Hematoxylin stains the nuclei blue or purple because it binds to DNA, and eosin stains th
Anticancer drugs could make immunotherapies more effective

Anticancer drugs could make immunotherapies more effective

byWeill Cornell Medical CollegePretreatment with EZH2 inhibitor (top right) leads to higher recruitment of CAR-T cells (red) into the lymph node tumor compared with control (top left). Pretreatm

Anticancer drugs could make immunotherapies more effective

byWeill Cornell Medical CollegePretreatment with EZH2 inhibitor (top right) leads to higher recruitment of CAR-T cells (red) into the lymph node tumor compared with control (top left). Pretreatm
Neurocognitive battery feasible in 3-year-olds during leukemia treatment

Neurocognitive battery feasible in 3-year-olds during leukemia treatment

by Elana GotkineA brief neurocognitive battery is feasible for use in 3-year-olds during acute lymphoblastic leukemia treatment, according to a studypublishedonline Dec. 9 inPediatri

Neurocognitive battery feasible in 3-year-olds during leukemia treatment

by Elana GotkineA brief neurocognitive battery is feasible for use in 3-year-olds during acute lymphoblastic leukemia treatment, according to a studypublishedonline Dec. 9 inPediatri
Could a pill replace gene therapy for sickle cell disease? Research uncovers potential path to small-molecule drug

Could a pill replace gene therapy for sickle cell disease? Research uncovers potential path to small-molecule drug

by Nancy Fliesler,Children's Hospital BostonNew work suggests ways to target the BCL11A protein with drugs, enabling patients with sickle cell disease to produce non-sickling fetal hemoglobi

Could a pill replace gene therapy for sickle cell disease? Research uncovers potential path to small-molecule drug

by Nancy Fliesler,Children's Hospital BostonNew work suggests ways to target the BCL11A protein with drugs, enabling patients with sickle cell disease to produce non-sickling fetal hemoglobi
Adding polyvinyl alcohol to a boron-containing drug leads to strong antitumor activity in head and neck cancers

Adding polyvinyl alcohol to a boron-containing drug leads to strong antitumor activity in head and neck cancers

byUniversity of TokyoCancer cell during cell division. Credit: National Institutes of HealthTreatment for more advanced and difficult-to-treat head and neck cancers can be improved with the addi

Adding polyvinyl alcohol to a boron-containing drug leads to strong antitumor activity in head and neck cancers

byUniversity of TokyoCancer cell during cell division. Credit: National Institutes of HealthTreatment for more advanced and difficult-to-treat head and neck cancers can be improved with the addi
Cell-based immunotherapy shows promise in early clinical trial for breast cancer

Cell-based immunotherapy shows promise in early clinical trial for breast cancer

byKent State UniversityBreast imaging of one trial patient before (left image) and after (right image) six weeks of experimental immunotherapy. Note diminution of area of disease (dense white ar

Cell-based immunotherapy shows promise in early clinical trial for breast cancer

byKent State UniversityBreast imaging of one trial patient before (left image) and after (right image) six weeks of experimental immunotherapy. Note diminution of area of disease (dense white ar
How individual mutations of the tumor suppressor p53 affect pancreatic carcinomas

How individual mutations of the tumor suppressor p53 affect pancreatic carcinomas

byUniversity of KonstanzMetabolic profile of p53 mutant variants in pancreatic cancer. Credit:Journal of Experimental & Clinical Cancer Research(2024). DOI: 10.1186/s13046-024-03

How individual mutations of the tumor suppressor p53 affect pancreatic carcinomas

byUniversity of KonstanzMetabolic profile of p53 mutant variants in pancreatic cancer. Credit:Journal of Experimental & Clinical Cancer Research(2024). DOI: 10.1186/s13046-024-03
Cancer risk declines in old age: New research helps explain why

Cancer risk declines in old age: New research helps explain why

by Ian Demsky,Memorial Sloan Kettering Cancer CenterAged AT2 cells exhibit reduced cell-intrinsic potential for regeneration and tumorigenesis. Credit:Nature(2024). DOI: 10.1038/s415

Cancer risk declines in old age: New research helps explain why

by Ian Demsky,Memorial Sloan Kettering Cancer CenterAged AT2 cells exhibit reduced cell-intrinsic potential for regeneration and tumorigenesis. Credit:Nature(2024). DOI: 10.1038/s415
Abnormal prenatal blood test results could indicate hidden maternal cancers

Abnormal prenatal blood test results could indicate hidden maternal cancers

byNIH/Eunice Kennedy Shriver National Institute of Child Health and Human DevelopmentCredit: Josh Willink from PexelsResearchers at the National Institutes of Health (NIH) found previously undet

Abnormal prenatal blood test results could indicate hidden maternal cancers

byNIH/Eunice Kennedy Shriver National Institute of Child Health and Human DevelopmentCredit: Josh Willink from PexelsResearchers at the National Institutes of Health (NIH) found previously undet