Characterization of mutational 'coldspots' in the cancer genome

byInstitute for Research in Biomedicine (IRB Barcelona)Credit: Pixabay/CC0 Public DomainMutations are the changes in the DNA that gradually occur in human cells as they replicate, and the organi

Updated on: April 28,2024

Characterization of mutational 'coldspots' in the cancer genome

byInstitute for Research in Biomedicine (IRB Barcelona)Credit: Pixabay/CC0 Public DomainMutations are the changes in the DNA that gradually occur in human cells as they replicate, and the organi

Updated on:April 28,2024

Software improves the ability to pinpoint specific genetic mutations that drive cancer

by Colin Poitras,Yale UniversityCredit: Unsplash/CC0 Public DomainA new open-source software package calledcancereffectsizeRdeveloped by the Townsend Lab greatly improves the ability

Updated on: January 03,2024

Software improves the ability to pinpoint specific genetic mutations that drive cancer

by Colin Poitras,Yale UniversityCredit: Unsplash/CC0 Public DomainA new open-source software package calledcancereffectsizeRdeveloped by the Townsend Lab greatly improves the ability

Updated on:January 03,2024

Natural mechanism causes 50-fold increase in T-cell activation sensitivity

byLatrobe UniversityThymic cortical T cell deletion induced by a CDR3 cysteine. TCR-retrogenic mice expressing the 6218 or 6218αC TCR were made as described in Fig.1, except that all recip

Updated on: January 22,2024

Natural mechanism causes 50-fold increase in T-cell activation sensitivity

byLatrobe UniversityThymic cortical T cell deletion induced by a CDR3 cysteine. TCR-retrogenic mice expressing the 6218 or 6218αC TCR were made as described in Fig.1, except that all recip

Updated on:January 22,2024

Benefits of running in the cold outweigh warm weather running, says expert

by Midwest Orthopaedics at RUSHCredit: CC0 Public DomainSome year-round runners dread plunging temperatures, but according to recent research, the benefits of running in the cold weather outweigh warm

Updated on: April 01,2024

Benefits of running in the cold outweigh warm weather running, says expert

by Midwest Orthopaedics at RUSHCredit: CC0 Public DomainSome year-round runners dread plunging temperatures, but according to recent research, the benefits of running in the cold weather outweigh warm

Updated on:April 01,2024

One million children lose mother to cancer a year: research

Credit: Pixabay/CC0 Public DomainAround one million children worldwide lose their mother to cancer every year, often leaving orphans caught up in a "vicious cycle of disadvantage", researche

Updated on: January 30,2024

One million children lose mother to cancer a year: research

Credit: Pixabay/CC0 Public DomainAround one million children worldwide lose their mother to cancer every year, often leaving orphans caught up in a "vicious cycle of disadvantage", researche

Updated on:January 30,2024

Predicting immunotherapy response and guiding combination therapy with MOTIF

byScience China PressWorkflow of MOTIF and three main application including cellular function analysis, immunotherapy response prediction and combinational therapy guidance. Credit: Science Chin

Updated on: March 30,2024

Predicting immunotherapy response and guiding combination therapy with MOTIF

byScience China PressWorkflow of MOTIF and three main application including cellular function analysis, immunotherapy response prediction and combinational therapy guidance. Credit: Science Chin

Updated on:March 30,2024

Differences found in how doctors, caregivers and patients report side effects of cancer therapy

by Children's Hospital Los AngelesCredit: CC0 Public DomainA recent study reveals differences in how symptom toxicity is reported for children receiving cancer treatment in clinical trials. D

Updated on: February 03,2024

Differences found in how doctors, caregivers and patients report side effects of cancer therapy

by Children's Hospital Los AngelesCredit: CC0 Public DomainA recent study reveals differences in how symptom toxicity is reported for children receiving cancer treatment in clinical trials. D

Updated on:February 03,2024

Researchers review the role of integrins in human hepatocellular carcinoma

by Cactus CommunicationsIn a recent review article, researchers summarize the roles integrins play in cancer cells and the current status of anti-integrin therapy for cancer. As a family of unique tra

Updated on: January 30,2024

Researchers review the role of integrins in human hepatocellular carcinoma

by Cactus CommunicationsIn a recent review article, researchers summarize the roles integrins play in cancer cells and the current status of anti-integrin therapy for cancer. As a family of unique tra

Updated on:January 30,2024

Cherenkov color imaging shows promise in enhancing radiation therapy effectiveness

bySPIEA three-channel camera separates Cherenkov emissions into red, green, and blue channels, allowing the investigation of the impact of variations in melanin and blood levels on the signal. T

Updated on: January 02,2024

Cherenkov color imaging shows promise in enhancing radiation therapy effectiveness

bySPIEA three-channel camera separates Cherenkov emissions into red, green, and blue channels, allowing the investigation of the impact of variations in melanin and blood levels on the signal. T

Updated on:January 02,2024

Researchers find out why some lung tumors avoid immunotherapy, and learn how to predict this in advance

by Josep Carreras Leukaemia Research InstituteGraphical abstract. Credit:Cell Reports Medicine(2023). DOI: 10.1016/j.xcrm.2023.101006The oncogenic activation of MYC, a critical gene i

Updated on: February 18,2024

Researchers find out why some lung tumors avoid immunotherapy, and learn how to predict this in advance

by Josep Carreras Leukaemia Research InstituteGraphical abstract. Credit:Cell Reports Medicine(2023). DOI: 10.1016/j.xcrm.2023.101006The oncogenic activation of MYC, a critical gene i

Updated on:February 18,2024

The origin-of-life molecule, a key to cancer research

byUniversity of SevilleSchematic model of the regulation and role of RNAPII-generated nascent RNA to guide DNA end resection and DSB repair by HR. Credit:Nature Communications(2022).

Updated on: January 04,2024

The origin-of-life molecule, a key to cancer research

byUniversity of SevilleSchematic model of the regulation and role of RNAPII-generated nascent RNA to guide DNA end resection and DSB repair by HR. Credit:Nature Communications(2022).

Updated on:January 04,2024

Body mass index tied to multiple myeloma survival

by Lori SolomonUnderweight and severe obesity are associated with decreased survival in patients with multiple myeloma (MM), according to a study published online Jan. 12 in theBlood Cancer Jour

Updated on: January 07,2024

Body mass index tied to multiple myeloma survival

by Lori SolomonUnderweight and severe obesity are associated with decreased survival in patients with multiple myeloma (MM), according to a study published online Jan. 12 in theBlood Cancer Jour

Updated on:January 07,2024