Epigenetic mechanism associated with clinical outcome and therapeutic vulnerability in liver cancer

by Josep Carreras Leukaemia Research InstituteNSUN7 epigenetic loss occurs in human primary HCC tumors in association with worse clinical outcome. (A) Percentage of NSUN7 methylation in the TCGA

Updated on: February 18,2024

Epigenetic mechanism associated with clinical outcome and therapeutic vulnerability in liver cancer

by Josep Carreras Leukaemia Research InstituteNSUN7 epigenetic loss occurs in human primary HCC tumors in association with worse clinical outcome. (A) Percentage of NSUN7 methylation in the TCGA

Updated on:February 18,2024

Researchers show how a tumor cell's location and environment affect its identity

by National Institutes of HealthDifferences in cell layers' fluorescent-dye uptake in a model of high-grade serous ovarian cancer. Credit: David B. Morse.Using 3D models of ovarian cancer tum

Updated on: January 30,2024

Researchers show how a tumor cell's location and environment affect its identity

by National Institutes of HealthDifferences in cell layers' fluorescent-dye uptake in a model of high-grade serous ovarian cancer. Credit: David B. Morse.Using 3D models of ovarian cancer tum

Updated on:January 30,2024

Combined epigenetic and immunotherapy for blastic and classical mantle cell lymphoma

by Impact JournalsMechanisms of SCR resistance and characterization of the CD20 negative MCL cell lines 353. Credit: LeBlanc et al,Oncotarget(2022). DOI: 10.18632/oncotarget.28258A new res

Updated on: January 02,2024

Combined epigenetic and immunotherapy for blastic and classical mantle cell lymphoma

by Impact JournalsMechanisms of SCR resistance and characterization of the CD20 negative MCL cell lines 353. Credit: LeBlanc et al,Oncotarget(2022). DOI: 10.18632/oncotarget.28258A new res

Updated on:January 02,2024

Sugar molecules as a target in cancer therapy

byUniversity of BaselTherapeutic desialylation repolarizes tumor-associated macrophages (TAMs). (A) Pathway enrichment analysis performed on all macrophages between treatment conditions. UT, unt

Updated on: January 07,2024

Sugar molecules as a target in cancer therapy

byUniversity of BaselTherapeutic desialylation repolarizes tumor-associated macrophages (TAMs). (A) Pathway enrichment analysis performed on all macrophages between treatment conditions. UT, unt

Updated on:January 07,2024

Why a promising breast cancer drug doesn't work—and how to improve it

by Katherine Fenz,Rockefeller UniversityER-mediated transcriptional resistance to BD inhibition. Credit:Nature Structural & Molecular Biology(2024). DOI: 10.1038/s41594-024-01384

Updated on: September 28,2024

Why a promising breast cancer drug doesn't work—and how to improve it

by Katherine Fenz,Rockefeller UniversityER-mediated transcriptional resistance to BD inhibition. Credit:Nature Structural & Molecular Biology(2024). DOI: 10.1038/s41594-024-01384

Updated on:September 28,2024

More cancers are diagnosed at an advanced stage if patients already have type 2 diabetes, study finds

by European Organisation for Research and Treatment of CancerCredit: CC0 Public DomainA study of 11,945 people in six European countries has shown that people with type 2 diabetes who develop cancer a

Updated on: January 23,2024

More cancers are diagnosed at an advanced stage if patients already have type 2 diabetes, study finds

by European Organisation for Research and Treatment of CancerCredit: CC0 Public DomainA study of 11,945 people in six European countries has shown that people with type 2 diabetes who develop cancer a

Updated on:January 23,2024

Head and neck cancer researchers demonstrate the capability of a deep learning algorithm in the post-surgery setting

by ECOG-ACRIN Cancer Research Group"This type of research is key since it can help identify patients with high-risk, aggressive head and neck cancer, and also help select appropriate patients for

Updated on: January 07,2024

Head and neck cancer researchers demonstrate the capability of a deep learning algorithm in the post-surgery setting

by ECOG-ACRIN Cancer Research Group"This type of research is key since it can help identify patients with high-risk, aggressive head and neck cancer, and also help select appropriate patients for

Updated on:January 07,2024

Newly identified personalized immunotherapy combination treats an aggressive form of advanced prostate cancer

byUniversity of Chicago Medical CenterCredit: Unsplash/CC0 Public DomainImmunotherapies have been successful in treating many cancer conditions; however, not much success has yet been achieved i

Updated on: January 13,2024

Newly identified personalized immunotherapy combination treats an aggressive form of advanced prostate cancer

byUniversity of Chicago Medical CenterCredit: Unsplash/CC0 Public DomainImmunotherapies have been successful in treating many cancer conditions; however, not much success has yet been achieved i

Updated on:January 13,2024

In high-risk neuroblastoma, two stem cell transplants may be better than one

by Nancy Fliesler,Children's Hospital BostonCredit: Children's Hospital BostonSince the early 1990s, chemotherapy followed by an autologous stem cell transplant has been the standard of

Updated on: March 09,2024

In high-risk neuroblastoma, two stem cell transplants may be better than one

by Nancy Fliesler,Children's Hospital BostonCredit: Children's Hospital BostonSince the early 1990s, chemotherapy followed by an autologous stem cell transplant has been the standard of

Updated on:March 09,2024

Researchers discover the Achilles' heel of an aggressive brain cancer

by University of HelsinkiGlioblastoma cells (red) are known to invade the brain (blue). Figure shows patient-derived glioblastoma in murine brain treated with saline (control). Credit: Laakkonen

Updated on: June 22,2024

Researchers discover the Achilles' heel of an aggressive brain cancer

by University of HelsinkiGlioblastoma cells (red) are known to invade the brain (blue). Figure shows patient-derived glioblastoma in murine brain treated with saline (control). Credit: Laakkonen

Updated on:June 22,2024

Researchers develop a study model for Ewing sarcoma in the Drosophila fly

by Institute for Research in Biomedicine (IRB Barcelona)EWS-FLI1FSinduces epithelial malignant tumors in the developing wing discs. Wing imaginal disc from a wild-type third instar larvae (

Updated on: February 20,2024

Researchers develop a study model for Ewing sarcoma in the Drosophila fly

by Institute for Research in Biomedicine (IRB Barcelona)EWS-FLI1FSinduces epithelial malignant tumors in the developing wing discs. Wing imaginal disc from a wild-type third instar larvae (

Updated on:February 20,2024

The rising burden of respiratory tract cancer in Asia

by Cactus CommunicationsTrends in age-standardized rates of TBL cancer, 1990–2019. Deaths for males, females, and both sexes combined; DALYs for males, females, and both sexes combined; and incidence

Updated on: April 06,2024

The rising burden of respiratory tract cancer in Asia

by Cactus CommunicationsTrends in age-standardized rates of TBL cancer, 1990–2019. Deaths for males, females, and both sexes combined; DALYs for males, females, and both sexes combined; and incidence

Updated on:April 06,2024