Understanding the role of cancer's circular genome in tumor evolution

byQueen Mary, University of LondonOverview of strategies to develop and test rules of ecDNA behavior with mathematical modeling, computer simulations, cell line and patient data. Credit:Na

Updated on: December 28,2023

Understanding the role of cancer's circular genome in tumor evolution

byQueen Mary, University of LondonOverview of strategies to develop and test rules of ecDNA behavior with mathematical modeling, computer simulations, cell line and patient data. Credit:Na

Updated on:December 28,2023

Researchers discover crucial step in creating blood stem cells

by Iowa State UniversityBlood stem cells show forming in the trunk of a zebrafish embryo. The blood stem cells are yellow, with the red tubes are the aorta on the top and a vein on the bottom. Cr

Updated on: February 03,2024

Researchers discover crucial step in creating blood stem cells

by Iowa State UniversityBlood stem cells show forming in the trunk of a zebrafish embryo. The blood stem cells are yellow, with the red tubes are the aorta on the top and a vein on the bottom. Cr

Updated on:February 03,2024

Beating cancer-related fatigue with personalized interventions

byUniversity of TwenteFlow diagram of selection of eligible studies. Credit:European Journal of Cancer Care(2022). DOI: 10.1111/ecc.13754After diagnosis and treatment of breast cance

Updated on: January 07,2024

Beating cancer-related fatigue with personalized interventions

byUniversity of TwenteFlow diagram of selection of eligible studies. Credit:European Journal of Cancer Care(2022). DOI: 10.1111/ecc.13754After diagnosis and treatment of breast cance

Updated on:January 07,2024

Illuminating tumor cells with dark proteins

by Columbia UniversityRibosome roadblock effect: comparing the AMD1 tail sequence, poly(A) and the XBP1 stalling sequence. a–e, Reporter constructs shown on the left were transfected into HEK293T

Updated on: February 19,2024

Illuminating tumor cells with dark proteins

by Columbia UniversityRibosome roadblock effect: comparing the AMD1 tail sequence, poly(A) and the XBP1 stalling sequence. a–e, Reporter constructs shown on the left were transfected into HEK293T

Updated on:February 19,2024

New biomarker for early prediction of response to CAR-T cell therapy

by Medical University of ViennaCredit: AI-generated imageA MedUni Vienna research team has discovered a highly potent biomarker for clinical response to CAR-T cell therapy, describing the prerequ

Updated on: February 01,2024

New biomarker for early prediction of response to CAR-T cell therapy

by Medical University of ViennaCredit: AI-generated imageA MedUni Vienna research team has discovered a highly potent biomarker for clinical response to CAR-T cell therapy, describing the prerequ

Updated on:February 01,2024

Seeking microscopic clues to beating deadly brain tumors

by Hackensack Meridian HealthH&E stained sections of patient glioblastoma samples. Higher magnifcation of representative regions are shown in the colored boxes. Histologic features include low (bl

Updated on: January 23,2024

Seeking microscopic clues to beating deadly brain tumors

by Hackensack Meridian HealthH&E stained sections of patient glioblastoma samples. Higher magnifcation of representative regions are shown in the colored boxes. Histologic features include low (bl

Updated on:January 23,2024

New report finds smoking rates, alcohol use, physical inactivity decreased during COVID-19

byAmerican Cancer SocietyNew ACS Report. Credit: American Cancer SocietyIn a new report, American Cancer Society (ACS) researchers discovered both favorable and unfavorable changes in major canc

Updated on: January 11,2024

New report finds smoking rates, alcohol use, physical inactivity decreased during COVID-19

byAmerican Cancer SocietyNew ACS Report. Credit: American Cancer SocietyIn a new report, American Cancer Society (ACS) researchers discovered both favorable and unfavorable changes in major canc

Updated on:January 11,2024

Researchers develop a study model for Ewing sarcoma in the Drosophila fly

by Institute for Research in Biomedicine (IRB Barcelona)EWS-FLI1FSinduces epithelial malignant tumors in the developing wing discs. Wing imaginal disc from a wild-type third instar larvae (

Updated on: February 20,2024

Researchers develop a study model for Ewing sarcoma in the Drosophila fly

by Institute for Research in Biomedicine (IRB Barcelona)EWS-FLI1FSinduces epithelial malignant tumors in the developing wing discs. Wing imaginal disc from a wild-type third instar larvae (

Updated on:February 20,2024

Study reveals somatic mutation profile of colorectal tumor with simultaneous APC and MLH1 germline mutations

by Zhao Weiwei; Hong Bo, Hefei Institutes of Physical Science, Chinese Academy of SciencesThe pedigree of the studied family, and hematoxylin-eosin staining of colorectal adenocarcinoma or adenomas in

Updated on: February 20,2024

Study reveals somatic mutation profile of colorectal tumor with simultaneous APC and MLH1 germline mutations

by Zhao Weiwei; Hong Bo, Hefei Institutes of Physical Science, Chinese Academy of SciencesThe pedigree of the studied family, and hematoxylin-eosin staining of colorectal adenocarcinoma or adenomas in

Updated on:February 20,2024

Study links mutations in notch gene to role in B cell cancers

by Perelman School of Medicine at the University of PennsylvaniaPeripheral blood with chronic lymphocytic leukemia cells. Credit: Jon Aster, Harvard Medical SchoolNotch is one of the most frequen

Updated on: July 02,2024

Study links mutations in notch gene to role in B cell cancers

by Perelman School of Medicine at the University of PennsylvaniaPeripheral blood with chronic lymphocytic leukemia cells. Credit: Jon Aster, Harvard Medical SchoolNotch is one of the most frequen

Updated on:July 02,2024

Ancient viruses could help kill cancers

by The Francis Crick InstituteHeatmap showing expression of melanoma-specific transcripts across a range of cancer types. The three columns with high expression are from melanoma samples. Credit:

Updated on: March 30,2024

Ancient viruses could help kill cancers

by The Francis Crick InstituteHeatmap showing expression of melanoma-specific transcripts across a range of cancer types. The three columns with high expression are from melanoma samples. Credit:

Updated on:March 30,2024

Study sheds light on the function of a long-mysterious PCSK9 mutation

by American Society for Biochemistry and Molecular BiologyCredit: CC0 Public DomainHigh levels of low-density lipoproteins, parcels of lipids and protein that carry cholesterol, are a leading ris

Updated on: April 18,2024

Study sheds light on the function of a long-mysterious PCSK9 mutation

by American Society for Biochemistry and Molecular BiologyCredit: CC0 Public DomainHigh levels of low-density lipoproteins, parcels of lipids and protein that carry cholesterol, are a leading ris

Updated on:April 18,2024