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Hematology&Oncology
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Engineered dendritic cells boost cancer immunotherapy

Engineered dendritic cells boost cancer immunotherapy

byEcole Polytechnique Federale de LausanneEngineered dendritic cells (right) acquire tumor-derived extracellular vesicles that contain cancer antigens (left), stimulating anti-tumor immunity. Credit:

Engineered dendritic cells boost cancer immunotherapy

byEcole Polytechnique Federale de LausanneEngineered dendritic cells (right) acquire tumor-derived extracellular vesicles that contain cancer antigens (left), stimulating anti-tumor immunity. Credit:
New risk score helps predict pancreatic cancer recurrence

New risk score helps predict pancreatic cancer recurrence

byCedars-Sinai Medical CenterAxial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domainCedars-Sinai investigators, leading a multi-institutional team,

New risk score helps predict pancreatic cancer recurrence

byCedars-Sinai Medical CenterAxial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domainCedars-Sinai investigators, leading a multi-institutional team,
Link between tumor metabolism and drug efficacy in cancer cells may help advance precision chemotherapy

Link between tumor metabolism and drug efficacy in cancer cells may help advance precision chemotherapy

byStonyBrookUniversityIntracellular regulation of PRMT5 activity and development of chemical probes CBH-001 and CBH-002. Credit:Nature Communications(2025). DOI: 10.1038/s41467-025-65558-6

Link between tumor metabolism and drug efficacy in cancer cells may help advance precision chemotherapy

byStonyBrookUniversityIntracellular regulation of PRMT5 activity and development of chemical probes CBH-001 and CBH-002. Credit:Nature Communications(2025). DOI: 10.1038/s41467-025-65558-6
Nanovaccine shows great promise for treating HPV-related cancers

Nanovaccine shows great promise for treating HPV-related cancers

byUTSouthwestern Medical CenterSTING nanovaccine is designed to deliver tumor antigens (Ag) and STING agonists (diABZI, PSC7A) to the tumor and secondary lymphoid organs (SLOs) to activate antit

Nanovaccine shows great promise for treating HPV-related cancers

byUTSouthwestern Medical CenterSTING nanovaccine is designed to deliver tumor antigens (Ag) and STING agonists (diABZI, PSC7A) to the tumor and secondary lymphoid organs (SLOs) to activate antit
How scientists are hacking bacteria to treat cancer, self-destruct, then vanish without a trace

How scientists are hacking bacteria to treat cancer, self-destruct, then vanish without a trace

by Josephine Wright, Susan Woods,The ConversationCredit: CC0 Public DomainBacteria are rapidly emerging as anew classof "living medicines" used to kill cancer cells.We're still a long wa

How scientists are hacking bacteria to treat cancer, self-destruct, then vanish without a trace

by Josephine Wright, Susan Woods,The ConversationCredit: CC0 Public DomainBacteria are rapidly emerging as anew classof "living medicines" used to kill cancer cells.We're still a long wa
Combination therapy for pancreatic cancer offers new treatment approach

Combination therapy for pancreatic cancer offers new treatment approach

by Lena Bösch,University Medical Center GöttingenMini tumor models from patient-derived tissue, known as organoids, without and with therapy. Bottom: Tumors (blue) with macrophages (yellow)—immune cel

Combination therapy for pancreatic cancer offers new treatment approach

by Lena Bösch,University Medical Center GöttingenMini tumor models from patient-derived tissue, known as organoids, without and with therapy. Bottom: Tumors (blue) with macrophages (yellow)—immune cel
Cancer messenger substances disrupt muscle function and trigger muscle breakdown

Cancer messenger substances disrupt muscle function and trigger muscle breakdown

by Inka Burow,Hannover Medical SchoolDr Arnab Nayak, private lecturer, investigates the effect of pro-inflammatory messengers on muscle wasting in cancer. Credit: Tim Holler/MHHCancer patients often l

Cancer messenger substances disrupt muscle function and trigger muscle breakdown

by Inka Burow,Hannover Medical SchoolDr Arnab Nayak, private lecturer, investigates the effect of pro-inflammatory messengers on muscle wasting in cancer. Credit: Tim Holler/MHHCancer patients often l
Colorectal cancer's immune puzzle cracked: Two Treg cell types shape survival odds

Colorectal cancer's immune puzzle cracked: Two Treg cell types shape survival odds

by Ian Demsky,Memorial Sloan Kettering Cancer CenterCredit: Unsplash/CC0 Public DomainIn most solid tumors, high numbers of regulatory T (Treg) cells are associated with poorer outcomes because they d

Colorectal cancer's immune puzzle cracked: Two Treg cell types shape survival odds

by Ian Demsky,Memorial Sloan Kettering Cancer CenterCredit: Unsplash/CC0 Public DomainIn most solid tumors, high numbers of regulatory T (Treg) cells are associated with poorer outcomes because they d
Combination therapy shows potential to treat pediatric brain cancer ATRT

Combination therapy shows potential to treat pediatric brain cancer ATRT

bySt. Jude Children's Research HospitalAs published inNeuro-Oncology Pediatrics, a combination therapy may offer a new treatment strategy for atypical teratoid rhabdoid tumor (ATRT), a rare pediat

Combination therapy shows potential to treat pediatric brain cancer ATRT

bySt. Jude Children's Research HospitalAs published inNeuro-Oncology Pediatrics, a combination therapy may offer a new treatment strategy for atypical teratoid rhabdoid tumor (ATRT), a rare pediat
Blood analysis shows whether brain cancer treatment is working

Blood analysis shows whether brain cancer treatment is working

by Kate McAlpine,University of MichiganDesign and validation ofGlioExoChip using EVPs from GBM cell lines. Credit:Nature Communications(2025). DOI: 10.1038/s41467-025-65681-4The effectiveness of chemo

Blood analysis shows whether brain cancer treatment is working

by Kate McAlpine,University of MichiganDesign and validation ofGlioExoChip using EVPs from GBM cell lines. Credit:Nature Communications(2025). DOI: 10.1038/s41467-025-65681-4The effectiveness of chemo
Factoring in frailty and age could improve pancreatic cancer treatment

Factoring in frailty and age could improve pancreatic cancer treatment

bySanford-Burnham PrebysAging accelerates tumor progression in a syngeneic orthotopic PDAC mouse model. Credit:Cancer Research(2025). DOI: 10.1158/0008-5472.can-25-1904While some risk factors for canc

Factoring in frailty and age could improve pancreatic cancer treatment

bySanford-Burnham PrebysAging accelerates tumor progression in a syngeneic orthotopic PDAC mouse model. Credit:Cancer Research(2025). DOI: 10.1158/0008-5472.can-25-1904While some risk factors for canc
AI can help detect kidney cancer faster

AI can help detect kidney cancer faster

byEstonian Research CouncilVariability between individual radiologists' measurements. Credit:Communications Medicine(2025). DOI: 10.1038/s43856-025-01264-0Researchers have developed an AI-based to

AI can help detect kidney cancer faster

byEstonian Research CouncilVariability between individual radiologists' measurements. Credit:Communications Medicine(2025). DOI: 10.1038/s43856-025-01264-0Researchers have developed an AI-based to