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Study confirms how RNA chemical modifications benefit HIV-1

Study confirms how RNA chemical modifications benefit HIV-1

by Emily Caldwell,The Ohio State UniversityHIV-1 Virus. Credit: J Roberto Trujillo/WikipediaA chemical modification in the HIV-1 RNA genome whose function has been a matter of scientific debate

Study confirms how RNA chemical modifications benefit HIV-1

by Emily Caldwell,The Ohio State UniversityHIV-1 Virus. Credit: J Roberto Trujillo/WikipediaA chemical modification in the HIV-1 RNA genome whose function has been a matter of scientific debate
New tool to analyze blood platelets holds major medical potential

New tool to analyze blood platelets holds major medical potential

by Carol Clark,Emory UniversityCredit: Pixabay/CC0 Public DomainA novel technique to test platelet function within a person's blood sample is faster, easier and more precise than methods cur

New tool to analyze blood platelets holds major medical potential

by Carol Clark,Emory UniversityCredit: Pixabay/CC0 Public DomainA novel technique to test platelet function within a person's blood sample is faster, easier and more precise than methods cur
Study identifies factors associated with long-term use of FDA-approved anti-obesity medications

Study identifies factors associated with long-term use of FDA-approved anti-obesity medications

byCleveland ClinicPercentage of patients who were persistent with antiobesity medication (AOM) at early stage, medium term, and long term, by AOM agent. [Color figure can be viewed atwiley

Study identifies factors associated with long-term use of FDA-approved anti-obesity medications

byCleveland ClinicPercentage of patients who were persistent with antiobesity medication (AOM) at early stage, medium term, and long term, by AOM agent. [Color figure can be viewed atwiley
Transdifferentiation with RNA sequencing aids diagnosis of genetic disorders

Transdifferentiation with RNA sequencing aids diagnosis of genetic disorders

by Molly Chiu,Baylor College of MedicineCredit: Unsplash/CC0 Public DomainResearchers at Baylor College of Medicine have tested the feasibility of using human cell transdifferentiation with RNA

Transdifferentiation with RNA sequencing aids diagnosis of genetic disorders

by Molly Chiu,Baylor College of MedicineCredit: Unsplash/CC0 Public DomainResearchers at Baylor College of Medicine have tested the feasibility of using human cell transdifferentiation with RNA
Drug shows promise for slowing progression of rare, painful genetic disease

Drug shows promise for slowing progression of rare, painful genetic disease

by National Institutes of HealthCredit: CC0 Public DomainA drug used to treat certain bone diseases shows promise for slowing the progression of a rare, painful genetic condition that causes exce

Drug shows promise for slowing progression of rare, painful genetic disease

by National Institutes of HealthCredit: CC0 Public DomainA drug used to treat certain bone diseases shows promise for slowing the progression of a rare, painful genetic condition that causes exce
Five-day antibiotic course noninferior for pediatric febrile UTI

Five-day antibiotic course noninferior for pediatric febrile UTI

by Elana GotkineFor young children with febrile urinary tract infection (fUTI), a five-day amoxicillin-clavulanate course is noninferior to a 10-day course for recurrence of UTI within 30 days after c

Five-day antibiotic course noninferior for pediatric febrile UTI

by Elana GotkineFor young children with febrile urinary tract infection (fUTI), a five-day amoxicillin-clavulanate course is noninferior to a 10-day course for recurrence of UTI within 30 days after c
Many antibiotic courses for common infections not in line with guidelines

Many antibiotic courses for common infections not in line with guidelines

by British Medical JournalCredit: CC0 Public DomainMany antibiotic courses prescribed for common infections treated in English primary care (general practices and community services) exceed the r

Many antibiotic courses for common infections not in line with guidelines

by British Medical JournalCredit: CC0 Public DomainMany antibiotic courses prescribed for common infections treated in English primary care (general practices and community services) exceed the r
The double-edge sword of CRISPR application for in vivo studies

The double-edge sword of CRISPR application for in vivo studies

by Impact Journals LLCWorkflow illustration. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.28459A new editorial paper titled "The double-edge sword of CRISPR application for in vi

The double-edge sword of CRISPR application for in vivo studies

by Impact Journals LLCWorkflow illustration. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.28459A new editorial paper titled "The double-edge sword of CRISPR application for in vi
Researchers develop framework to identify molecules responsible for chemotherapy resistance

Researchers develop framework to identify molecules responsible for chemotherapy resistance

JANUARY 18, 2024byKarolinska InstitutetCredit:iScience(2024). https://www.cell.com/iscience/fulltext/S2589-0042(24)00128-7Researchers at Karolinska Institutet and SciLifeLab demonstr

Researchers develop framework to identify molecules responsible for chemotherapy resistance

JANUARY 18, 2024byKarolinska InstitutetCredit:iScience(2024). https://www.cell.com/iscience/fulltext/S2589-0042(24)00128-7Researchers at Karolinska Institutet and SciLifeLab demonstr
Tackling antibiotic resistance when treating pneumonia

Tackling antibiotic resistance when treating pneumonia

JANUARY 18, 2024byUniversity of LiverpoolSchematic summary of the molecular mechanisms in Pseudomonas aeruginosa associated with the observed phenotypic changes in the rabbit model. OprD-associa

Tackling antibiotic resistance when treating pneumonia

JANUARY 18, 2024byUniversity of LiverpoolSchematic summary of the molecular mechanisms in Pseudomonas aeruginosa associated with the observed phenotypic changes in the rabbit model. OprD-associa
Study finds Paxlovid treatment does not reduce risk of long COVID

Study finds Paxlovid treatment does not reduce risk of long COVID

byUniversity of California, San FranciscoIn all models, treatment with oral nirmatrelvir was not associated with lower odds of patient reported Long COVID symptoms with confidence intervals that

Study finds Paxlovid treatment does not reduce risk of long COVID

byUniversity of California, San FranciscoIn all models, treatment with oral nirmatrelvir was not associated with lower odds of patient reported Long COVID symptoms with confidence intervals that
Drug development advances in beneficial loss-of-function mutation targets validated by human genetics

Drug development advances in beneficial loss-of-function mutation targets validated by human genetics

by Sichuan International Medical Exchange and Promotion AssociationTargets primarily include PCSK9, ANGPTL3, HSD17B13, KHK, ASGR1, GPR75, CIDEB, and INHBE. Drug types primarily include small molecules

Drug development advances in beneficial loss-of-function mutation targets validated by human genetics

by Sichuan International Medical Exchange and Promotion AssociationTargets primarily include PCSK9, ANGPTL3, HSD17B13, KHK, ASGR1, GPR75, CIDEB, and INHBE. Drug types primarily include small molecules