First test of anti-cancer agent PAC-1 in human clinical trials shows promise

by Diana Yates,University of Illinois at Urbana-ChampaignProcaspase-3 (PC-3) expressions in diverse tumor histologies categorized as moderate-to-strong immunostaining intensities. Credit:B

Updated on: December 27,2023

First test of anti-cancer agent PAC-1 in human clinical trials shows promise

by Diana Yates,University of Illinois at Urbana-ChampaignProcaspase-3 (PC-3) expressions in diverse tumor histologies categorized as moderate-to-strong immunostaining intensities. Credit:B

Updated on:December 27,2023

Selpercatinib Significantly Improves PFS, Responses in Advanced RET+ Medullary Thyroid Cancer

October 21, 2023Gina MauroSelpercatinib resulted in a statistically significant improvement in progression-free survival and overall response rate compared with cabozantinib or vandetanib in patients

Updated on: October 24,2023

Selpercatinib Significantly Improves PFS, Responses in Advanced RET+ Medullary Thyroid Cancer

October 21, 2023Gina MauroSelpercatinib resulted in a statistically significant improvement in progression-free survival and overall response rate compared with cabozantinib or vandetanib in patients

Updated on:October 24,2023

Survey: Most women unaware of the signs of an aggressive form of breast cancer

by Ohio State University Comprehensive Cancer CenterDr. Ko Un Park consults with a patient at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Sol

Updated on: December 20,2023

Survey: Most women unaware of the signs of an aggressive form of breast cancer

by Ohio State University Comprehensive Cancer CenterDr. Ko Un Park consults with a patient at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Sol

Updated on:December 20,2023

Silent cancers: Here's what you need to know when there are no obvious symptoms

by Justin Stebbing,The ConversationCredit: Pixabay/CC0 Public DomainThe recent revelations about the Princess of Wales'scancer diagnosishighlight a crucial aspect of cancer detec

Updated on: April 06,2024

Silent cancers: Here's what you need to know when there are no obvious symptoms

by Justin Stebbing,The ConversationCredit: Pixabay/CC0 Public DomainThe recent revelations about the Princess of Wales'scancer diagnosishighlight a crucial aspect of cancer detec

Updated on:April 06,2024

Immunotherapy may become new first line treatment in some metastatic colorectal cancers

byEuropean Society for Medical OncologyCancer—Histopathologic image of colonic carcinoid. Credit: Wikipedia/CC BY-SA 3.0Immunotherapy with nivolumab and low-dose ipilimumab could become a new fi

Updated on: December 18,2023

Immunotherapy may become new first line treatment in some metastatic colorectal cancers

byEuropean Society for Medical OncologyCancer—Histopathologic image of colonic carcinoid. Credit: Wikipedia/CC BY-SA 3.0Immunotherapy with nivolumab and low-dose ipilimumab could become a new fi

Updated on:December 18,2023

HDAC6 score found to predict the response of some cancers to ricolinostat

by Bob Yirka , Medical XpressHDAC6 score in BC. (a) The number of samples and dataset of origin used to evaluate the HDAC6 regulon. (b) Overlap of the original and updated HDAC6 regulons. P value was

Updated on: December 21,2023

HDAC6 score found to predict the response of some cancers to ricolinostat

by Bob Yirka , Medical XpressHDAC6 score in BC. (a) The number of samples and dataset of origin used to evaluate the HDAC6 regulon. (b) Overlap of the original and updated HDAC6 regulons. P value was

Updated on:December 21,2023

Cardiopulmonary fitness is key for helping breast cancer patients manage post-diagnosis symptoms, say researchers

by Adrianna MacPherson,University of AlbertaIndependent associations between health-related fitness variables and breast cancer-related symptoms in newly diagnosed breast cancer patients. (A) Mo

Updated on: October 26,2024

Cardiopulmonary fitness is key for helping breast cancer patients manage post-diagnosis symptoms, say researchers

by Adrianna MacPherson,University of AlbertaIndependent associations between health-related fitness variables and breast cancer-related symptoms in newly diagnosed breast cancer patients. (A) Mo

Updated on:October 26,2024

Multicancer early detection feasible for outpatients

A blood-based multicancer early detection (MCED) test using cell-free DNA (cfDNA) is feasible for outpatients and has a positive predictive value of about 40 percent, according to a study presented at

Updated on: December 21,2023

Multicancer early detection feasible for outpatients

A blood-based multicancer early detection (MCED) test using cell-free DNA (cfDNA) is feasible for outpatients and has a positive predictive value of about 40 percent, according to a study presented at

Updated on:December 21,2023

New insights into the drivers of glioma-related epilepsy

by Graciela Gutierrez,Baylor College of MedicineGraphical abstract. Credit:Neuron(2023). DOI: 10.1016/j.neuron.2023.01.013Glioma is one of the most aggressive malignant primary brain

Updated on: December 20,2023

New insights into the drivers of glioma-related epilepsy

by Graciela Gutierrez,Baylor College of MedicineGraphical abstract. Credit:Neuron(2023). DOI: 10.1016/j.neuron.2023.01.013Glioma is one of the most aggressive malignant primary brain

Updated on:December 20,2023

Team learns how to predict triple negative breast cancer recurrence

byIndiana University School of MedicineCredit: Anna CarreraIndiana University School of Medicine researchers have discovered how to predict whether triple negative breast cancer will recur, and

Updated on: December 22,2023

Team learns how to predict triple negative breast cancer recurrence

byIndiana University School of MedicineCredit: Anna CarreraIndiana University School of Medicine researchers have discovered how to predict whether triple negative breast cancer will recur, and

Updated on:December 22,2023

Researchers identify an Achilles' heel in neuroblastoma

by Molly Chiu,Baylor College of MedicineThe image shows magnified neuroblastoma cells. Credit: Baylor College of MedicineNeuroblastoma, a childhood cancer that develops from neural cells on the

Updated on: December 18,2023

Researchers identify an Achilles' heel in neuroblastoma

by Molly Chiu,Baylor College of MedicineThe image shows magnified neuroblastoma cells. Credit: Baylor College of MedicineNeuroblastoma, a childhood cancer that develops from neural cells on the

Updated on:December 18,2023

Improving treatment for hairy cell leukemia

by Melissa Rohman,Northwestern UniversityCredit: Unsplash/CC0 Public DomainPatients with relapsed or refractory hairy cell leukemia who were treated with vemurafenib experienced excellent respon

Updated on: December 22,2023

Improving treatment for hairy cell leukemia

by Melissa Rohman,Northwestern UniversityCredit: Unsplash/CC0 Public DomainPatients with relapsed or refractory hairy cell leukemia who were treated with vemurafenib experienced excellent respon

Updated on:December 22,2023