Tumor Sequencing Identifies Host Signatures Tied to Immunotherapy Response in Advanced RCC

July 14, 2023Caroline SeymourHigher levels of baseline TCR clonality in peripheral blood mononuclear cells (PBMCs) and baseline IgG1 fraction in PBMCs and tumor tissue were identified in an institutio

Updated on: October 24,2023

Tumor Sequencing Identifies Host Signatures Tied to Immunotherapy Response in Advanced RCC

July 14, 2023Caroline SeymourHigher levels of baseline TCR clonality in peripheral blood mononuclear cells (PBMCs) and baseline IgG1 fraction in PBMCs and tumor tissue were identified in an institutio

Updated on:October 24,2023

Cost of cancer treatment can impact health of survivors

byMedical College of Georgia at Augusta UniversityDrs. Steven Coughlin, from left, Jorge Cortes and Biplab Datta. Credit: Michael Holahan, Augusta UniversityA significant number of people who ha

Updated on: December 18,2023

Cost of cancer treatment can impact health of survivors

byMedical College of Georgia at Augusta UniversityDrs. Steven Coughlin, from left, Jorge Cortes and Biplab Datta. Credit: Michael Holahan, Augusta UniversityA significant number of people who ha

Updated on:December 18,2023

New study using novel approach for glioblastoma treatment shows promising results, extending survival

byUniversity Health NetworkAn illustration of oncolytic virus and an anti-PD-1 antibody working together to defeat cancer cells. Credit: Tal BavliA new international study published inNatu

Updated on: January 04,2024

New study using novel approach for glioblastoma treatment shows promising results, extending survival

byUniversity Health NetworkAn illustration of oncolytic virus and an anti-PD-1 antibody working together to defeat cancer cells. Credit: Tal BavliA new international study published inNatu

Updated on:January 04,2024

Comparing DNA changes in blood stem cells and leukemia cells could help pick out children with high-risk AML

Credit: Unsplash/CC0 Public DomainIn some children with acute myeloid leukemia, cancer cells have as many DNA changes as healthy blood stem cells. Researchers were surprised to find these children hav

Updated on: November 02,2023

Comparing DNA changes in blood stem cells and leukemia cells could help pick out children with high-risk AML

Credit: Unsplash/CC0 Public DomainIn some children with acute myeloid leukemia, cancer cells have as many DNA changes as healthy blood stem cells. Researchers were surprised to find these children hav

Updated on:November 02,2023

Novel therapeutic targets discovered for triple-negative breast cancer

by Melissa Rohman,Northwestern UniversityThe signature of TRIM21low/CD73highis associated with unfavorable immune response. (A) Proteomic data from CPTAC identified that the expression of

Updated on: December 21,2023

Novel therapeutic targets discovered for triple-negative breast cancer

by Melissa Rohman,Northwestern UniversityThe signature of TRIM21low/CD73highis associated with unfavorable immune response. (A) Proteomic data from CPTAC identified that the expression of

Updated on:December 21,2023

As cancer survival rates are improving, heart problems in survivors are becoming more common

by Sean Tan,Monash UniversityCredit: Pixabay/CC0 Public DomainThe soft beeping of medical devices deepens the silence of the operating theater waiting room. Lying between monitors and intravenou

Updated on: January 04,2024

As cancer survival rates are improving, heart problems in survivors are becoming more common

by Sean Tan,Monash UniversityCredit: Pixabay/CC0 Public DomainThe soft beeping of medical devices deepens the silence of the operating theater waiting room. Lying between monitors and intravenou

Updated on:January 04,2024

CYNK-101 Plus Avelumab Mediates ADCC Activity in Select PD-L1+ Solid Tumors

November 13, 2022Gina MauroCYNK-101 demonstrated synergistic activity when used in combination with avelumab through antibody-dependent cellular cytotoxicity against PD-L1–positive non–small cell lung

Updated on: October 17,2023

CYNK-101 Plus Avelumab Mediates ADCC Activity in Select PD-L1+ Solid Tumors

November 13, 2022Gina MauroCYNK-101 demonstrated synergistic activity when used in combination with avelumab through antibody-dependent cellular cytotoxicity against PD-L1–positive non–small cell lung

Updated on:October 17,2023

Can the flu shot help fight cancer?

byRush University Medical CenterCredit: CC0 Public DomainChanging the microenvironment of tumors to increase the immune system's response to them has been the goal of countless research and

Updated on: December 20,2023

Can the flu shot help fight cancer?

byRush University Medical CenterCredit: CC0 Public DomainChanging the microenvironment of tumors to increase the immune system's response to them has been the goal of countless research and

Updated on:December 20,2023

Adjuvant capecitabine after CRT improves survival in locally advanced nasopharynx

October 25, 2022Jason HarrisTreatment with adjuvant capecitabine following concurrent chemoradiotherapy resulted in superior failure-free survival compared with observation and CRT for patients with l

Updated on: October 17,2023

Adjuvant capecitabine after CRT improves survival in locally advanced nasopharynx

October 25, 2022Jason HarrisTreatment with adjuvant capecitabine following concurrent chemoradiotherapy resulted in superior failure-free survival compared with observation and CRT for patients with l

Updated on:October 17,2023

Pre- and post-surgical immunotherapy improves outcomes for patients with operable lung cancer

byUniversity of Texas M. D. Anderson Cancer CenterCredit: Pixabay/CC0 Public DomainCompared with pre-surgical (neoadjuvant) chemotherapy alone, adding perioperative immunotherapy—given before an

Updated on: October 23,2023

Pre- and post-surgical immunotherapy improves outcomes for patients with operable lung cancer

byUniversity of Texas M. D. Anderson Cancer CenterCredit: Pixabay/CC0 Public DomainCompared with pre-surgical (neoadjuvant) chemotherapy alone, adding perioperative immunotherapy—given before an

Updated on:October 23,2023

Mechanics of breast cancer metastasis discovered, offering target for treatment

Mechanics of breast cancer metastasis discovered, offering target for treatmentby Adrienne Berard,Pennsylvania State UniversityA human breast cancer cell, adenocarcinoma MDA-MB-231, demonstrates

Updated on: October 30,2023

Mechanics of breast cancer metastasis discovered, offering target for treatment

Mechanics of breast cancer metastasis discovered, offering target for treatmentby Adrienne Berard,Pennsylvania State UniversityA human breast cancer cell, adenocarcinoma MDA-MB-231, demonstrates

Updated on:October 30,2023

Lutetium Lu 177 Vipivotide Tetraxetan Provides HRQOL Benefit, Reduces Skeletal Events in mCRPC

July 9, 2023Kyle DohertyThe addition of lutetium Lu 177 vipivotide tetraxetan to standard-of-care treatment delayed time to worsening of health-related quality of life and skeletal events compared wit

Updated on: October 15,2023

Lutetium Lu 177 Vipivotide Tetraxetan Provides HRQOL Benefit, Reduces Skeletal Events in mCRPC

July 9, 2023Kyle DohertyThe addition of lutetium Lu 177 vipivotide tetraxetan to standard-of-care treatment delayed time to worsening of health-related quality of life and skeletal events compared wit

Updated on:October 15,2023