A new vision for AAV-delivered gene therapies

by Benjamin Boettner,Harvard UniversityAAVs with TLR9-inhibitory sequences incorporated into their genomes allowed significantly higher expression of a linked fluorescent reporter gene in the mo

Updated on: April 02,2024

A new vision for AAV-delivered gene therapies

by Benjamin Boettner,Harvard UniversityAAVs with TLR9-inhibitory sequences incorporated into their genomes allowed significantly higher expression of a linked fluorescent reporter gene in the mo

Updated on:April 02,2024

New compound shows early promise for treatment of Lou Gehrig's disease in preclinical models

NOVEMBER 7, 2023by Jaclyn Dunne,Medical University of South CarolinaMitochondrial membrane rearrangements are critical in recruiting p17/PERMIT-CerS1 to mitochondria. Credit:Aging Cell&nbs

Updated on: March 25,2024

New compound shows early promise for treatment of Lou Gehrig's disease in preclinical models

NOVEMBER 7, 2023by Jaclyn Dunne,Medical University of South CarolinaMitochondrial membrane rearrangements are critical in recruiting p17/PERMIT-CerS1 to mitochondria. Credit:Aging Cell&nbs

Updated on:March 25,2024

Research team investigates difference between baby formula and human milk's effect on intestinal growth

by Alexa Tomassi,Yale School of MedicineCredit: Unsplash/CC0 Public DomainAn articlepublished inGastro Hep Advancesby a team of Yale researchers and led by Lauren Smith, MD, ho

Updated on: August 08,2024

Research team investigates difference between baby formula and human milk's effect on intestinal growth

by Alexa Tomassi,Yale School of MedicineCredit: Unsplash/CC0 Public DomainAn articlepublished inGastro Hep Advancesby a team of Yale researchers and led by Lauren Smith, MD, ho

Updated on:August 08,2024

Variants in synaptic scaffolding protein PPFIA3 discovered to cause new syndromic neurodevelopmental disorder

byTexas Children's HospitalCredit: Pixabay/CC0 Public DomainAn international collaborative study has recently discovered that variants in the PPFIA3 gene cause a previously unknown syndromic

Updated on: January 09,2024

Variants in synaptic scaffolding protein PPFIA3 discovered to cause new syndromic neurodevelopmental disorder

byTexas Children's HospitalCredit: Pixabay/CC0 Public DomainAn international collaborative study has recently discovered that variants in the PPFIA3 gene cause a previously unknown syndromic

Updated on:January 09,2024

Common human gene mutations linked to a range of health conditions

byUniversity of GlasgowPCA plots of principal components calculated from Affymetrix genotype data from the 10,179 participants that had UK Biobank PC1 > 100 and PC2 > 0. (a) Participants w

Updated on: April 26,2024

Common human gene mutations linked to a range of health conditions

byUniversity of GlasgowPCA plots of principal components calculated from Affymetrix genotype data from the 10,179 participants that had UK Biobank PC1 > 100 and PC2 > 0. (a) Participants w

Updated on:April 26,2024

Scientists develop tunable organic active neural probe enabling near-sensor signal processing

byPohang University of Science and Technology(a) Structure and functional mechanism of an implantable brain signal amplification sensor created using inkjet printing technology. (b) Magnified li

Updated on: January 07,2024

Scientists develop tunable organic active neural probe enabling near-sensor signal processing

byPohang University of Science and Technology(a) Structure and functional mechanism of an implantable brain signal amplification sensor created using inkjet printing technology. (b) Magnified li

Updated on:January 07,2024

The fate of drug discovery in academia: Why is it so difficult?

FEBRUARY 5, 2024by Impact Journals LLCA typical drug discovery and development strategy. Credit:Oncotarget(2024). DOI: 10.18632/oncotarget.28552A new editorial paper titled "The fate

Updated on: March 25,2024

The fate of drug discovery in academia: Why is it so difficult?

FEBRUARY 5, 2024by Impact Journals LLCA typical drug discovery and development strategy. Credit:Oncotarget(2024). DOI: 10.18632/oncotarget.28552A new editorial paper titled "The fate

Updated on:March 25,2024

Optical biosensor rapidly detects monkeypox virus

by Susanne Clara Bard,University of California - San DiegoPrototype of PD-IRIS (a). A conical light integrating device (LID) is used to mix two wavelengths. Uniformly mixed output light at two d

Updated on: December 03,2024

Optical biosensor rapidly detects monkeypox virus

by Susanne Clara Bard,University of California - San DiegoPrototype of PD-IRIS (a). A conical light integrating device (LID) is used to mix two wavelengths. Uniformly mixed output light at two d

Updated on:December 03,2024

cGAS: Sounding the alarm on self and foreign DNA

Updated on: September 24,2024

cGAS: Sounding the alarm on self and foreign DNA

Updated on:September 24,2024

How does HIV get into the cell's center to kickstart infection?

JANUARY 24, 2024 Editors' notesbyUniversity of New South WalesIntact HIV-1 CLPs penetrate Nup98 condensates via FG-binding pocket. Credit:Nature(2024). DOI: 10.1038/s41586-023-06

Updated on: March 14,2024

How does HIV get into the cell's center to kickstart infection?

JANUARY 24, 2024 Editors' notesbyUniversity of New South WalesIntact HIV-1 CLPs penetrate Nup98 condensates via FG-binding pocket. Credit:Nature(2024). DOI: 10.1038/s41586-023-06

Updated on:March 14,2024

Nearly 40% of type 2 diabetes patients stop taking their second-line medication, finds study

byNorthwestern UniversityCredit: Unsplash/CC0 Public DomainMost patients with type 2 diabetes will end up needing to add a second-line medication after metformin—the go-to primary drug for gluco

Updated on: January 26,2024

Nearly 40% of type 2 diabetes patients stop taking their second-line medication, finds study

byNorthwestern UniversityCredit: Unsplash/CC0 Public DomainMost patients with type 2 diabetes will end up needing to add a second-line medication after metformin—the go-to primary drug for gluco

Updated on:January 26,2024

Positive parenting strategies can reduce child maltreatment

byUniversity of QueenslandOrganization engagement by local government area. Credit:Child Maltreatment(2024). DOI: 10.1177/10775595241259994University of Queensland research shows chi

Updated on: August 08,2024

Positive parenting strategies can reduce child maltreatment

byUniversity of QueenslandOrganization engagement by local government area. Credit:Child Maltreatment(2024). DOI: 10.1177/10775595241259994University of Queensland research shows chi

Updated on:August 08,2024