99

Breakthroughs
Sub Categories on Breakthroughs
Latest Articles
Study uses metabolomics to identify novel diagnostic markers for chronic obstructive pulmonary disease

Study uses metabolomics to identify novel diagnostic markers for chronic obstructive pulmonary disease

by Cactus CommunicationsAlterations in metabolism of lipids, amino acids, glucose, nucleotides, and pulmonary and gut microbiome play a crucial role in COPD development. These metabolites have great p

Study uses metabolomics to identify novel diagnostic markers for chronic obstructive pulmonary disease

by Cactus CommunicationsAlterations in metabolism of lipids, amino acids, glucose, nucleotides, and pulmonary and gut microbiome play a crucial role in COPD development. These metabolites have great p
One in five US cancer patients join in medical research

One in five US cancer patients join in medical research

by Dennis ThompsonMore patients these days are taking part in cancer research, a new study finds.At least one in five people with cancer (22%) participate in some form of clinical research, when all t

One in five US cancer patients join in medical research

by Dennis ThompsonMore patients these days are taking part in cancer research, a new study finds.At least one in five people with cancer (22%) participate in some form of clinical research, when all t
Research provides further evidence that epigenetic changes can cause type 2 diabetes

Research provides further evidence that epigenetic changes can cause type 2 diabetes

byLund UniversityStudy design. EPIC array DNA methylation in islets of 25 T2D cases and 75 controls. RNA-seq data were available for 25 T2D cases and 72 controls. Islet DNA methylation was assoc

Research provides further evidence that epigenetic changes can cause type 2 diabetes

byLund UniversityStudy design. EPIC array DNA methylation in islets of 25 T2D cases and 75 controls. RNA-seq data were available for 25 T2D cases and 72 controls. Islet DNA methylation was assoc
Insights into epigenetics: The humanized FKBP5 mouse as a model organism

Insights into epigenetics: The humanized FKBP5 mouse as a model organism

by Anke Schlee,Max Planck SocietySummary of study design and cohorts. Credit:Molecular Psychiatry(2024). DOI: 10.1038/s41380-024-02430-xThe candidate gene FKBP5 is involved in the de

Insights into epigenetics: The humanized FKBP5 mouse as a model organism

by Anke Schlee,Max Planck SocietySummary of study design and cohorts. Credit:Molecular Psychiatry(2024). DOI: 10.1038/s41380-024-02430-xThe candidate gene FKBP5 is involved in the de
Familial Alzheimer's disease transferred via bone marrow transplant in mice

Familial Alzheimer's disease transferred via bone marrow transplant in mice

byCell PressA painting representing Alzheimer's transmissibility as reported in thisStem Cell Reportsstudy. Credit: Chaahat SinghFamilial Alzheimer's disease can be transferr

Familial Alzheimer's disease transferred via bone marrow transplant in mice

byCell PressA painting representing Alzheimer's transmissibility as reported in thisStem Cell Reportsstudy. Credit: Chaahat SinghFamilial Alzheimer's disease can be transferr
Common dry cleaning chemical linked to Parkinson's

Common dry cleaning chemical linked to Parkinson's

MARCH 14, 2023byUniversity of Rochester Medical CenterCredit: Unsplash/CC0 Public DomainA common and widely used chemical may be fueling the rise of the world's fastest growing brain conditi

Common dry cleaning chemical linked to Parkinson's

MARCH 14, 2023byUniversity of Rochester Medical CenterCredit: Unsplash/CC0 Public DomainA common and widely used chemical may be fueling the rise of the world's fastest growing brain conditi
Disruption of mitochondrial unfolded protein response yields shortening of telomeres in mouse oocytes, somatic cells

Disruption of mitochondrial unfolded protein response yields shortening of telomeres in mouse oocytes, somatic cells

FEBRUARY 21, 2024by Impact Journals LLCRepresentative confocal images of TRF1 expression and TRF/H2AX co-localization in cumulus oophorus isolated from 6-month-old wild-type and Clpp−/−mice. Cre

Disruption of mitochondrial unfolded protein response yields shortening of telomeres in mouse oocytes, somatic cells

FEBRUARY 21, 2024by Impact Journals LLCRepresentative confocal images of TRF1 expression and TRF/H2AX co-localization in cumulus oophorus isolated from 6-month-old wild-type and Clpp−/−mice. Cre
Extra fingers and hearts: Pinpointing changes to our genetic instructions that disrupt development

Extra fingers and hearts: Pinpointing changes to our genetic instructions that disrupt development

by Mario Aguilera,University of California - San DiegoChanging the instructions for development: Single-letter changes to genomes led to the formation of an extra digit (right). Credit: Fabian L

Extra fingers and hearts: Pinpointing changes to our genetic instructions that disrupt development

by Mario Aguilera,University of California - San DiegoChanging the instructions for development: Single-letter changes to genomes led to the formation of an extra digit (right). Credit: Fabian L
Enhancing hypoxia-activated prodrug anticancer therapy

Enhancing hypoxia-activated prodrug anticancer therapy

by Science China PressOn the top, (a) Chemical structure of TPZP. On the bottom, (b) Schematic diagram of combined therapy. Art by Michael Rothman. Art by Zhaohui Tang. Credit: Science China Pres

Enhancing hypoxia-activated prodrug anticancer therapy

by Science China PressOn the top, (a) Chemical structure of TPZP. On the bottom, (b) Schematic diagram of combined therapy. Art by Michael Rothman. Art by Zhaohui Tang. Credit: Science China Pres
Study with over 11,000 individuals of African descent finds genetic variants linked to glaucoma

Study with over 11,000 individuals of African descent finds genetic variants linked to glaucoma

byCell PressDiscovery of known and previously undescribed loci from the discovery mega-analysis of African ancestry individuals. Credit: Cell/Verma et al.Glaucoma is the leading cause of irrever

Study with over 11,000 individuals of African descent finds genetic variants linked to glaucoma

byCell PressDiscovery of known and previously undescribed loci from the discovery mega-analysis of African ancestry individuals. Credit: Cell/Verma et al.Glaucoma is the leading cause of irrever
Researchers create a new tool to rapidly diagnose genetic mutations

Researchers create a new tool to rapidly diagnose genetic mutations

byUniversity of CalgaryGraphical abstract. Credit:Cell Reports Methods(2024). DOI: 10.1016/j.crmeth.2024.100698Dr. Pierre Billon, Ph.D., was frustrated with the time it took to get g

Researchers create a new tool to rapidly diagnose genetic mutations

byUniversity of CalgaryGraphical abstract. Credit:Cell Reports Methods(2024). DOI: 10.1016/j.crmeth.2024.100698Dr. Pierre Billon, Ph.D., was frustrated with the time it took to get g