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Hematology&Oncology
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Colorectal cancer's immune puzzle cracked: Two Treg cell types shape survival odds

Colorectal cancer's immune puzzle cracked: Two Treg cell types shape survival odds

by Ian Demsky,Memorial Sloan Kettering Cancer CenterCredit: Unsplash/CC0 Public DomainIn most solid tumors, high numbers of regulatory T (Treg) cells are associated with poorer outcomes because they d

Colorectal cancer's immune puzzle cracked: Two Treg cell types shape survival odds

by Ian Demsky,Memorial Sloan Kettering Cancer CenterCredit: Unsplash/CC0 Public DomainIn most solid tumors, high numbers of regulatory T (Treg) cells are associated with poorer outcomes because they d
Cancer messenger substances disrupt muscle function and trigger muscle breakdown

Cancer messenger substances disrupt muscle function and trigger muscle breakdown

by Inka Burow,Hannover Medical SchoolDr Arnab Nayak, private lecturer, investigates the effect of pro-inflammatory messengers on muscle wasting in cancer. Credit: Tim Holler/MHHCancer patients often l

Cancer messenger substances disrupt muscle function and trigger muscle breakdown

by Inka Burow,Hannover Medical SchoolDr Arnab Nayak, private lecturer, investigates the effect of pro-inflammatory messengers on muscle wasting in cancer. Credit: Tim Holler/MHHCancer patients often l
Combination therapy for pancreatic cancer offers new treatment approach

Combination therapy for pancreatic cancer offers new treatment approach

by Lena Bösch,University Medical Center GöttingenMini tumor models from patient-derived tissue, known as organoids, without and with therapy. Bottom: Tumors (blue) with macrophages (yellow)—immune cel

Combination therapy for pancreatic cancer offers new treatment approach

by Lena Bösch,University Medical Center GöttingenMini tumor models from patient-derived tissue, known as organoids, without and with therapy. Bottom: Tumors (blue) with macrophages (yellow)—immune cel
How scientists are hacking bacteria to treat cancer, self-destruct, then vanish without a trace

How scientists are hacking bacteria to treat cancer, self-destruct, then vanish without a trace

by Josephine Wright, Susan Woods,The ConversationCredit: CC0 Public DomainBacteria are rapidly emerging as anew classof "living medicines" used to kill cancer cells.We're still a long wa

How scientists are hacking bacteria to treat cancer, self-destruct, then vanish without a trace

by Josephine Wright, Susan Woods,The ConversationCredit: CC0 Public DomainBacteria are rapidly emerging as anew classof "living medicines" used to kill cancer cells.We're still a long wa
Nanovaccine shows great promise for treating HPV-related cancers

Nanovaccine shows great promise for treating HPV-related cancers

byUTSouthwestern Medical CenterSTING nanovaccine is designed to deliver tumor antigens (Ag) and STING agonists (diABZI, PSC7A) to the tumor and secondary lymphoid organs (SLOs) to activate antit

Nanovaccine shows great promise for treating HPV-related cancers

byUTSouthwestern Medical CenterSTING nanovaccine is designed to deliver tumor antigens (Ag) and STING agonists (diABZI, PSC7A) to the tumor and secondary lymphoid organs (SLOs) to activate antit
Link between tumor metabolism and drug efficacy in cancer cells may help advance precision chemotherapy

Link between tumor metabolism and drug efficacy in cancer cells may help advance precision chemotherapy

byStonyBrookUniversityIntracellular regulation of PRMT5 activity and development of chemical probes CBH-001 and CBH-002. Credit:Nature Communications(2025). DOI: 10.1038/s41467-025-65558-6

Link between tumor metabolism and drug efficacy in cancer cells may help advance precision chemotherapy

byStonyBrookUniversityIntracellular regulation of PRMT5 activity and development of chemical probes CBH-001 and CBH-002. Credit:Nature Communications(2025). DOI: 10.1038/s41467-025-65558-6
New risk score helps predict pancreatic cancer recurrence

New risk score helps predict pancreatic cancer recurrence

byCedars-Sinai Medical CenterAxial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domainCedars-Sinai investigators, leading a multi-institutional team,

New risk score helps predict pancreatic cancer recurrence

byCedars-Sinai Medical CenterAxial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domainCedars-Sinai investigators, leading a multi-institutional team,
Engineered dendritic cells boost cancer immunotherapy

Engineered dendritic cells boost cancer immunotherapy

byEcole Polytechnique Federale de LausanneEngineered dendritic cells (right) acquire tumor-derived extracellular vesicles that contain cancer antigens (left), stimulating anti-tumor immunity. Credit:

Engineered dendritic cells boost cancer immunotherapy

byEcole Polytechnique Federale de LausanneEngineered dendritic cells (right) acquire tumor-derived extracellular vesicles that contain cancer antigens (left), stimulating anti-tumor immunity. Credit:
Global survey highlights challenges faced by young women with advanced breast cancer

Global survey highlights challenges faced by young women with advanced breast cancer

by Associação Advanced Breast Cancer Global AllianceCredit: Unsplash/CC0 Public DomainNearly half of all women aged younger than 40 who live with advanced breast cancer have children under the age of

Global survey highlights challenges faced by young women with advanced breast cancer

by Associação Advanced Breast Cancer Global AllianceCredit: Unsplash/CC0 Public DomainNearly half of all women aged younger than 40 who live with advanced breast cancer have children under the age of
Common medicines may influence CRISPR therapy outcomes and precision cancer treatment

Common medicines may influence CRISPR therapy outcomes and precision cancer treatment

byMax Planck SocietyDrug screening for DSB repair pathway modulators. Credit:Nature Communications(2025). DOI: 10.1038/s41467-025-67243-0In a new study, scientists at the Max Planck Institute for Evol

Common medicines may influence CRISPR therapy outcomes and precision cancer treatment

byMax Planck SocietyDrug screening for DSB repair pathway modulators. Credit:Nature Communications(2025). DOI: 10.1038/s41467-025-67243-0In a new study, scientists at the Max Planck Institute for Evol
How to reduce risk of lymphedema after head and neck cancer

How to reduce risk of lymphedema after head and neck cancer

by Åsa Hansdotter,Lund UniversityCredit:Oral Oncology(2025). DOI: 10.1016/j.oraloncology.2025.107671Lymphedema after head and neck cancer is considerably more common than previously assumed and can pe

How to reduce risk of lymphedema after head and neck cancer

by Åsa Hansdotter,Lund UniversityCredit:Oral Oncology(2025). DOI: 10.1016/j.oraloncology.2025.107671Lymphedema after head and neck cancer is considerably more common than previously assumed and can pe
FDA grants fast track designation to drug combo for colorectal cancer

FDA grants fast track designation to drug combo for colorectal cancer

by April Wilkerson,University of OklahomaCredit: Pixabay/CC0 Public DomainThe U.S. Food and Drug Administration has granted Fast Track Designation to a new drug combination for metastatic colorectal c

FDA grants fast track designation to drug combo for colorectal cancer

by April Wilkerson,University of OklahomaCredit: Pixabay/CC0 Public DomainThe U.S. Food and Drug Administration has granted Fast Track Designation to a new drug combination for metastatic colorectal c