Why some cancer therapies don't work for all patients: A tumor backup survival pathway

by Anne Trafton,Massachusetts Institute of TechnologyMany of the targeted tumors turn on a backup survival pathway that helps them keep growing when tyrosine kinase—pictured here as strands—is turned

Updated on: May 26,2026

Why some cancer therapies don't work for all patients: A tumor backup survival pathway

by Anne Trafton,Massachusetts Institute of TechnologyMany of the targeted tumors turn on a backup survival pathway that helps them keep growing when tyrosine kinase—pictured here as strands—is turned

Updated on:May 26,2026

PSMA therapy delays hormone therapy in prostate cancer, clinical trial finds

byRadboud UniversityNuclear medicine physician James Nagarajah from Radboudumc in the clinics. Credit: RadboudumcWhere previous research showed that PSMA therapy for prostate cancer can prolong the li

Updated on: May 25,2026

PSMA therapy delays hormone therapy in prostate cancer, clinical trial finds

byRadboud UniversityNuclear medicine physician James Nagarajah from Radboudumc in the clinics. Credit: RadboudumcWhere previous research showed that PSMA therapy for prostate cancer can prolong the li

Updated on:May 25,2026

An avatar to study pediatric brain cancer may soon be a reality

byUniversity of TrentoA summary of pPDT and pPDXT generation, amplification and biobanking and their use in drug screening and other applications. Credit:Nature Protocols(2026). DOI: 10.1038/s41596-02

Updated on: May 22,2026

An avatar to study pediatric brain cancer may soon be a reality

byUniversity of TrentoA summary of pPDT and pPDXT generation, amplification and biobanking and their use in drug screening and other applications. Credit:Nature Protocols(2026). DOI: 10.1038/s41596-02

Updated on:May 22,2026

A new immunotherapy target? How SRC-3 in Tregs may reshape solid-tumor treatment

by Ana María Rodríguez,Baylor College of MedicineThe loss of SRC-3 in Treg leads to immune suppression of glioblastoma in mice: (A) Experimental design for the orthotopic injection of glioblastoma cel

Updated on: May 23,2026

A new immunotherapy target? How SRC-3 in Tregs may reshape solid-tumor treatment

by Ana María Rodríguez,Baylor College of MedicineThe loss of SRC-3 in Treg leads to immune suppression of glioblastoma in mice: (A) Experimental design for the orthotopic injection of glioblastoma cel

Updated on:May 23,2026

Genetic variants involved in rapid immune response linked to earlier breast cancer onset in BRCA1 carriers

byBritish Medical JournalCredit: CC0 Public DomainDamaging variants in genes involved in a rapid immune response (innate immunity) are significantly linked to earlier breast cancer onset in carriers o

Updated on: May 24,2026

Genetic variants involved in rapid immune response linked to earlier breast cancer onset in BRCA1 carriers

byBritish Medical JournalCredit: CC0 Public DomainDamaging variants in genes involved in a rapid immune response (innate immunity) are significantly linked to earlier breast cancer onset in carriers o

Updated on:May 24,2026

After allogeneic transplant, VIC-1911 regimen shows low severe GVHD and no relapse

byRoswell Park Comprehensive Cancer CenterCredit: Unsplash/CC0 Public DomainResults of a Phase I clinical trial show that patients who undergo a blood stem cell transplant involving a donor have a low

Updated on: May 19,2026

After allogeneic transplant, VIC-1911 regimen shows low severe GVHD and no relapse

byRoswell Park Comprehensive Cancer CenterCredit: Unsplash/CC0 Public DomainResults of a Phase I clinical trial show that patients who undergo a blood stem cell transplant involving a donor have a low

Updated on:May 19,2026

TYK2 protein suppresses breast cancer metastasis by sensing extracellular stiffness, research finds

by Miles Martin,University of California - San DiegoIn healthy tissues, seen in the top two panels here, TYK2 (green) is found on the cell membrane and colocalizes with E-cadherin (red), a protein tha

Updated on: May 19,2026

TYK2 protein suppresses breast cancer metastasis by sensing extracellular stiffness, research finds

by Miles Martin,University of California - San DiegoIn healthy tissues, seen in the top two panels here, TYK2 (green) is found on the cell membrane and colocalizes with E-cadherin (red), a protein tha

Updated on:May 19,2026

uPAR-targeted CAR T cells shrank solid tumors and cleared metastases in mice

byMemorial Sloan Kettering Cancer CenterCredit:Cell(2026). DOI: 10.1016/j.cell.2026.03.002Chimeric antigen receptor T-cell therapy—CAR T for short—has been a major advance in treating blood cancers li

Updated on: May 20,2026

uPAR-targeted CAR T cells shrank solid tumors and cleared metastases in mice

byMemorial Sloan Kettering Cancer CenterCredit:Cell(2026). DOI: 10.1016/j.cell.2026.03.002Chimeric antigen receptor T-cell therapy—CAR T for short—has been a major advance in treating blood cancers li

Updated on:May 20,2026

New analytical method reveals how drug combinations act in leukemia

byTampere UniversityCoPISA workflow and possible states for target discovery in combinatorial therapy. Credit:Nature Communications(2026). DOI: 10.1038/s41467-026-70394-3Acute myeloid leukemia (AML) r

Updated on: May 15,2026

New analytical method reveals how drug combinations act in leukemia

byTampere UniversityCoPISA workflow and possible states for target discovery in combinatorial therapy. Credit:Nature Communications(2026). DOI: 10.1038/s41467-026-70394-3Acute myeloid leukemia (AML) r

Updated on:May 15,2026

FDA warns biotech firm over cancer drug claims

by HealthDay StaffThe U.S. Food and Drug Administration (FDA) has warned a biotech company about claims that its bladder cancer drug could treat and prevent multiple types of cancer.The agency sent a

Updated on: April 22,2026

FDA warns biotech firm over cancer drug claims

by HealthDay StaffThe U.S. Food and Drug Administration (FDA) has warned a biotech company about claims that its bladder cancer drug could treat and prevent multiple types of cancer.The agency sent a

Updated on:April 22,2026

MetaRing quickly identifies breast cancer drug sensitivity

by Hefei Institutes of Physical Science, Chinese Academy of SciencesSchematic illustration of the MetaRing platform for detecting paclitaxel treatment sensitivity in breast cancer. Credit: HUANG Guang

Updated on: April 27,2026

MetaRing quickly identifies breast cancer drug sensitivity

by Hefei Institutes of Physical Science, Chinese Academy of SciencesSchematic illustration of the MetaRing platform for detecting paclitaxel treatment sensitivity in breast cancer. Credit: HUANG Guang

Updated on:April 27,2026

Rearranging tumor cell structures—new approach could treat cancer

by Tim Tedeschi,University of CincinnatiBiomedical research typically follows a familiar path: developing treatments that block, enhance or mutate certain signaling pathways, genes or proteins to chan

Updated on: March 28,2026

Rearranging tumor cell structures—new approach could treat cancer

by Tim Tedeschi,University of CincinnatiBiomedical research typically follows a familiar path: developing treatments that block, enhance or mutate certain signaling pathways, genes or proteins to chan

Updated on:March 28,2026