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Breakthroughs
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Scientists improve the equation in FDA guidance predicting drug interactions

Scientists improve the equation in FDA guidance predicting drug interactions

by Institute for Basic ScienceThe new equation provides more accurate predictions than the conventional FDA equation. The FDA equation with Fg estimated assuming Fa = 1 underpredicts the area und

Scientists improve the equation in FDA guidance predicting drug interactions

by Institute for Basic ScienceThe new equation provides more accurate predictions than the conventional FDA equation. The FDA equation with Fg estimated assuming Fa = 1 underpredicts the area und
Biological mechanism discovered that could lead to new treatments for neurological disorders and cancers

Biological mechanism discovered that could lead to new treatments for neurological disorders and cancers

by Ann & Robert H. Lurie Children's Hospital of ChicagoCredit: Pixabay/CC0 Public DomainThe lab of Yongchao C. Ma, Ph.D., at Stanley Manne Children's Research Institute at Ann & R

Biological mechanism discovered that could lead to new treatments for neurological disorders and cancers

by Ann & Robert H. Lurie Children's Hospital of ChicagoCredit: Pixabay/CC0 Public DomainThe lab of Yongchao C. Ma, Ph.D., at Stanley Manne Children's Research Institute at Ann & R
Patients regain much weight after stopping new obesity drug: Study

Patients regain much weight after stopping new obesity drug: Study

This is an image of a weight scale. Credit: CDC/Debora CartagenaA new generation of obesity drugs often delivers dramatic weight loss, but many patients wonder what happens when they stop treatment.On

Patients regain much weight after stopping new obesity drug: Study

This is an image of a weight scale. Credit: CDC/Debora CartagenaA new generation of obesity drugs often delivers dramatic weight loss, but many patients wonder what happens when they stop treatment.On
Super permeable wearable electronics developed for stable, long-term biosignal monitoring

Super permeable wearable electronics developed for stable, long-term biosignal monitoring

by Michael Gibb,City University of Hong KongThe permeable wearable electronics developed by the team for long-term biosignal monitoring. Credit: City University of Hong KongSuper wearable electr

Super permeable wearable electronics developed for stable, long-term biosignal monitoring

by Michael Gibb,City University of Hong KongThe permeable wearable electronics developed by the team for long-term biosignal monitoring. Credit: City University of Hong KongSuper wearable electr
Study identifies factors that affect antibiotic prescribing for acne

Study identifies factors that affect antibiotic prescribing for acne

by Elana GotkineMultiple salient factors affect long-term antibiotic prescribing practices for acne, according to a studypublishedinJAMA Dermatology.Ronnie A. Festok, from the Emory

Study identifies factors that affect antibiotic prescribing for acne

by Elana GotkineMultiple salient factors affect long-term antibiotic prescribing practices for acne, according to a studypublishedinJAMA Dermatology.Ronnie A. Festok, from the Emory
Study looks at ways to predict when a migraine attack will occur

Study looks at ways to predict when a migraine attack will occur

JANUARY 24, 2024byAmerican Academy of NeurologyCredit: Sasha Wolff/WikipediaMigraine is often under-diagnosed and untreated, and even when it is treated, it can be difficult to treat early enoug

Study looks at ways to predict when a migraine attack will occur

JANUARY 24, 2024byAmerican Academy of NeurologyCredit: Sasha Wolff/WikipediaMigraine is often under-diagnosed and untreated, and even when it is treated, it can be difficult to treat early enoug
Scientists develop an agent capable of selectively inhibiting the body's stress response

Scientists develop an agent capable of selectively inhibiting the body's stress response

JANUARY 22, 2024by Daniel Meierhans,ETH ZurichThe DEGs we identified upon 2 h, and 18 h of DEX treatments in A549 cells align with the other existing RNAseq and ChIP-seq datasets. Credit:N

Scientists develop an agent capable of selectively inhibiting the body's stress response

JANUARY 22, 2024by Daniel Meierhans,ETH ZurichThe DEGs we identified upon 2 h, and 18 h of DEX treatments in A549 cells align with the other existing RNAseq and ChIP-seq datasets. Credit:N
New 'dictionary' of immune responses reveals far more complexity in the immune system than previously thought

New 'dictionary' of immune responses reveals far more complexity in the immune system than previously thought

by Allessandra DiCorato,Broad Institute of MIT and HarvardCytokine production map by cell type. Credit:Nature(2023). DOI: 10.1038/s41586-023-06816-9The immune system can carry out ma

New 'dictionary' of immune responses reveals far more complexity in the immune system than previously thought

by Allessandra DiCorato,Broad Institute of MIT and HarvardCytokine production map by cell type. Credit:Nature(2023). DOI: 10.1038/s41586-023-06816-9The immune system can carry out ma
Experts release the latest guide for systematic reviews of preclinical research

Experts release the latest guide for systematic reviews of preclinical research

byRadboud UniversityCredit: Unsplash/CC0 Public DomainA new publication inNature Reviews Methods Primersprovides essential guidance for conducting rigorous systematic reviews on stud

Experts release the latest guide for systematic reviews of preclinical research

byRadboud UniversityCredit: Unsplash/CC0 Public DomainA new publication inNature Reviews Methods Primersprovides essential guidance for conducting rigorous systematic reviews on stud
Study finds cilostazol is well tolerated but doesn't prevent cognitive decline

Study finds cilostazol is well tolerated but doesn't prevent cognitive decline

DECEMBER 6, 2023by National Cerebral and Cardiovascular CenterCredit: JAMA Network Open/ National Cerebral and Cardiovascular CenterA recent study demonstrated the safety of cilostazol in patients wit

Study finds cilostazol is well tolerated but doesn't prevent cognitive decline

DECEMBER 6, 2023by National Cerebral and Cardiovascular CenterCredit: JAMA Network Open/ National Cerebral and Cardiovascular CenterA recent study demonstrated the safety of cilostazol in patients wit
Tucatinib plus trastuzumab emtansine may benefit patients with advanced or metastatic HER2-positive breast cancer

Tucatinib plus trastuzumab emtansine may benefit patients with advanced or metastatic HER2-positive breast cancer

byAmerican Association for Cancer ResearchCredit: Unsplash/CC0 Public DomainA combination of two HER2-targeted drugs, tucatinib (Tukysa) and trastuzumab emtansine (Kadcyla, T-DM1), extended prog

Tucatinib plus trastuzumab emtansine may benefit patients with advanced or metastatic HER2-positive breast cancer

byAmerican Association for Cancer ResearchCredit: Unsplash/CC0 Public DomainA combination of two HER2-targeted drugs, tucatinib (Tukysa) and trastuzumab emtansine (Kadcyla, T-DM1), extended prog