Using donor CAR T cells shows promise in treating myeloma patients in phase I trial

by Bob Yirka , Medical XpressCAR T Cell Concentrations Stratified by Response. (a) CAR T cell concentrations among ALLO-715 DL3 patients that received any fludarabine/cyclophosphamide/ALLO-647 (FCA) l

Updated on: February 03,2024

Using donor CAR T cells shows promise in treating myeloma patients in phase I trial

by Bob Yirka , Medical XpressCAR T Cell Concentrations Stratified by Response. (a) CAR T cell concentrations among ALLO-715 DL3 patients that received any fludarabine/cyclophosphamide/ALLO-647 (FCA) l

Updated on:February 03,2024

Researchers develop tool that reduces errors in stem cell transplant reporting

by Children's Hospital of PhiladelphiaCredit: CC0 Public DomainResearchers at Children's Hospital of Philadelphia (CHOP) have developed a custom-built application to automate determinatio

Updated on: February 20,2024

Researchers develop tool that reduces errors in stem cell transplant reporting

by Children's Hospital of PhiladelphiaCredit: CC0 Public DomainResearchers at Children's Hospital of Philadelphia (CHOP) have developed a custom-built application to automate determinatio

Updated on:February 20,2024

Researchers discover the Achilles' heel of an aggressive brain cancer

by University of HelsinkiGlioblastoma cells (red) are known to invade the brain (blue). Figure shows patient-derived glioblastoma in murine brain treated with saline (control). Credit: Laakkonen

Updated on: June 22,2024

Researchers discover the Achilles' heel of an aggressive brain cancer

by University of HelsinkiGlioblastoma cells (red) are known to invade the brain (blue). Figure shows patient-derived glioblastoma in murine brain treated with saline (control). Credit: Laakkonen

Updated on:June 22,2024

How oncologists can ethically navigate the 'Right-To-Try' drug law

by Perelman School of Medicine at the University of PennsylvaniaCredit: CC0 Public DomainThe 2018 federal Right to Try Act allows patients with a life-threatening illness to be treated with drugs

Updated on: April 07,2024

How oncologists can ethically navigate the 'Right-To-Try' drug law

by Perelman School of Medicine at the University of PennsylvaniaCredit: CC0 Public DomainThe 2018 federal Right to Try Act allows patients with a life-threatening illness to be treated with drugs

Updated on:April 07,2024

AI tool 'DeepHRD' accelerates cancer treatment decisions

byUniversity of California - San DiegoFirst author Erik Bergstrom showcasing a biopsy analysis completed with DeepHRD, a new artificial intelligence tool that can detect clinically actionable ge

Updated on: August 28,2024

AI tool 'DeepHRD' accelerates cancer treatment decisions

byUniversity of California - San DiegoFirst author Erik Bergstrom showcasing a biopsy analysis completed with DeepHRD, a new artificial intelligence tool that can detect clinically actionable ge

Updated on:August 28,2024

Discovery could lead to new drugs to block protein that fuels bowel cancer

by Institute of Cancer ResearchUsing cryo-electron microscopy, researchers obtained a detailed map (shown in orange) of the chain-like tankyrase structure. By interpreting this map and reconstruc

Updated on: February 23,2024

Discovery could lead to new drugs to block protein that fuels bowel cancer

by Institute of Cancer ResearchUsing cryo-electron microscopy, researchers obtained a detailed map (shown in orange) of the chain-like tankyrase structure. By interpreting this map and reconstruc

Updated on:February 23,2024

Tracking the epigenetic evolution of a cancer, cell by cell

by Weill Cornell Medical CollegeDr. Dan Landau. Credit: Rene PerezA powerful new set of scientific tools developed by Weill Cornell Medicine and New York Genome Center (NYGC) researchers enables

Updated on: May 23,2024

Tracking the epigenetic evolution of a cancer, cell by cell

by Weill Cornell Medical CollegeDr. Dan Landau. Credit: Rene PerezA powerful new set of scientific tools developed by Weill Cornell Medicine and New York Genome Center (NYGC) researchers enables

Updated on:May 23,2024

Fred Hutch researchers engineer complex immunotherapy that may target relapsing leukemia

by Fred Hutchinson Cancer Research CenterDr. Marie Bleakley, a pediatric oncologist and researcher at Fred Hutch, is advancing a new approach to genetically engineer T cells. Credit: Fred HutchOc

Updated on: March 06,2024

Fred Hutch researchers engineer complex immunotherapy that may target relapsing leukemia

by Fred Hutchinson Cancer Research CenterDr. Marie Bleakley, a pediatric oncologist and researcher at Fred Hutch, is advancing a new approach to genetically engineer T cells. Credit: Fred HutchOc

Updated on:March 06,2024

Targeted therapy better for repeat kidney cancer patients than FDA-approved counterpart

by City of HopeKiller T cells surround a cancer cell. Credit: NIHKidney cancer patients who had already tried two or three different treatments had improved chances of preventing cancer progression wi

Updated on: April 14,2024

Targeted therapy better for repeat kidney cancer patients than FDA-approved counterpart

by City of HopeKiller T cells surround a cancer cell. Credit: NIHKidney cancer patients who had already tried two or three different treatments had improved chances of preventing cancer progression wi

Updated on:April 14,2024

New anti-cancer 'degrader' targets protein essential to infant leukemia

byVan Andel Research InstituteDiscovery of a first-in-class, highly potent VHL-recruiting ENL PROTAC degrader, MS41. Credit:Science Advances(2024). DOI: 10.1126/sciadv.ado1432Scienti

Updated on: September 10,2024

New anti-cancer 'degrader' targets protein essential to infant leukemia

byVan Andel Research InstituteDiscovery of a first-in-class, highly potent VHL-recruiting ENL PROTAC degrader, MS41. Credit:Science Advances(2024). DOI: 10.1126/sciadv.ado1432Scienti

Updated on:September 10,2024

Researchers use X-ray spectroscopy to explain why FLASH cancer therapy is so effective

by American Crystallographic Association (ACA)Overhead view of the XFMS experimental setup: A syringe pump pushes samples (proteins or peptides) through a capillary (blue tubing in the figure) and out

Updated on: February 18,2024

Researchers use X-ray spectroscopy to explain why FLASH cancer therapy is so effective

by American Crystallographic Association (ACA)Overhead view of the XFMS experimental setup: A syringe pump pushes samples (proteins or peptides) through a capillary (blue tubing in the figure) and out

Updated on:February 18,2024

Loss of cilia leads to melanoma

by University of ZurichPigment cells (blue/green) with cilium (light green with red base). Credit: Daniel Zingg, Netherlands Cancer InstituteMost cells in the human body have a cilium, a slender

Updated on: March 06,2024

Loss of cilia leads to melanoma

by University of ZurichPigment cells (blue/green) with cilium (light green with red base). Credit: Daniel Zingg, Netherlands Cancer InstituteMost cells in the human body have a cilium, a slender

Updated on:March 06,2024