Mechanism facilitates brain metastasis from breast cancer and melanoma by inducing neuroinflammation

byTel-Aviv UniversityBrain metastatic burden and survival in mice injected with breast cancer cells. a. Experimental scheme analyzed in (b,c). b. Survival curve analysis of WT and Lcn2-/-m

Updated on: January 07,2024

Mechanism facilitates brain metastasis from breast cancer and melanoma by inducing neuroinflammation

byTel-Aviv UniversityBrain metastatic burden and survival in mice injected with breast cancer cells. a. Experimental scheme analyzed in (b,c). b. Survival curve analysis of WT and Lcn2-/-m

Updated on:January 07,2024

An intelligent knife can tell ovarian cancer and healthy tissue apart. Could it make surgery smarter?

by Katie Roberts,Cancer Research UKTesting the iKnife in the lab. Credit: Cancer Research UKSurgery is a major part of ovarian cancer treatment, but it can be a blunt tool.A big problem for surg

Updated on: April 09,2024

An intelligent knife can tell ovarian cancer and healthy tissue apart. Could it make surgery smarter?

by Katie Roberts,Cancer Research UKTesting the iKnife in the lab. Credit: Cancer Research UKSurgery is a major part of ovarian cancer treatment, but it can be a blunt tool.A big problem for surg

Updated on:April 09,2024

'Cancer-blocking' protein offers potential to transform cells from destructive to constructive

byAustralian National UniversityNLRC4 attenuates tumor development inApcmin/+mice. Credit:Nature Immunology(2024). DOI: 10.1038/s41590-024-01988-6An immune protein could

Updated on: November 10,2024

'Cancer-blocking' protein offers potential to transform cells from destructive to constructive

byAustralian National UniversityNLRC4 attenuates tumor development inApcmin/+mice. Credit:Nature Immunology(2024). DOI: 10.1038/s41590-024-01988-6An immune protein could

Updated on:November 10,2024

FDA Approves Two Cell-Based SCD Gene Therapies

February 2024The U.S. Food and Drug Administration (FDA) approved exagamglogene autotemcel (exa-cel) and lovotibeglogene autotemcel (lovo-cel) for the treatment of sickle cell disease (SCD) in patient

Updated on: February 18,2024

FDA Approves Two Cell-Based SCD Gene Therapies

February 2024The U.S. Food and Drug Administration (FDA) approved exagamglogene autotemcel (exa-cel) and lovotibeglogene autotemcel (lovo-cel) for the treatment of sickle cell disease (SCD) in patient

Updated on:February 18,2024

Study finds cancer cells use a new fuel in absence of sugar

by Anna Megdell,University of MichiganProfiling of metabolite utilization in PDA cells identifies uridine. Credit:Nature(2023). DOI: 10.1038/s41586-023-06073-wResearchers at the Univ

Updated on: January 23,2024

Study finds cancer cells use a new fuel in absence of sugar

by Anna Megdell,University of MichiganProfiling of metabolite utilization in PDA cells identifies uridine. Credit:Nature(2023). DOI: 10.1038/s41586-023-06073-wResearchers at the Univ

Updated on:January 23,2024

Researchers reveal role of PPDPF in development of mutant KRAS-driven pancreatic ductal adenocarcinoma

by Liu Jia,Chinese Academy of SciencesSchematic representation demonstrating the function of PPDPF in KRAS activation. Credit: Dr. XIE Dong's groupA recent study by Dr. Xie Dong's group

Updated on: February 20,2024

Researchers reveal role of PPDPF in development of mutant KRAS-driven pancreatic ductal adenocarcinoma

by Liu Jia,Chinese Academy of SciencesSchematic representation demonstrating the function of PPDPF in KRAS activation. Credit: Dr. XIE Dong's groupA recent study by Dr. Xie Dong's group

Updated on:February 20,2024

Targeted cancer drug made available for some NHS liver cancer patients

by Cancer Research UKCredit: CC0 Public DomainA targeted cancer drug will now be available for some adults with advanced liver cancer on the NHS.Regorafenib (Stivarga) is to be offered to people

Updated on: March 09,2024

Targeted cancer drug made available for some NHS liver cancer patients

by Cancer Research UKCredit: CC0 Public DomainA targeted cancer drug will now be available for some adults with advanced liver cancer on the NHS.Regorafenib (Stivarga) is to be offered to people

Updated on:March 09,2024

New delivery strategy may improve chemotherapy for acute myeloid leukemia

byWileyCNL augments the efficacy of cytarabine/venetoclax treatment in in vivo AML models. (A–C) Bioluminescence images (A), their quantification (B) and survival of MOLM-13 Luc-YFP bearing NRG

Updated on: January 11,2024

New delivery strategy may improve chemotherapy for acute myeloid leukemia

byWileyCNL augments the efficacy of cytarabine/venetoclax treatment in in vivo AML models. (A–C) Bioluminescence images (A), their quantification (B) and survival of MOLM-13 Luc-YFP bearing NRG

Updated on:January 11,2024

Study gives new insight into how cancer metastasizes to the brain

by The Wistar InstituteIFN signaling is activated in brain metastasis.a–cIFN signaling is activated in both human astrocytes and MDA231-BrM cells by coculture in vitro.N = 2 bio

Updated on: February 20,2024

Study gives new insight into how cancer metastasizes to the brain

by The Wistar InstituteIFN signaling is activated in brain metastasis.a–cIFN signaling is activated in both human astrocytes and MDA231-BrM cells by coculture in vitro.N = 2 bio

Updated on:February 20,2024

Family-focused interventions for African Americans with cancer

by Amy Cherry,University of DelawareCredit: Pixabay/CC0 Public DomainThe moment you're told the dreaded words: "You have cancer," your life changes forever. A parent diagnosed with

Updated on: April 28,2024

Family-focused interventions for African Americans with cancer

by Amy Cherry,University of DelawareCredit: Pixabay/CC0 Public DomainThe moment you're told the dreaded words: "You have cancer," your life changes forever. A parent diagnosed with

Updated on:April 28,2024

Targeted hope for metastatic cancer

by Paul Mayne,University of Western OntarioCancer cell during cell division. Credit: National Institutes of HealthA cancer diagnosis is tough enough to hear, but a diagnosis that cancer has spre

Updated on: April 01,2024

Targeted hope for metastatic cancer

by Paul Mayne,University of Western OntarioCancer cell during cell division. Credit: National Institutes of HealthA cancer diagnosis is tough enough to hear, but a diagnosis that cancer has spre

Updated on:April 01,2024

Immune system holds clues to patients with high-risk smoldering myeloma likely to benefit from treatment

byDana-Farber Cancer InstituteGraphical abstract. Credit:Cancer Cell(2022). DOI: 10.1016/j.ccell.2022.10.017For many patients with a condition that often precedes multiple myeloma, e

Updated on: January 02,2024

Immune system holds clues to patients with high-risk smoldering myeloma likely to benefit from treatment

byDana-Farber Cancer InstituteGraphical abstract. Credit:Cancer Cell(2022). DOI: 10.1016/j.ccell.2022.10.017For many patients with a condition that often precedes multiple myeloma, e

Updated on:January 02,2024