Study offers way to increase immune checkpoint inhibitor effectiveness in patients with MTAP-deleted cancers

by Dana-Farber Cancer InstituteGraphical abstract. Credit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.09.005Loss of the "housekeeping" gene methylthioadenosine phosphorylas

Updated on: February 01,2024

Study offers way to increase immune checkpoint inhibitor effectiveness in patients with MTAP-deleted cancers

by Dana-Farber Cancer InstituteGraphical abstract. Credit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.09.005Loss of the "housekeeping" gene methylthioadenosine phosphorylas

Updated on:February 01,2024

Study fingers new player in cancer immunity

by Harvard Medical SchoolKiller T cells surround a cancer cell. Credit: NIHThe immune system must strike an exquisite balance between vanquishing infections and cancer, while at the same time res

Updated on: May 25,2024

Study fingers new player in cancer immunity

by Harvard Medical SchoolKiller T cells surround a cancer cell. Credit: NIHThe immune system must strike an exquisite balance between vanquishing infections and cancer, while at the same time res

Updated on:May 25,2024

Can physical exercise enhance the effect of chemotherapy against breast cancer?

byKarolinska InstitutetSchematic presentation of published evidence regarding physical activity and breast cancer. Credit:PLOS ONE(2022). DOI: 10.1371/journal.pone.0274804Approximate

Updated on: January 07,2024

Can physical exercise enhance the effect of chemotherapy against breast cancer?

byKarolinska InstitutetSchematic presentation of published evidence regarding physical activity and breast cancer. Credit:PLOS ONE(2022). DOI: 10.1371/journal.pone.0274804Approximate

Updated on:January 07,2024

Even with multiple breast tumors, mastectomy isn't always necessary: Study

by Denise MannSome women with multiple breast tumors can safely be spared breast removal surgery, choosing less invasive treatment instead, new research suggests.Under certain conditions,women&n

Updated on: January 16,2024

Even with multiple breast tumors, mastectomy isn't always necessary: Study

by Denise MannSome women with multiple breast tumors can safely be spared breast removal surgery, choosing less invasive treatment instead, new research suggests.Under certain conditions,women&n

Updated on:January 16,2024

Researchers characterize mechanism of action of CAR T cells

by H. Lee Moffitt Cancer Center & Research InstituteScanning electron micrograph of a human T lymphocyte (also called a T cell) from the immune system of a healthy donor. Credit: NIAIDThe sci

Updated on: June 08,2024

Researchers characterize mechanism of action of CAR T cells

by H. Lee Moffitt Cancer Center & Research InstituteScanning electron micrograph of a human T lymphocyte (also called a T cell) from the immune system of a healthy donor. Credit: NIAIDThe sci

Updated on:June 08,2024

A machine learning-based algorithm to predict which cancer patients benefit from immunotherapy

by Institute for Research in Biomedicine (IRB Barcelona)Credit: CC0 Public DomainScientists at the Institute for Research in Biomedicine (IRB Barcelona), in collaboration with the Centre for Geno

Updated on: May 20,2024

A machine learning-based algorithm to predict which cancer patients benefit from immunotherapy

by Institute for Research in Biomedicine (IRB Barcelona)Credit: CC0 Public DomainScientists at the Institute for Research in Biomedicine (IRB Barcelona), in collaboration with the Centre for Geno

Updated on:May 20,2024

Team finds key to common cancer pathway

by Terry Devitt,University of Wisconsin-MadisonThe molecular pathway for the protein p53, commonly associated with many cancers, is illuminated in this micrograph. The p53 - PIP2 complex is show

Updated on: May 27,2024

Team finds key to common cancer pathway

by Terry Devitt,University of Wisconsin-MadisonThe molecular pathway for the protein p53, commonly associated with many cancers, is illuminated in this micrograph. The p53 - PIP2 complex is show

Updated on:May 27,2024

New research highlights combining prostate MRI with a blood test to avoid unnecessary prostate biopsies

by Brigham and Women’s HospitalCredit: Pixabay/CC0 Public DomainMRI of the prostate, combined with a blood test, can help determine if a prostate lesion is clinically significant cancer, new rese

Updated on: March 30,2024

New research highlights combining prostate MRI with a blood test to avoid unnecessary prostate biopsies

by Brigham and Women’s HospitalCredit: Pixabay/CC0 Public DomainMRI of the prostate, combined with a blood test, can help determine if a prostate lesion is clinically significant cancer, new rese

Updated on:March 30,2024

Technique that characterizes different immune cell groups in individual patients could revolutionize cancer treatments

by Agency for Science, Technology and Research (A*STAR), SingaporeA plot of all the different possible phenotypes of T cells before without (left) vs. with (right) immune checkpoint blockade immu

Updated on: March 01,2024

Technique that characterizes different immune cell groups in individual patients could revolutionize cancer treatments

by Agency for Science, Technology and Research (A*STAR), SingaporeA plot of all the different possible phenotypes of T cells before without (left) vs. with (right) immune checkpoint blockade immu

Updated on:March 01,2024

Novel bioassay predicts cancer patients' response to immunotherapy

byBen-Gurion University of the NegevIcAR response to fresh and fixed PDXs and generation of an IcAR score.(A) Schematic representation of the IcAR assay protocol. Following flow cytometry determ

Updated on: January 12,2024

Novel bioassay predicts cancer patients' response to immunotherapy

byBen-Gurion University of the NegevIcAR response to fresh and fixed PDXs and generation of an IcAR score.(A) Schematic representation of the IcAR assay protocol. Following flow cytometry determ

Updated on:January 12,2024

Diverse immune cell profiles and roles found in breast cancer resistance to immunotherapy

by Baylor College of MedicineDr. Xiang 'Shawn' Zhang, the corresponding author of this work. Credit: Baylor College of MedicineIn recent years it has been increasingly appreciated that im

Updated on: April 22,2024

Diverse immune cell profiles and roles found in breast cancer resistance to immunotherapy

by Baylor College of MedicineDr. Xiang 'Shawn' Zhang, the corresponding author of this work. Credit: Baylor College of MedicineIn recent years it has been increasingly appreciated that im

Updated on:April 22,2024

Family of DNA damage–inducing microbial metabolites found in guts of people with IBD

by Bob Yirka , Medical XpressHuman gut microbes isolated from IBD patients produce small-molecule genotoxins. Diverse gut microbes isolated from patients with IBD exhibit direct genotoxicity. M. morga

Updated on: February 03,2024

Family of DNA damage–inducing microbial metabolites found in guts of people with IBD

by Bob Yirka , Medical XpressHuman gut microbes isolated from IBD patients produce small-molecule genotoxins. Diverse gut microbes isolated from patients with IBD exhibit direct genotoxicity. M. morga

Updated on:February 03,2024