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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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Seeking microscopic clues to beating deadly brain tumors

Seeking microscopic clues to beating deadly brain tumors

by Hackensack Meridian HealthH&E stained sections of patient glioblastoma samples. Higher magnifcation of representative regions are shown in the colored boxes. Histologic features include low (bl

Seeking microscopic clues to beating deadly brain tumors

by Hackensack Meridian HealthH&E stained sections of patient glioblastoma samples. Higher magnifcation of representative regions are shown in the colored boxes. Histologic features include low (bl
Researchers publish preclinical data on new drug combination to treat neuroblastoma

Researchers publish preclinical data on new drug combination to treat neuroblastoma

by Texas Tech UniversityTTUHSC's C. Patrick Reynolds, M.D., Ph.D., recently published preclinical data on a new drug combination to treat neuroblastoma. Credit: TTUHSCNeuroblastoma is the mos

Researchers publish preclinical data on new drug combination to treat neuroblastoma

by Texas Tech UniversityTTUHSC's C. Patrick Reynolds, M.D., Ph.D., recently published preclinical data on a new drug combination to treat neuroblastoma. Credit: TTUHSCNeuroblastoma is the mos
AI predicts cancer patient survival by reading doctor's notes

AI predicts cancer patient survival by reading doctor's notes

byUniversity of British ColumbiaSimplified Diagrams of the Language Models Used in This Work A, The bag-of-words model counts word occurrences in a document, which is then used by a traditional

AI predicts cancer patient survival by reading doctor's notes

byUniversity of British ColumbiaSimplified Diagrams of the Language Models Used in This Work A, The bag-of-words model counts word occurrences in a document, which is then used by a traditional
Researchers report on ctDNA-based detection of residual disease prognostic for resected CRC

Researchers report on ctDNA-based detection of residual disease prognostic for resected CRC

by Elana GotkineFor patients with radically resected, stage II to IV colorectal cancer (CRC), circulating tumor (ct)DNA-based detection of molecular residual disease (MRD) in response to adjuvant chem

Researchers report on ctDNA-based detection of residual disease prognostic for resected CRC

by Elana GotkineFor patients with radically resected, stage II to IV colorectal cancer (CRC), circulating tumor (ct)DNA-based detection of molecular residual disease (MRD) in response to adjuvant chem
New AI-based biomarker can help predict immunotherapy response for patients with lung cancer

New AI-based biomarker can help predict immunotherapy response for patients with lung cancer

byEmory UniversityResponder tumor to ICI has less tortuous vessel branches compared to nonresponder. (A and B) CT scans of a responder and nonresponder to IO with corresponding 3D rendering of t

New AI-based biomarker can help predict immunotherapy response for patients with lung cancer

byEmory UniversityResponder tumor to ICI has less tortuous vessel branches compared to nonresponder. (A and B) CT scans of a responder and nonresponder to IO with corresponding 3D rendering of t
Therapeutic and diagnostic functions of one antibody for pancreatic cancer

Therapeutic and diagnostic functions of one antibody for pancreatic cancer

by Osaka UniversityFig.1: DKK1–CKAP4 signaling and application of the anti-CKAP4 antibody. DKK1 and CKAP4 are overexpressed in cancer cells and the PI3 kinase–AKT pathway is activated, promoting

Therapeutic and diagnostic functions of one antibody for pancreatic cancer

by Osaka UniversityFig.1: DKK1–CKAP4 signaling and application of the anti-CKAP4 antibody. DKK1 and CKAP4 are overexpressed in cancer cells and the PI3 kinase–AKT pathway is activated, promoting
Test can predict how people with leukaemia will respond to chemotherapy

Test can predict how people with leukaemia will respond to chemotherapy

by BloodwiseCredit: CC0 Public DomainThe first test to quickly and accurately predict how people will respond to standard treatment for the most common type of leukaemia has been developed at Cardiff

Test can predict how people with leukaemia will respond to chemotherapy

by BloodwiseCredit: CC0 Public DomainThe first test to quickly and accurately predict how people will respond to standard treatment for the most common type of leukaemia has been developed at Cardiff
New prostate cancer diagnostic pathway paves way for general screening

New prostate cancer diagnostic pathway paves way for general screening

bySwedish Research CouncilCredit: Pixabay/CC0 Public DomainIn screening for prostate cancer, the risk of overdiagnosis can be halved, a University of Gothenburg study shows. With the proposed di

New prostate cancer diagnostic pathway paves way for general screening

bySwedish Research CouncilCredit: Pixabay/CC0 Public DomainIn screening for prostate cancer, the risk of overdiagnosis can be halved, a University of Gothenburg study shows. With the proposed di
Advanced melanoma survival improves significantly when immunotherapy is given before targeted therapy

Advanced melanoma survival improves significantly when immunotherapy is given before targeted therapy

by Georgetown University Medical CenterCredit: Pixabay/CC0 Public DomainA clinical trial led by clinicians at Georgetown Lombardi Comprehensive Cancer Center showed a remarkable 20 percent advant

Advanced melanoma survival improves significantly when immunotherapy is given before targeted therapy

by Georgetown University Medical CenterCredit: Pixabay/CC0 Public DomainA clinical trial led by clinicians at Georgetown Lombardi Comprehensive Cancer Center showed a remarkable 20 percent advant
Enhanced cancer immunotherapies through cytokine-labeled T cells

Enhanced cancer immunotherapies through cytokine-labeled T cells

by Benjamin Boettner,Harvard UniversityCredit: CC0 Public DomainThe recent years have seen a wave of adoptive cell therapies (ACTs), a type of immunotherapy in which T cells (T cell transfer the

Enhanced cancer immunotherapies through cytokine-labeled T cells

by Benjamin Boettner,Harvard UniversityCredit: CC0 Public DomainThe recent years have seen a wave of adoptive cell therapies (ACTs), a type of immunotherapy in which T cells (T cell transfer the
Researchers use a new approach to hit an 'undruggable' target

Researchers use a new approach to hit an 'undruggable' target

by University of MichiganGraphical abstract. Credit:Nature Chemical Biology(2023). DOI: 10.1038/s41589-022-01248-4The protein STAT5 has long been an appealing target against cancer, b

Researchers use a new approach to hit an 'undruggable' target

by University of MichiganGraphical abstract. Credit:Nature Chemical Biology(2023). DOI: 10.1038/s41589-022-01248-4The protein STAT5 has long been an appealing target against cancer, b
An unexpected developmental hierarchy in an unusual disease

An unexpected developmental hierarchy in an unusual disease

by CeMM Research Center for Molecular Medicine of the Austrian Academy of SciencesLCH cells from a tumour biopsy, imaged with a confocal microscope. The green staining identifies the actively prolifer

An unexpected developmental hierarchy in an unusual disease

by CeMM Research Center for Molecular Medicine of the Austrian Academy of SciencesLCH cells from a tumour biopsy, imaged with a confocal microscope. The green staining identifies the actively prolifer