New method eradicates deadly brain tumors by 'starving' them of energy source

byTel Aviv UniversityDr. Lior Mayo and students. Credit: Tel Aviv UniversityA groundbreaking study at Tel Aviv University effectively eradicated glioblastoma, a highly lethal type of brain cance

Updated on: January 13,2024

New method eradicates deadly brain tumors by 'starving' them of energy source

byTel Aviv UniversityDr. Lior Mayo and students. Credit: Tel Aviv UniversityA groundbreaking study at Tel Aviv University effectively eradicated glioblastoma, a highly lethal type of brain cance

Updated on:January 13,2024

Mapping lactylome in hepatocellular carcinoma reveals new mechanisms of metabolic adaptation

by Liu Jia,Chinese Academy of SciencesCredit: Pixabay/CC0 Public DomainLactate, a major product of glycolysis in mammals, is significantly increased in pathological states such as tumors, sepsis

Updated on: February 20,2024

Mapping lactylome in hepatocellular carcinoma reveals new mechanisms of metabolic adaptation

by Liu Jia,Chinese Academy of SciencesCredit: Pixabay/CC0 Public DomainLactate, a major product of glycolysis in mammals, is significantly increased in pathological states such as tumors, sepsis

Updated on:February 20,2024

Review covers progress in immunotherapy for esophageal cancer

by Cactus CommunicationsMultiple ongoing clinical trials are being conducted to test the potential of ICIs as an adjuvant therapy for resectable esophageal cancer. The results of these trials could ce

Updated on: January 22,2024

Review covers progress in immunotherapy for esophageal cancer

by Cactus CommunicationsMultiple ongoing clinical trials are being conducted to test the potential of ICIs as an adjuvant therapy for resectable esophageal cancer. The results of these trials could ce

Updated on:January 22,2024

Researchers uncover new targets for breast cancers resistant to standard therapies

by Leslie Cantu,Medical University of South CarolinaSOC therapy commonly induces DNA damage, BRCAness and toxic PARP1 trapping, leading to transcriptional blockage and growth inhibition in ER+ b

Updated on: June 22,2024

Researchers uncover new targets for breast cancers resistant to standard therapies

by Leslie Cantu,Medical University of South CarolinaSOC therapy commonly induces DNA damage, BRCAness and toxic PARP1 trapping, leading to transcriptional blockage and growth inhibition in ER+ b

Updated on:June 22,2024

Peripheral surrogates of tumor burden to guide therapeutic strategies for HPV-associated malignancies

by Impact Journals LLCTumor intrinsic and extrinsic factors in the periphery that can serve as proxies of tumor burden. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.28487A new review

Updated on: January 22,2024

Peripheral surrogates of tumor burden to guide therapeutic strategies for HPV-associated malignancies

by Impact Journals LLCTumor intrinsic and extrinsic factors in the periphery that can serve as proxies of tumor burden. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.28487A new review

Updated on:January 22,2024

Researchers identify mechanism of resistance to BRAF inhibitors in melanoma

by H. Lee Moffitt Cancer Center & Research InstituteMelanoma in skin biopsy with H&E stain—this case may represent superficial spreading melanoma. Credit: Wikipedia/CC BY-SA 3.0Melanoma i

Updated on: June 08,2024

Researchers identify mechanism of resistance to BRAF inhibitors in melanoma

by H. Lee Moffitt Cancer Center & Research InstituteMelanoma in skin biopsy with H&E stain—this case may represent superficial spreading melanoma. Credit: Wikipedia/CC BY-SA 3.0Melanoma i

Updated on:June 08,2024

Study reveals factors that influence participation in bowel cancer screening

by Isabelle Dubach,University of New South WalesCredit: Unsplash/CC0 Public DomainA new, Australian-first study by Cancer Council NSW has shed light on the factors that influence whether or not

Updated on: July 02,2024

Study reveals factors that influence participation in bowel cancer screening

by Isabelle Dubach,University of New South WalesCredit: Unsplash/CC0 Public DomainA new, Australian-first study by Cancer Council NSW has shed light on the factors that influence whether or not

Updated on:July 02,2024

Race/ethnicity, socioeconomics, age contribute to disparities in cancer death

by Elana GotkineFactors contributing to disparities in cancer death include race/ethnicity, socioeconomic status, geographic location, and age, according to a study published online Nov. 14 inCA

Updated on: April 07,2024

Race/ethnicity, socioeconomics, age contribute to disparities in cancer death

by Elana GotkineFactors contributing to disparities in cancer death include race/ethnicity, socioeconomic status, geographic location, and age, according to a study published online Nov. 14 inCA

Updated on:April 07,2024

Novel allogeneic CAR T cell therapy shows promising results in patients with metastatic clear cell renal cell carcinoma

byUniversity of Texas M. D. Anderson Cancer CenterCredit: Pixabay/CC0 Public DomainThe CD70-targeting allogeneic chimeric antigen receptor (CAR) T cell therapy, ALLO-316, demonstrated encouragin

Updated on: January 15,2024

Novel allogeneic CAR T cell therapy shows promising results in patients with metastatic clear cell renal cell carcinoma

byUniversity of Texas M. D. Anderson Cancer CenterCredit: Pixabay/CC0 Public DomainThe CD70-targeting allogeneic chimeric antigen receptor (CAR) T cell therapy, ALLO-316, demonstrated encouragin

Updated on:January 15,2024

Two for the price of one: Mechanistic insights lead to drug repositioning

by University of TsukubaMolecular mechanism at a glance. SFN binds with SKP1 to sequester it in cytoplasm,resulting in the obstruction of SCFFBW7 598 complex formation. Oncoproteins including cyc

Updated on: May 23,2024

Two for the price of one: Mechanistic insights lead to drug repositioning

by University of TsukubaMolecular mechanism at a glance. SFN binds with SKP1 to sequester it in cytoplasm,resulting in the obstruction of SCFFBW7 598 complex formation. Oncoproteins including cyc

Updated on:May 23,2024

Study uncovers how B cells react to skin cancer

by King's College LondonSpatial transcriptomic coupled with high throughput intratumoral antibody repertoire analyses suggest an active but aberrant B cell response.aRepresentativ

Updated on: February 23,2024

Study uncovers how B cells react to skin cancer

by King's College LondonSpatial transcriptomic coupled with high throughput intratumoral antibody repertoire analyses suggest an active but aberrant B cell response.aRepresentativ

Updated on:February 23,2024

Previously unidentified proteins suggest new way to diagnose ovarian cancer

by Nagoya UniversityExtracellular vesicles (EVs) are vesicles with lipid-bilayer structures (shown in center), and three proteins expressed on small EVs called exosomes (shown in red, green, blue

Updated on: February 23,2024

Previously unidentified proteins suggest new way to diagnose ovarian cancer

by Nagoya UniversityExtracellular vesicles (EVs) are vesicles with lipid-bilayer structures (shown in center), and three proteins expressed on small EVs called exosomes (shown in red, green, blue

Updated on:February 23,2024