Liver fibrosis 'off switch' discovered in mice

by University of California - San DiegoCredit: CC0 Public DomainChronic alcohol abuse and hepatitis can injure the liver, often leading to a buildup of collagen and scar tissue. Understanding thi

Updated on: March 25,2024

Liver fibrosis 'off switch' discovered in mice

by University of California - San DiegoCredit: CC0 Public DomainChronic alcohol abuse and hepatitis can injure the liver, often leading to a buildup of collagen and scar tissue. Understanding thi

Updated on:March 25,2024

Raspberry Pi-based system accurate for detecting facial palsy

DECEMBER 31, 2023by Elana GotkineA Raspberry Pi device with a digital camera and a deep learning algorithm can detect facial palsy (FP) with high accuracy, according to a study recently published in&n

Updated on: March 15,2024

Raspberry Pi-based system accurate for detecting facial palsy

DECEMBER 31, 2023by Elana GotkineA Raspberry Pi device with a digital camera and a deep learning algorithm can detect facial palsy (FP) with high accuracy, according to a study recently published in&n

Updated on:March 15,2024

Study finds embryos in hungry mouse moms postpone development

byThe Company of BiologistsA mouse embryo (blastocyst) that has paused its development due to nutrient depletion. Credit: Jiajia YeIt's challenging to sustain a pregnancy when food is short,

Updated on: April 28,2024

Study finds embryos in hungry mouse moms postpone development

byThe Company of BiologistsA mouse embryo (blastocyst) that has paused its development due to nutrient depletion. Credit: Jiajia YeIt's challenging to sustain a pregnancy when food is short,

Updated on:April 28,2024

Variants in synaptic scaffolding protein PPFIA3 discovered to cause new syndromic neurodevelopmental disorder

byTexas Children's HospitalCredit: Pixabay/CC0 Public DomainAn international collaborative study has recently discovered that variants in the PPFIA3 gene cause a previously unknown syndromic

Updated on: January 09,2024

Variants in synaptic scaffolding protein PPFIA3 discovered to cause new syndromic neurodevelopmental disorder

byTexas Children's HospitalCredit: Pixabay/CC0 Public DomainAn international collaborative study has recently discovered that variants in the PPFIA3 gene cause a previously unknown syndromic

Updated on:January 09,2024

Scientists improve the equation in FDA guidance predicting drug interactions

by Institute for Basic ScienceThe new equation provides more accurate predictions than the conventional FDA equation. The FDA equation with Fg estimated assuming Fa = 1 underpredicts the area und

Updated on: February 05,2024

Scientists improve the equation in FDA guidance predicting drug interactions

by Institute for Basic ScienceThe new equation provides more accurate predictions than the conventional FDA equation. The FDA equation with Fg estimated assuming Fa = 1 underpredicts the area und

Updated on:February 05,2024

Evaluating selpercatinib for the treatment of non-small cell lung cancer

by D'Or Institute for Research and EducationCredit: Unsplash/CC0 Public DomainA phase III LIBRETTO-431 multicenter study has evaluated the efficacy and safety of selpercatinib compared to control

Updated on: January 26,2024

Evaluating selpercatinib for the treatment of non-small cell lung cancer

by D'Or Institute for Research and EducationCredit: Unsplash/CC0 Public DomainA phase III LIBRETTO-431 multicenter study has evaluated the efficacy and safety of selpercatinib compared to control

Updated on:January 26,2024

Biological mechanism discovered that could lead to new treatments for neurological disorders and cancers

by Ann & Robert H. Lurie Children's Hospital of ChicagoCredit: Pixabay/CC0 Public DomainThe lab of Yongchao C. Ma, Ph.D., at Stanley Manne Children's Research Institute at Ann & R

Updated on: April 06,2024

Biological mechanism discovered that could lead to new treatments for neurological disorders and cancers

by Ann & Robert H. Lurie Children's Hospital of ChicagoCredit: Pixabay/CC0 Public DomainThe lab of Yongchao C. Ma, Ph.D., at Stanley Manne Children's Research Institute at Ann & R

Updated on:April 06,2024

New 'dictionary' of immune responses reveals far more complexity in the immune system than previously thought

by Allessandra DiCorato,Broad Institute of MIT and HarvardCytokine production map by cell type. Credit:Nature(2023). DOI: 10.1038/s41586-023-06816-9The immune system can carry out ma

Updated on: January 26,2024

New 'dictionary' of immune responses reveals far more complexity in the immune system than previously thought

by Allessandra DiCorato,Broad Institute of MIT and HarvardCytokine production map by cell type. Credit:Nature(2023). DOI: 10.1038/s41586-023-06816-9The immune system can carry out ma

Updated on:January 26,2024

Understaffed nursing homes more likely to overuse antipsychotics as 'chemical restraints,' study finds

byNew York UniversityCredit: Pixabay/CC0 Public DomainNursing homes in disadvantaged communities are more likely to overmedicate residents with antipsychotics, especially homes that are understa

Updated on: April 28,2024

Understaffed nursing homes more likely to overuse antipsychotics as 'chemical restraints,' study finds

byNew York UniversityCredit: Pixabay/CC0 Public DomainNursing homes in disadvantaged communities are more likely to overmedicate residents with antipsychotics, especially homes that are understa

Updated on:April 28,2024

Innovative double-layer polysaccharide hydrogel shows promise for intestine-targeted oral delivery of probiotics

by Engineering(a) Design rationale of the DPH; (b) mechanism of intestine-targeted delivery. Credit: Wen-Can Huang et al.A research team led by Changhu Xue and Xiangzhao Mao from the Ocean University

Updated on: January 06,2024

Innovative double-layer polysaccharide hydrogel shows promise for intestine-targeted oral delivery of probiotics

by Engineering(a) Design rationale of the DPH; (b) mechanism of intestine-targeted delivery. Credit: Wen-Can Huang et al.A research team led by Changhu Xue and Xiangzhao Mao from the Ocean University

Updated on:January 06,2024

cGAS: Sounding the alarm on self and foreign DNA

Updated on: September 24,2024

cGAS: Sounding the alarm on self and foreign DNA

Updated on:September 24,2024

Circuit-specific gene therapy brings new hope for treatment of Parkinson's disease

byChinese Academy of SciencesRetrograde AAV selectively targets D1-MSNs and rescues parkinsonian symptoms with chemogenetic modulation. Credit: SIATResearchers from the Shenzhen Institute of Adv

Updated on: March 14,2024

Circuit-specific gene therapy brings new hope for treatment of Parkinson's disease

byChinese Academy of SciencesRetrograde AAV selectively targets D1-MSNs and rescues parkinsonian symptoms with chemogenetic modulation. Credit: SIATResearchers from the Shenzhen Institute of Adv

Updated on:March 14,2024