Lost metabolic fitness of CAR NK cells is key mechanism of tumor resistance, study discovers

byUniversity of Texas M. D. Anderson Cancer CenterCAR-NK cells have a distinct single-cell transcriptome and metabolic profile. Credit:Science Advances(2023). DOI: 10.1126/sciadv.add

Updated on: January 23,2024

Lost metabolic fitness of CAR NK cells is key mechanism of tumor resistance, study discovers

byUniversity of Texas M. D. Anderson Cancer CenterCAR-NK cells have a distinct single-cell transcriptome and metabolic profile. Credit:Science Advances(2023). DOI: 10.1126/sciadv.add

Updated on:January 23,2024

Ryan Reynolds has urged 45-year-olds to screen for bowel cancer. But the case for screening in your 40s isn't clear cut

by Katy Bell and Paul Glasziou,The ConversationCredit: AI-generated imageLast week, actors Ryan Reynolds and Rob McElhenney released avideo of themselves getting colonoscopiesto enco

Updated on: January 03,2024

Ryan Reynolds has urged 45-year-olds to screen for bowel cancer. But the case for screening in your 40s isn't clear cut

by Katy Bell and Paul Glasziou,The ConversationCredit: AI-generated imageLast week, actors Ryan Reynolds and Rob McElhenney released avideo of themselves getting colonoscopiesto enco

Updated on:January 03,2024

Therapeutic and diagnostic functions of one antibody for pancreatic cancer

by Osaka UniversityFig.1: DKK1–CKAP4 signaling and application of the anti-CKAP4 antibody. DKK1 and CKAP4 are overexpressed in cancer cells and the PI3 kinase–AKT pathway is activated, promoting

Updated on: May 20,2024

Therapeutic and diagnostic functions of one antibody for pancreatic cancer

by Osaka UniversityFig.1: DKK1–CKAP4 signaling and application of the anti-CKAP4 antibody. DKK1 and CKAP4 are overexpressed in cancer cells and the PI3 kinase–AKT pathway is activated, promoting

Updated on:May 20,2024

Study: Antiretroviral therapy crucial in preventing non-Hodgkin lymphoma

by Michael Greenwood,Yale UniversityHIV infecting a human cell. Credit: NIHA research team led by the Yale School of Public Health has found that for people living with HIV/AIDS, both recent imm

Updated on: June 28,2024

Study: Antiretroviral therapy crucial in preventing non-Hodgkin lymphoma

by Michael Greenwood,Yale UniversityHIV infecting a human cell. Credit: NIHA research team led by the Yale School of Public Health has found that for people living with HIV/AIDS, both recent imm

Updated on:June 28,2024

miR-10b inhibition: A strategy for treating metastatic breast cancer

by Impact Journals LLCmiR-10b inhibition by MN-anti-miR10b decreases Aldefluor accumulation and impairs spheroid formation. (A) Fluorescence microscopy of representative MDA-MB-231 cells after incubat

Updated on: September 07,2024

miR-10b inhibition: A strategy for treating metastatic breast cancer

by Impact Journals LLCmiR-10b inhibition by MN-anti-miR10b decreases Aldefluor accumulation and impairs spheroid formation. (A) Fluorescence microscopy of representative MDA-MB-231 cells after incubat

Updated on:September 07,2024

Researcher explores new treatment for advanced biliary tract cancers

by Blair Willis,University of ArizonaCredit: CC0 Public DomainA new treatment that may extend survival for patients with advanced biliary tract cancers—who typically face a grim outlook with ave

Updated on: June 06,2024

Researcher explores new treatment for advanced biliary tract cancers

by Blair Willis,University of ArizonaCredit: CC0 Public DomainA new treatment that may extend survival for patients with advanced biliary tract cancers—who typically face a grim outlook with ave

Updated on:June 06,2024

Combined epigenetic and immunotherapy for blastic and classical mantle cell lymphoma

by Impact JournalsMechanisms of SCR resistance and characterization of the CD20 negative MCL cell lines 353. Credit: LeBlanc et al,Oncotarget(2022). DOI: 10.18632/oncotarget.28258A new res

Updated on: January 02,2024

Combined epigenetic and immunotherapy for blastic and classical mantle cell lymphoma

by Impact JournalsMechanisms of SCR resistance and characterization of the CD20 negative MCL cell lines 353. Credit: LeBlanc et al,Oncotarget(2022). DOI: 10.18632/oncotarget.28258A new res

Updated on:January 02,2024

Study highlights how lower-income, working cancer caregivers experience harder financial impacts

by Rachel Sauer,CU Anschutz Medical CampusCredit: Pixabay/CC0 Public DomainCancer is a disease of ripples—from symptoms that precede a diagnosis to treatment, side effects, and goals for long-te

Updated on: February 18,2024

Study highlights how lower-income, working cancer caregivers experience harder financial impacts

by Rachel Sauer,CU Anschutz Medical CampusCredit: Pixabay/CC0 Public DomainCancer is a disease of ripples—from symptoms that precede a diagnosis to treatment, side effects, and goals for long-te

Updated on:February 18,2024

Investigators reveal changes to immune status in patient tumors after radiation

by Roswell Park Comprehensive Cancer CenterCredit: Pixabay/CC0 Public DomainLittle is known about how radiation therapy to kill cancer cells affects immune cells and other components of patient tumors

Updated on: January 30,2024

Investigators reveal changes to immune status in patient tumors after radiation

by Roswell Park Comprehensive Cancer CenterCredit: Pixabay/CC0 Public DomainLittle is known about how radiation therapy to kill cancer cells affects immune cells and other components of patient tumors

Updated on:January 30,2024

Why a promising breast cancer drug doesn't work—and how to improve it

by Katherine Fenz,Rockefeller UniversityER-mediated transcriptional resistance to BD inhibition. Credit:Nature Structural & Molecular Biology(2024). DOI: 10.1038/s41594-024-01384

Updated on: September 28,2024

Why a promising breast cancer drug doesn't work—and how to improve it

by Katherine Fenz,Rockefeller UniversityER-mediated transcriptional resistance to BD inhibition. Credit:Nature Structural & Molecular Biology(2024). DOI: 10.1038/s41594-024-01384

Updated on:September 28,2024

Polyploidy study reveals why some cancers are resistant to therapeutic drugs

byOsaka UniversityOverview of the study. (A) We created unique cells with double the usual number of chromosomes to investigate the relationship between polyploidy and DNA damage. (B) After trea

Updated on: November 09,2024

Polyploidy study reveals why some cancers are resistant to therapeutic drugs

byOsaka UniversityOverview of the study. (A) We created unique cells with double the usual number of chromosomes to investigate the relationship between polyploidy and DNA damage. (B) After trea

Updated on:November 09,2024

Beating cancer-related fatigue with personalized interventions

byUniversity of TwenteFlow diagram of selection of eligible studies. Credit:European Journal of Cancer Care(2022). DOI: 10.1111/ecc.13754After diagnosis and treatment of breast cance

Updated on: January 07,2024

Beating cancer-related fatigue with personalized interventions

byUniversity of TwenteFlow diagram of selection of eligible studies. Credit:European Journal of Cancer Care(2022). DOI: 10.1111/ecc.13754After diagnosis and treatment of breast cance

Updated on:January 07,2024