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Breakthroughs
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Medicinal herb found to inhibit acetylation of eNOS in vascular dysfunction

Medicinal herb found to inhibit acetylation of eNOS in vascular dysfunction

by Impact Journals LLCAGE enhances endothelial relaxation in aorta rings. (A) Representative traces under specified conditions. (B) Percentage of relaxation proportional to Ach concentration. (C) Maxi

Medicinal herb found to inhibit acetylation of eNOS in vascular dysfunction

by Impact Journals LLCAGE enhances endothelial relaxation in aorta rings. (A) Representative traces under specified conditions. (B) Percentage of relaxation proportional to Ach concentration. (C) Maxi
Pharmacologic restraint used in 3 percent of pediatric mental health admissions

Pharmacologic restraint used in 3 percent of pediatric mental health admissions

by Elana GotkineThe use of pharmacologic restraints occurs in 3 percent of hospitalizations for children admitted with a primary mental health diagnosis, according to a study published online Dec. 11

Pharmacologic restraint used in 3 percent of pediatric mental health admissions

by Elana GotkineThe use of pharmacologic restraints occurs in 3 percent of hospitalizations for children admitted with a primary mental health diagnosis, according to a study published online Dec. 11
Circuit-specific gene therapy brings new hope for treatment of Parkinson's disease

Circuit-specific gene therapy brings new hope for treatment of Parkinson's disease

byChinese Academy of SciencesRetrograde AAV selectively targets D1-MSNs and rescues parkinsonian symptoms with chemogenetic modulation. Credit: SIATResearchers from the Shenzhen Institute of Adv

Circuit-specific gene therapy brings new hope for treatment of Parkinson's disease

byChinese Academy of SciencesRetrograde AAV selectively targets D1-MSNs and rescues parkinsonian symptoms with chemogenetic modulation. Credit: SIATResearchers from the Shenzhen Institute of Adv
Oleic acid: A potential therapy for people with a rare genetic condition

Oleic acid: A potential therapy for people with a rare genetic condition

byUniversity of California, Los AngelesCredit: Pixabay/CC0 Public DomainA mutation in a protein regulating natural killer (NK) cells' function is at the root of immune deficiency in some peo

Oleic acid: A potential therapy for people with a rare genetic condition

byUniversity of California, Los AngelesCredit: Pixabay/CC0 Public DomainA mutation in a protein regulating natural killer (NK) cells' function is at the root of immune deficiency in some peo
Research team discovers potential Alzheimer's drug

Research team discovers potential Alzheimer's drug

FEBRUARY 6, 2024by University of Arkansas for Medical SciencesMolecular docking predicts a CLEAR DNA-binding region in ApoE4. a The DNA-binding region of ApoE4, as defined by molecular modeling. b The

Research team discovers potential Alzheimer's drug

FEBRUARY 6, 2024by University of Arkansas for Medical SciencesMolecular docking predicts a CLEAR DNA-binding region in ApoE4. a The DNA-binding region of ApoE4, as defined by molecular modeling. b The
Researchers identify new biomarker in quality of blood donations

Researchers identify new biomarker in quality of blood donations

by Kelsea Pieters,CU Anschutz Medical CampusCredit: CC0 Public DomainA collaborative cohort of researchers, led by University of Colorado Anschutz Medical Campus professor Angelo D'Alessandr

Researchers identify new biomarker in quality of blood donations

by Kelsea Pieters,CU Anschutz Medical CampusCredit: CC0 Public DomainA collaborative cohort of researchers, led by University of Colorado Anschutz Medical Campus professor Angelo D'Alessandr
Longitudinal characterization of behavioral, morphological and transcriptomic changes in a tauopathy mouse model

Longitudinal characterization of behavioral, morphological and transcriptomic changes in a tauopathy mouse model

by Impact Journals LLCGene expression profiling revealed various patterns of changes in PFC and hippocampus of P301S mice at different ages. Credit:Aging(2023). DOI: 10.18632/aging.205057A

Longitudinal characterization of behavioral, morphological and transcriptomic changes in a tauopathy mouse model

by Impact Journals LLCGene expression profiling revealed various patterns of changes in PFC and hippocampus of P301S mice at different ages. Credit:Aging(2023). DOI: 10.18632/aging.205057A
Researchers pinpoint issue that could be hampering common chemotherapy drug

Researchers pinpoint issue that could be hampering common chemotherapy drug

by Anika Hazra,University of TorontoGenome-wide CRISPR–Cas9 screens reveal modulators of gemcitabine sensitivity. Credit:Nature Cancer(2024). DOI: 10.1038/s43018-024-00742-zResearche

Researchers pinpoint issue that could be hampering common chemotherapy drug

by Anika Hazra,University of TorontoGenome-wide CRISPR–Cas9 screens reveal modulators of gemcitabine sensitivity. Credit:Nature Cancer(2024). DOI: 10.1038/s43018-024-00742-zResearche
Understaffed nursing homes more likely to overuse antipsychotics as 'chemical restraints,' study finds

Understaffed nursing homes more likely to overuse antipsychotics as 'chemical restraints,' study finds

byNew York UniversityCredit: Pixabay/CC0 Public DomainNursing homes in disadvantaged communities are more likely to overmedicate residents with antipsychotics, especially homes that are understa

Understaffed nursing homes more likely to overuse antipsychotics as 'chemical restraints,' study finds

byNew York UniversityCredit: Pixabay/CC0 Public DomainNursing homes in disadvantaged communities are more likely to overmedicate residents with antipsychotics, especially homes that are understa
Study identifies factors that affect antibiotic prescribing for acne

Study identifies factors that affect antibiotic prescribing for acne

by Elana GotkineMultiple salient factors affect long-term antibiotic prescribing practices for acne, according to a studypublishedinJAMA Dermatology.Ronnie A. Festok, from the Emory

Study identifies factors that affect antibiotic prescribing for acne

by Elana GotkineMultiple salient factors affect long-term antibiotic prescribing practices for acne, according to a studypublishedinJAMA Dermatology.Ronnie A. Festok, from the Emory
How the body switches out of 'fight' mode: Study shows hormones reprogram metabolism of immune cells

How the body switches out of 'fight' mode: Study shows hormones reprogram metabolism of immune cells

byCharité - Universitätsmedizin BerlinA macrophage activated by an inflammatory stimulus after being treated with cortisone. Cortisone affects not only the genes in the nucleus (blue), but also

How the body switches out of 'fight' mode: Study shows hormones reprogram metabolism of immune cells

byCharité - Universitätsmedizin BerlinA macrophage activated by an inflammatory stimulus after being treated with cortisone. Cortisone affects not only the genes in the nucleus (blue), but also