Team develops a single-nucleus resolution atlas of white adipose tissue in different depots

FEBRUARY 5, 2024by Higher Education PressWorkflow to perform snRNA-seq of different WAT depots. The nuclei were derived from subcutaneous (S), epididymal (E), mesenteric (M), peri-nephritic (N), and p

Updated on: March 28,2024

Team develops a single-nucleus resolution atlas of white adipose tissue in different depots

FEBRUARY 5, 2024by Higher Education PressWorkflow to perform snRNA-seq of different WAT depots. The nuclei were derived from subcutaneous (S), epididymal (E), mesenteric (M), peri-nephritic (N), and p

Updated on:March 28,2024

Glutamine metabolic switch is key to red blood cell development and disease, researchers reveal

bySt. Jude Children's Research HospitalA glutamine metabolic switch is essential for erythropoiesis. Credit:Science(2024). DOI: 10.1126/science.adh9215Blood stem cells develop th

Updated on: December 03,2024

Glutamine metabolic switch is key to red blood cell development and disease, researchers reveal

bySt. Jude Children's Research HospitalA glutamine metabolic switch is essential for erythropoiesis. Credit:Science(2024). DOI: 10.1126/science.adh9215Blood stem cells develop th

Updated on:December 03,2024

Experimental compound extends life in amyotrophic lateral sclerosis mouse model

FEBRUARY 6, 2024byUT Southwestern Medical CenterMAP4K interactome and the effect on RANGAP1 subcellular distribution.AWestern-blotting analysis of proteins after proximity labeling i

Updated on: March 25,2024

Experimental compound extends life in amyotrophic lateral sclerosis mouse model

FEBRUARY 6, 2024byUT Southwestern Medical CenterMAP4K interactome and the effect on RANGAP1 subcellular distribution.AWestern-blotting analysis of proteins after proximity labeling i

Updated on:March 25,2024

Enhancing hypoxia-activated prodrug anticancer therapy

by Science China PressOn the top, (a) Chemical structure of TPZP. On the bottom, (b) Schematic diagram of combined therapy. Art by Michael Rothman. Art by Zhaohui Tang. Credit: Science China Pres

Updated on: April 06,2024

Enhancing hypoxia-activated prodrug anticancer therapy

by Science China PressOn the top, (a) Chemical structure of TPZP. On the bottom, (b) Schematic diagram of combined therapy. Art by Michael Rothman. Art by Zhaohui Tang. Credit: Science China Pres

Updated on:April 06,2024

New recommendations make it easier for patients to give feedback on their health

FEBRUARY 29, 2024byUniversity of BirminghamCredit: CC0 Public DomainPatients providing feedback on their health during research or in clinical practice could now find it less onerous, thanks to

Updated on: March 25,2024

New recommendations make it easier for patients to give feedback on their health

FEBRUARY 29, 2024byUniversity of BirminghamCredit: CC0 Public DomainPatients providing feedback on their health during research or in clinical practice could now find it less onerous, thanks to

Updated on:March 25,2024

Study identifies epigenetic 'switches' that regulate the developmental trajectories of single cells

by Ingrid Fadelli , Medical XpressAnalysis of the developmental cell atlas. a, Workflow to obtain single-cell RNA (scRNA) expression and CUT&Tag data for three histone modifications (H3K27me3, H3K

Updated on: July 17,2024

Study identifies epigenetic 'switches' that regulate the developmental trajectories of single cells

by Ingrid Fadelli , Medical XpressAnalysis of the developmental cell atlas. a, Workflow to obtain single-cell RNA (scRNA) expression and CUT&Tag data for three histone modifications (H3K27me3, H3K

Updated on:July 17,2024

Discovery enables effective use of gene therapy for muscular dystrophies and other large-gene diseases

byUniversity of Rochester Medical CenterCredit: Pixabay/CC0 Public DomainGene therapy can effectively treat various diseases, but for some debilitating conditions like muscular dystrophies there

Updated on: November 22,2024

Discovery enables effective use of gene therapy for muscular dystrophies and other large-gene diseases

byUniversity of Rochester Medical CenterCredit: Pixabay/CC0 Public DomainGene therapy can effectively treat various diseases, but for some debilitating conditions like muscular dystrophies there

Updated on:November 22,2024

New monoclonal antibody for treating cerebral ischemia injury

FEBRUARY 27, 2024byThe University of Hong KongProfessor Ruby Hoo Lai-chong (first, right), Department of Pharmacology and Pharmacy of HKUMed, and her research team have successfully developed a

Updated on: March 30,2024

New monoclonal antibody for treating cerebral ischemia injury

FEBRUARY 27, 2024byThe University of Hong KongProfessor Ruby Hoo Lai-chong (first, right), Department of Pharmacology and Pharmacy of HKUMed, and her research team have successfully developed a

Updated on:March 30,2024

Study: PR55α-controlled PP2A inhibits p16 expression and blocks cellular senescence induction

by Impact Journals LLCPR55α level is much lower in human normal tissue specimens of older individuals compared to younger individuals and inversely correlates with p16 levels. Human normal tissue spec

Updated on: March 27,2024

Study: PR55α-controlled PP2A inhibits p16 expression and blocks cellular senescence induction

by Impact Journals LLCPR55α level is much lower in human normal tissue specimens of older individuals compared to younger individuals and inversely correlates with p16 levels. Human normal tissue spec

Updated on:March 27,2024

Case study: Drug-resistant bacteria responds to phage-antibiotic combo therapy

FEBRUARY 14, 2024 Editors' notesbyUniversity of PittsburghCredit: CC0 Public DomainIt was a last-ditch effort. For years doctors had tried to keep a patient's recurrent drug-resistant ba

Updated on: March 14,2024

Case study: Drug-resistant bacteria responds to phage-antibiotic combo therapy

FEBRUARY 14, 2024 Editors' notesbyUniversity of PittsburghCredit: CC0 Public DomainIt was a last-ditch effort. For years doctors had tried to keep a patient's recurrent drug-resistant ba

Updated on:March 14,2024

Researchers identify potential way to treat genetic epilepsy by replacing 'lost' enzyme

byThe Francis Crick InstituteCredit: Pixabay/CC0 Public DomainScientists at the Francis Crick Institute have found a new treatment target for CDKL5 deficiency disorder (CDD), one of the most com

Updated on: March 13,2024

Researchers identify potential way to treat genetic epilepsy by replacing 'lost' enzyme

byThe Francis Crick InstituteCredit: Pixabay/CC0 Public DomainScientists at the Francis Crick Institute have found a new treatment target for CDKL5 deficiency disorder (CDD), one of the most com

Updated on:March 13,2024

Long COVID may harm cognition

MARCH 3, 2024by Robin FosterIn a finding that unearths yet another way Long COVID can harm health, new research finds the condition may trigger thinking declines.Published Thursday in theNew Eng

Updated on: March 30,2024

Long COVID may harm cognition

MARCH 3, 2024by Robin FosterIn a finding that unearths yet another way Long COVID can harm health, new research finds the condition may trigger thinking declines.Published Thursday in theNew Eng

Updated on:March 30,2024