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Hematology&Oncology
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Link between tumor metabolism and drug efficacy in cancer cells may help advance precision chemotherapy

Link between tumor metabolism and drug efficacy in cancer cells may help advance precision chemotherapy

byStonyBrookUniversityIntracellular regulation of PRMT5 activity and development of chemical probes CBH-001 and CBH-002. Credit:Nature Communications(2025). DOI: 10.1038/s41467-025-65558-6

Link between tumor metabolism and drug efficacy in cancer cells may help advance precision chemotherapy

byStonyBrookUniversityIntracellular regulation of PRMT5 activity and development of chemical probes CBH-001 and CBH-002. Credit:Nature Communications(2025). DOI: 10.1038/s41467-025-65558-6
Liquid biopsy test could lead to earlier diagnoses for numerous cancer types

Liquid biopsy test could lead to earlier diagnoses for numerous cancer types

byWileyCredit: Artem Podrez from PexelsRoutine screening is limited to only a few cancer types. New research indicates that routine liquid biopsy testing (multi-cancer early detection testing) could s

Liquid biopsy test could lead to earlier diagnoses for numerous cancer types

byWileyCredit: Artem Podrez from PexelsRoutine screening is limited to only a few cancer types. New research indicates that routine liquid biopsy testing (multi-cancer early detection testing) could s
Living longer with tailored chemotherapy—despite incurable cancer

Living longer with tailored chemotherapy—despite incurable cancer

by Anne Sliper Midling,Norwegian University of Science and TechnologyAll rapidly growing cells in the body are affected by chemotherapy. Cancer cells are targeted, but so are, for example, hair cells

Living longer with tailored chemotherapy—despite incurable cancer

by Anne Sliper Midling,Norwegian University of Science and TechnologyAll rapidly growing cells in the body are affected by chemotherapy. Cancer cells are targeted, but so are, for example, hair cells
Lung cancer's earliest stages may be driven by inflammation

Lung cancer's earliest stages may be driven by inflammation

byUniversity of Texas MD Anderson Cancer CenterSpatial transcriptomics analysis with super-pixel resolution of a human lung precursor lesion (red dash border), with colors representing different gene

Lung cancer's earliest stages may be driven by inflammation

byUniversity of Texas MD Anderson Cancer CenterSpatial transcriptomics analysis with super-pixel resolution of a human lung precursor lesion (red dash border), with colors representing different gene
Macrophage 'bodyguard' disruptors may help overcome hormone-resistant breast cancer

Macrophage 'bodyguard' disruptors may help overcome hormone-resistant breast cancer

byUniversity of Miami Leonard M. Miller School of Medicine"This triple therapy approach could be a game-changer for patients whose (breast) cancers no longer respond to standard hormone treatment

Macrophage 'bodyguard' disruptors may help overcome hormone-resistant breast cancer

byUniversity of Miami Leonard M. Miller School of Medicine"This triple therapy approach could be a game-changer for patients whose (breast) cancers no longer respond to standard hormone treatment
Medical patients face hidden time burdens: An overlooked cost of cancer care

Medical patients face hidden time burdens: An overlooked cost of cancer care

byUniversity of MinnesotaCredit: Pixabay/CC0 Public DomainTreatments for serious illnesses like cancer can be enormously time-consuming. Yet most research on cancer-related time burdens has relied on

Medical patients face hidden time burdens: An overlooked cost of cancer care

byUniversity of MinnesotaCredit: Pixabay/CC0 Public DomainTreatments for serious illnesses like cancer can be enormously time-consuming. Yet most research on cancer-related time burdens has relied on
Multiple myeloma develops differently in men and women, study reveals

Multiple myeloma develops differently in men and women, study reveals

by Candace Gwaltney,Indiana UniversitySummary of key findings. Credit:Blood Cancer Journal(2025). DOI: 10.1038/s41408-025-01362-1Researchers at the Indiana University Melvin and Bren Simon Comprehensi

Multiple myeloma develops differently in men and women, study reveals

by Candace Gwaltney,Indiana UniversitySummary of key findings. Credit:Blood Cancer Journal(2025). DOI: 10.1038/s41408-025-01362-1Researchers at the Indiana University Melvin and Bren Simon Comprehensi
Nanovaccine shows great promise for treating HPV-related cancers

Nanovaccine shows great promise for treating HPV-related cancers

byUTSouthwestern Medical CenterSTING nanovaccine is designed to deliver tumor antigens (Ag) and STING agonists (diABZI, PSC7A) to the tumor and secondary lymphoid organs (SLOs) to activate antit

Nanovaccine shows great promise for treating HPV-related cancers

byUTSouthwestern Medical CenterSTING nanovaccine is designed to deliver tumor antigens (Ag) and STING agonists (diABZI, PSC7A) to the tumor and secondary lymphoid organs (SLOs) to activate antit
New Raman imaging system detects subtle tumor signals

New Raman imaging system detects subtle tumor signals

byOpticaResearchers developed a sensitive Raman imaging system that can detect very faint signals from SERS nanoparticles that bind to tumor markers. Credit: Zhen Qiu, Michigan State UniversityResearc

New Raman imaging system detects subtle tumor signals

byOpticaResearchers developed a sensitive Raman imaging system that can detect very faint signals from SERS nanoparticles that bind to tumor markers. Credit: Zhen Qiu, Michigan State UniversityResearc
New imaging probe helps track prostate cancer and possibly treat it before resistance develops

New imaging probe helps track prostate cancer and possibly treat it before resistance develops

byWayne State UniversityUptake and distribution of fluorescent ARi-FL probes in human prostate cancer cell line. Credit:Journal of Medicinal Chemistry(2025). DOI: 10.1021/acs.jmedchem.5c00836Researche

New imaging probe helps track prostate cancer and possibly treat it before resistance develops

byWayne State UniversityUptake and distribution of fluorescent ARi-FL probes in human prostate cancer cell line. Credit:Journal of Medicinal Chemistry(2025). DOI: 10.1021/acs.jmedchem.5c00836Researche
New international study reveals major survival gaps among children with cancer

New international study reveals major survival gaps among children with cancer

byUniversity of BergenCountries with at least 25 childhood cancer cases included in the present study. Included countries are Algeria, Argentina, Bahrain, Brazil, Chile, China, Colombia, Costa Rica, E

New international study reveals major survival gaps among children with cancer

byUniversity of BergenCountries with at least 25 childhood cancer cases included in the present study. Included countries are Algeria, Argentina, Bahrain, Brazil, Chile, China, Colombia, Costa Rica, E
New risk score helps predict pancreatic cancer recurrence

New risk score helps predict pancreatic cancer recurrence

byCedars-Sinai Medical CenterAxial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domainCedars-Sinai investigators, leading a multi-institutional team,

New risk score helps predict pancreatic cancer recurrence

byCedars-Sinai Medical CenterAxial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domainCedars-Sinai investigators, leading a multi-institutional team,