Telisotuzumab vedotin shows durable response in some Asian patients with nonsquamous NSCLC

by International Association for the Study of Lung CancerCredit: Pixabay/CC0 Public DomainThe c-Met-directed antibody-drug conjugate telisotuzumab vedotin demonstrated durable responses and an accepta

Updated on: September 27,2024

Telisotuzumab vedotin shows durable response in some Asian patients with nonsquamous NSCLC

by International Association for the Study of Lung CancerCredit: Pixabay/CC0 Public DomainThe c-Met-directed antibody-drug conjugate telisotuzumab vedotin demonstrated durable responses and an accepta

Updated on:September 27,2024

Molecular profiling may improve meningioma decision making

by Melissa Rohman,Northwestern UniversityPropensity score matched analysis of degrees of surgical resection in meningioma. Credit:Nature Medicine(2024). DOI: 10.1038/s41591-024-03167

Updated on: September 28,2024

Molecular profiling may improve meningioma decision making

by Melissa Rohman,Northwestern UniversityPropensity score matched analysis of degrees of surgical resection in meningioma. Credit:Nature Medicine(2024). DOI: 10.1038/s41591-024-03167

Updated on:September 28,2024

New biomarker for early prediction of response to CAR-T cell therapy

by Medical University of ViennaCredit: AI-generated imageA MedUni Vienna research team has discovered a highly potent biomarker for clinical response to CAR-T cell therapy, describing the prerequ

Updated on: February 01,2024

New biomarker for early prediction of response to CAR-T cell therapy

by Medical University of ViennaCredit: AI-generated imageA MedUni Vienna research team has discovered a highly potent biomarker for clinical response to CAR-T cell therapy, describing the prerequ

Updated on:February 01,2024

Major progress in curing brain tumors by blocking certain functions in cells with a docked molecule

by University of GothenburgThe researchers’ molecule Z4P inhibits one of the mechanisms that regulate protein production in a cancer cell. This inhibition causes the cancer cell to die. Three pic

Updated on: February 18,2024

Major progress in curing brain tumors by blocking certain functions in cells with a docked molecule

by University of GothenburgThe researchers’ molecule Z4P inhibits one of the mechanisms that regulate protein production in a cancer cell. This inhibition causes the cancer cell to die. Three pic

Updated on:February 18,2024

Bioengineered antibodies target mutant HER2 proteins

byNYU Langone HealthCredit: Unsplash/CC0 Public DomainFor some proteins, a single mutation, or change in its DNA instructions, is all it takes to tip the balance between functioning normally and

Updated on: November 10,2024

Bioengineered antibodies target mutant HER2 proteins

byNYU Langone HealthCredit: Unsplash/CC0 Public DomainFor some proteins, a single mutation, or change in its DNA instructions, is all it takes to tip the balance between functioning normally and

Updated on:November 10,2024

Researchers discover a new cancer-driving mutation in 'dark matter' of the cancer genome

by Ontario Institute for Cancer ResearchCredit: CC0 Public DomainAn Ontario-led research group has discovered a novel cancer-driving mutation in the vast non-coding regions of the human cancer genome,

Updated on: June 04,2024

Researchers discover a new cancer-driving mutation in 'dark matter' of the cancer genome

by Ontario Institute for Cancer ResearchCredit: CC0 Public DomainAn Ontario-led research group has discovered a novel cancer-driving mutation in the vast non-coding regions of the human cancer genome,

Updated on:June 04,2024

Study suggests a way to re-energize tired T cells when treating cancer, viral infections

by Ohio State University Medical CenterScanning electron micrograph of a human T lymphocyte (also called a T cell) from the immune system of a healthy donor. Credit: NIAIDA new study by researche

Updated on: February 20,2024

Study suggests a way to re-energize tired T cells when treating cancer, viral infections

by Ohio State University Medical CenterScanning electron micrograph of a human T lymphocyte (also called a T cell) from the immune system of a healthy donor. Credit: NIAIDA new study by researche

Updated on:February 20,2024

New AI-based biomarker can help predict immunotherapy response for patients with lung cancer

byEmory UniversityResponder tumor to ICI has less tortuous vessel branches compared to nonresponder. (A and B) CT scans of a responder and nonresponder to IO with corresponding 3D rendering of t

Updated on: January 12,2024

New AI-based biomarker can help predict immunotherapy response for patients with lung cancer

byEmory UniversityResponder tumor to ICI has less tortuous vessel branches compared to nonresponder. (A and B) CT scans of a responder and nonresponder to IO with corresponding 3D rendering of t

Updated on:January 12,2024

Genetically modified virus shown able to kill tumors in mice with retinoblastoma

by Bob Yirka , Medical XpressThe virus-based anticancer therapy (VCN-01) showed toxic effects against retinoblastoma cells after 12 days. Credit: G. Pascual-Pasto et al.,Science Translational Me

Updated on: April 01,2024

Genetically modified virus shown able to kill tumors in mice with retinoblastoma

by Bob Yirka , Medical XpressThe virus-based anticancer therapy (VCN-01) showed toxic effects against retinoblastoma cells after 12 days. Credit: G. Pascual-Pasto et al.,Science Translational Me

Updated on:April 01,2024

Epigenetic mechanism associated with clinical outcome and therapeutic vulnerability in liver cancer

by Josep Carreras Leukaemia Research InstituteNSUN7 epigenetic loss occurs in human primary HCC tumors in association with worse clinical outcome. (A) Percentage of NSUN7 methylation in the TCGA

Updated on: February 18,2024

Epigenetic mechanism associated with clinical outcome and therapeutic vulnerability in liver cancer

by Josep Carreras Leukaemia Research InstituteNSUN7 epigenetic loss occurs in human primary HCC tumors in association with worse clinical outcome. (A) Percentage of NSUN7 methylation in the TCGA

Updated on:February 18,2024

Scientists target glioma cancer stem cells, which could improve patient survival

by Dartmouth-Hitchcock Medical CenterThis photo illustrates the effect of secretion inhibitors on the growth of high-grade glial tumors in mice. The top row show tumors grown in the absence of se

Updated on: March 06,2024

Scientists target glioma cancer stem cells, which could improve patient survival

by Dartmouth-Hitchcock Medical CenterThis photo illustrates the effect of secretion inhibitors on the growth of high-grade glial tumors in mice. The top row show tumors grown in the absence of se

Updated on:March 06,2024

Solving the mystery of NPM1 in acute myeloid leukemia

by Allison Mickey,Baylor College of MedicineDr. Margaret Goodell, the corresponding author of this work. Credit: Baylor College of MedicineAlthough it has long been recognized that mutations of

Updated on: March 12,2024

Solving the mystery of NPM1 in acute myeloid leukemia

by Allison Mickey,Baylor College of MedicineDr. Margaret Goodell, the corresponding author of this work. Credit: Baylor College of MedicineAlthough it has long been recognized that mutations of

Updated on:March 12,2024