Gene therapy advances as scientists guide jumping DNA to target faulty genes

by Matthew Campbell,University of Hawaii at ManoaIdentification of Exc+Int⁻ DNA-binding domain mutants to minimize off-target integration. Credit:Nucleic Acids Research(2025). DOI: 10.1093/nar/gkaf131

Updated on: January 01,2026

Gene therapy advances as scientists guide jumping DNA to target faulty genes

by Matthew Campbell,University of Hawaii at ManoaIdentification of Exc+Int⁻ DNA-binding domain mutants to minimize off-target integration. Credit:Nucleic Acids Research(2025). DOI: 10.1093/nar/gkaf131

Updated on:January 01,2026

RNA steps outside the cell to help guide immune responses, study suggests

byUtrecht UniversitySchematic model showing how cell-surface RNA (csRNA) is anchored to the cell membrane via heparan sulfate and RNA-binding proteins, and how it can help bring immune receptors (such

Updated on: January 13,2026

RNA steps outside the cell to help guide immune responses, study suggests

byUtrecht UniversitySchematic model showing how cell-surface RNA (csRNA) is anchored to the cell membrane via heparan sulfate and RNA-binding proteins, and how it can help bring immune receptors (such

Updated on:January 13,2026

Genetic influences on health can ripple through social groups via shared microbes

byCenter for Genomic RegulationSocially-interacting rats. Credit: Katie HollYour "roommate's" genes could be influencing the bacteria living in your gut, and vice versa, according to a s

Updated on: January 06,2026

Genetic influences on health can ripple through social groups via shared microbes

byCenter for Genomic RegulationSocially-interacting rats. Credit: Katie HollYour "roommate's" genes could be influencing the bacteria living in your gut, and vice versa, according to a s

Updated on:January 06,2026

How embryos and the uterus 'talk' during implantation

byHebrew University of Jerusalem(A) Messages released by the embryo influence how fat droplets move and function in cells lining the uterus. Courtesy: Alisa Komsky-Elbaz and Eshel Dilevsky; (B) Fat dr

Updated on: January 07,2026

How embryos and the uterus 'talk' during implantation

byHebrew University of Jerusalem(A) Messages released by the embryo influence how fat droplets move and function in cells lining the uterus. Courtesy: Alisa Komsky-Elbaz and Eshel Dilevsky; (B) Fat dr

Updated on:January 07,2026

Researchers identify 166 human pluripotent stem cell lines available for use in clinical applications

byInternational Society for Stem Cell ResearchMelissa Carpenter presents findings from the paper, Pluripotent Stem Cell Lines Available for Use in Clinical Applications: A Comprehensive Overview, at t

Updated on: January 17,2026

Researchers identify 166 human pluripotent stem cell lines available for use in clinical applications

byInternational Society for Stem Cell ResearchMelissa Carpenter presents findings from the paper, Pluripotent Stem Cell Lines Available for Use in Clinical Applications: A Comprehensive Overview, at t

Updated on:January 17,2026

Hidden 'switches' in DNA reveal new insights into Alzheimer's disease

byUniversity of New South WalesCredit: Pixabay/CC0 Public DomainA tiny percentage of our DNA—around 2%—contains 20,000-odd genes. The remaining 98%—long known as the non-coding genome, or so-called &#

Updated on: January 09,2026

Hidden 'switches' in DNA reveal new insights into Alzheimer's disease

byUniversity of New South WalesCredit: Pixabay/CC0 Public DomainA tiny percentage of our DNA—around 2%—contains 20,000-odd genes. The remaining 98%—long known as the non-coding genome, or so-called &#

Updated on:January 09,2026

Key protein ACE2 could protect against high blood pressure and diabetes

byMRC Laboratory of Medical SciencesCredit: Unsplash/CC0 Public DomainProteins circulating in the blood can reveal what's happening in the body, from how we process energy to how diseases develop.

Updated on: January 11,2026

Key protein ACE2 could protect against high blood pressure and diabetes

byMRC Laboratory of Medical SciencesCredit: Unsplash/CC0 Public DomainProteins circulating in the blood can reveal what's happening in the body, from how we process energy to how diseases develop.

Updated on:January 11,2026

Structure of dopamine-releasing neurons relates to the type of circuits they form for smell-processing, study finds

byKing's College LondonCredit: Public DomainClosely related subtypes of dopamine-releasing neurons may play entirely separate roles in processing sensory information, depending on their physical s

Updated on: January 18,2026

Structure of dopamine-releasing neurons relates to the type of circuits they form for smell-processing, study finds

byKing's College LondonCredit: Public DomainClosely related subtypes of dopamine-releasing neurons may play entirely separate roles in processing sensory information, depending on their physical s

Updated on:January 18,2026

Is aging an act of genetic sabotage? Scientists find a gene that turns off food detection after reproduction

byNagoya UniversityC. elegans roundworms engineered with fluorescent proteins to visualize neurons. Credit: Noma lab, Nagoya UniversityWhen roundworms stop reproducing, they can still move and functio

Updated on: January 28,2026

Is aging an act of genetic sabotage? Scientists find a gene that turns off food detection after reproduction

byNagoya UniversityC. elegans roundworms engineered with fluorescent proteins to visualize neurons. Credit: Noma lab, Nagoya UniversityWhen roundworms stop reproducing, they can still move and functio

Updated on:January 28,2026

Some ventilator settings can double airway stress

bySUNY Polytechnic InstituteDrs. Ahmed Abdelaal and Aarthi Sekaran recently published a paper in a special issue of MDPI'sFluids,which shows that endotracheal tube cuff design and ventilator mode

Updated on: January 17,2026

Some ventilator settings can double airway stress

bySUNY Polytechnic InstituteDrs. Ahmed Abdelaal and Aarthi Sekaran recently published a paper in a special issue of MDPI'sFluids,which shows that endotracheal tube cuff design and ventilator mode

Updated on:January 17,2026