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Allergy&Clinical immunology
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Retraining the immune system to treat type 1 diabetes

Retraining the immune system to treat type 1 diabetes

byUniversity of MissouriCredit:JCI Insight(2026). DOI: 10.1172/jci.insight.200686Type 1 diabetes (T1D) is a lifelong autoimmune disorder where the immune system attacks islets, certain areas of the pa

Retraining the immune system to treat type 1 diabetes

byUniversity of MissouriCredit:JCI Insight(2026). DOI: 10.1172/jci.insight.200686Type 1 diabetes (T1D) is a lifelong autoimmune disorder where the immune system attacks islets, certain areas of the pa
How cells clear immune signals could reshape drug design and cancer spread research

How cells clear immune signals could reshape drug design and cancer spread research

byUniversity of KonstanzCredit: Unsplash/CC0 Public DomainOur body receives and processes a vast number of signals. Chemical signals serve as guidance cues and ensure, for example, that immune cells a

How cells clear immune signals could reshape drug design and cancer spread research

byUniversity of KonstanzCredit: Unsplash/CC0 Public DomainOur body receives and processes a vast number of signals. Chemical signals serve as guidance cues and ensure, for example, that immune cells a
How cells fight infection from the inside: Newly identified ADX pathway may broaden understanding of immunity

How cells fight infection from the inside: Newly identified ADX pathway may broaden understanding of immunity

byCell PressSuper-resolution image of an LC3-positive autophagosome engulfing a TRIM21- and antibody-coated adenovirus. Credit: Claudia Puri, Matthew J. Gratian, Anna Albecka, and Tyler Rhinesmith.Whe

How cells fight infection from the inside: Newly identified ADX pathway may broaden understanding of immunity

byCell PressSuper-resolution image of an LC3-positive autophagosome engulfing a TRIM21- and antibody-coated adenovirus. Credit: Claudia Puri, Matthew J. Gratian, Anna Albecka, and Tyler Rhinesmith.Whe
Early immunotherapy aids in treating potentially fatal fungal pneumonias in preclinical models

Early immunotherapy aids in treating potentially fatal fungal pneumonias in preclinical models

byUniversity of Texas MD Anderson Cancer CenterHematoxylin & eosin-stained lung tissue sections according to the treatment arm, showing an absence of lymphocytic infiltrates, even in mice that rec

Early immunotherapy aids in treating potentially fatal fungal pneumonias in preclinical models

byUniversity of Texas MD Anderson Cancer CenterHematoxylin & eosin-stained lung tissue sections according to the treatment arm, showing an absence of lymphocytic infiltrates, even in mice that rec
New drug cuts relapse risk by half in rare immune disorder trial

New drug cuts relapse risk by half in rare immune disorder trial

by Sarah Williams,Stanford UniversityIn IgG4-related disease, B cells (above) attack the body's own tissue. A study led by Stanford Medicine has found that a drug reduces the chance of relapse. Cr

New drug cuts relapse risk by half in rare immune disorder trial

by Sarah Williams,Stanford UniversityIn IgG4-related disease, B cells (above) attack the body's own tissue. A study led by Stanford Medicine has found that a drug reduces the chance of relapse. Cr
Macrophages in 'marathon mode' may drive skin granulomas, pointing to new therapies

Macrophages in 'marathon mode' may drive skin granulomas, pointing to new therapies

by Uta von der Gönna, Jena UniversityCredit:Science Advances(2026). DOI: 10.1126/sciadv.aea0773An international research team has succeeded in elucidating key immunological and biochemical mechanisms

Macrophages in 'marathon mode' may drive skin granulomas, pointing to new therapies

by Uta von der Gönna, Jena UniversityCredit:Science Advances(2026). DOI: 10.1126/sciadv.aea0773An international research team has succeeded in elucidating key immunological and biochemical mechanisms
T cells may be key to stopping measles virus—and its deadly relatives

T cells may be key to stopping measles virus—and its deadly relatives

byLa Jolla Institute for ImmunologyCredit: Unsplash/CC0 Public DomainT cells are some of the immune system's most important warriors. They can stop tumor growth and even fight off severe infection

T cells may be key to stopping measles virus—and its deadly relatives

byLa Jolla Institute for ImmunologyCredit: Unsplash/CC0 Public DomainT cells are some of the immune system's most important warriors. They can stop tumor growth and even fight off severe infection
Stopping tick spit: What a new saliva control map could mean for Lyme prevention

Stopping tick spit: What a new saliva control map could mean for Lyme prevention

byINRAETicks are major vectors of infectious diseases, affecting both animals and humans. Their ability to remain attached to a host and feed on their blood over the course of several days derives fro

Stopping tick spit: What a new saliva control map could mean for Lyme prevention

byINRAETicks are major vectors of infectious diseases, affecting both animals and humans. Their ability to remain attached to a host and feed on their blood over the course of several days derives fro
How some autoantibodies contribute to clots: The C4BP link and a path to treatment

How some autoantibodies contribute to clots: The C4BP link and a path to treatment

by Olivia Dimmer,Northwestern UniversityCredit: Pixabay/CC0 Public DomainNorthwestern Medicine investigators have uncovered a missing link behind the harmful effects of autoantibodies linked to blood

How some autoantibodies contribute to clots: The C4BP link and a path to treatment

by Olivia Dimmer,Northwestern UniversityCredit: Pixabay/CC0 Public DomainNorthwestern Medicine investigators have uncovered a missing link behind the harmful effects of autoantibodies linked to blood
How bacteria outsmart the immune system: Two-pronged strategy revealed

How bacteria outsmart the immune system: Two-pronged strategy revealed

byHebrew University of JerusalemModel of the NleD-PPM1A complex. Credit:Advanced Science(2026). DOI: 10.1002/advs.202509702Researchers have uncovered how a disease-causing bacterium uses a single prot

How bacteria outsmart the immune system: Two-pronged strategy revealed

byHebrew University of JerusalemModel of the NleD-PPM1A complex. Credit:Advanced Science(2026). DOI: 10.1002/advs.202509702Researchers have uncovered how a disease-causing bacterium uses a single prot