Researchers use a new approach to hit an 'undruggable' target

by University of MichiganGraphical abstract. Credit:Nature Chemical Biology(2023). DOI: 10.1038/s41589-022-01248-4The protein STAT5 has long been an appealing target against cancer, b

Updated on: February 18,2024

Researchers use a new approach to hit an 'undruggable' target

by University of MichiganGraphical abstract. Credit:Nature Chemical Biology(2023). DOI: 10.1038/s41589-022-01248-4The protein STAT5 has long been an appealing target against cancer, b

Updated on:February 18,2024

Lethal cancer cells buddy up to survive

by University of California, IrvineConsistent Metabolic Features in a Second PDA Clonal Cell Model and Media Metabolite Profiling.A. Dose response curves of oligomycin treated KPC clones 28

Updated on: February 18,2024

Lethal cancer cells buddy up to survive

by University of California, IrvineConsistent Metabolic Features in a Second PDA Clonal Cell Model and Media Metabolite Profiling.A. Dose response curves of oligomycin treated KPC clones 28

Updated on:February 18,2024

Integrated analysis finds vulnerabilities to target in a high-risk pediatric tumor

by St. Jude Children's Research HospitalElizabeth Stewart, M.D., and Hong Wang, Ph.D. of St. Jude Children's Research Hospital. Credit: St. Jude Children's Research HospitalSt. Jude C

Updated on: April 01,2024

Integrated analysis finds vulnerabilities to target in a high-risk pediatric tumor

by St. Jude Children's Research HospitalElizabeth Stewart, M.D., and Hong Wang, Ph.D. of St. Jude Children's Research Hospital. Credit: St. Jude Children's Research HospitalSt. Jude C

Updated on:April 01,2024

Cellular power-up: Stem cells provide T cells a lifeline as cancer champions

by University of Los AndesExperimental workflow of MitoT to native and CAR engineered T cells. Credit:Journal of Translational Medicine(2024). DOI: 10.1186/s12967-024-05627-4In a pioneerin

Updated on: October 24,2024

Cellular power-up: Stem cells provide T cells a lifeline as cancer champions

by University of Los AndesExperimental workflow of MitoT to native and CAR engineered T cells. Credit:Journal of Translational Medicine(2024). DOI: 10.1186/s12967-024-05627-4In a pioneerin

Updated on:October 24,2024

A calculator to predict benefit from adjuvant transarterial chemoembolization for hepatocellular carcinoma

by First Hospital of Jilin UniversityVisual Abstract. Credit: Wei-Yue Chen, Jian-Song Ji, Tian Yang, et al.Hepatocellular carcinoma (HCC) is the most commonly diagnosed cancer of the liver and the fou

Updated on: February 20,2024

A calculator to predict benefit from adjuvant transarterial chemoembolization for hepatocellular carcinoma

by First Hospital of Jilin UniversityVisual Abstract. Credit: Wei-Yue Chen, Jian-Song Ji, Tian Yang, et al.Hepatocellular carcinoma (HCC) is the most commonly diagnosed cancer of the liver and the fou

Updated on:February 20,2024

Researchers use machine learning to unlock the genomic code in clinical cancer samples

by University of HelsinkiMutational signatures of formalin exposure. a C>T FFPE-only mutation count increases with formalin fixation time. We observed this increase in both unrepaired and repa

Updated on: February 18,2024

Researchers use machine learning to unlock the genomic code in clinical cancer samples

by University of HelsinkiMutational signatures of formalin exposure. a C>T FFPE-only mutation count increases with formalin fixation time. We observed this increase in both unrepaired and repa

Updated on:February 18,2024

Researchers use AI to understand lung cancer cell vulnerabilities

by University of MontanaMark Grimes, a researcher and University of Montana biology professor, uses AI to learn more about lung cancer vulnerabilities. Credit: University of Montana photo by Tomm

Updated on: February 18,2024

Researchers use AI to understand lung cancer cell vulnerabilities

by University of MontanaMark Grimes, a researcher and University of Montana biology professor, uses AI to learn more about lung cancer vulnerabilities. Credit: University of Montana photo by Tomm

Updated on:February 18,2024

New AI-based biomarker can help predict immunotherapy response for patients with lung cancer

byEmory UniversityResponder tumor to ICI has less tortuous vessel branches compared to nonresponder. (A and B) CT scans of a responder and nonresponder to IO with corresponding 3D rendering of t

Updated on: January 12,2024

New AI-based biomarker can help predict immunotherapy response for patients with lung cancer

byEmory UniversityResponder tumor to ICI has less tortuous vessel branches compared to nonresponder. (A and B) CT scans of a responder and nonresponder to IO with corresponding 3D rendering of t

Updated on:January 12,2024

A new approach to targeting tumors and tracking their spread

by Massachusetts Institute of TechnologyKiller T cells surround a cancer cell. Credit: NIHThe spread of malignant cells from an original tumor to other parts of the body, known as metastasis, is

Updated on: May 20,2024

A new approach to targeting tumors and tracking their spread

by Massachusetts Institute of TechnologyKiller T cells surround a cancer cell. Credit: NIHThe spread of malignant cells from an original tumor to other parts of the body, known as metastasis, is

Updated on:May 20,2024

Biomarkers show promise for identifying early risk of pancreatic cancer

byDuke University Medical CenterCredit: Pixabay/CC0 Public DomainA research team at Duke Health has identified a set of biomarkers that could help distinguish whether cysts on the pancreas are l

Updated on: January 04,2024

Biomarkers show promise for identifying early risk of pancreatic cancer

byDuke University Medical CenterCredit: Pixabay/CC0 Public DomainA research team at Duke Health has identified a set of biomarkers that could help distinguish whether cysts on the pancreas are l

Updated on:January 04,2024

Researchers discover how to predict the efficacy of one of the most widely used drugs against breast cancer

by The Spanish National Cancer Research CentreClinical trial tumor samples: the phosphoprofiles were independent of the study site and/or treatment arm.AClinical trial treatment and s

Updated on: February 18,2024

Researchers discover how to predict the efficacy of one of the most widely used drugs against breast cancer

by The Spanish National Cancer Research CentreClinical trial tumor samples: the phosphoprofiles were independent of the study site and/or treatment arm.AClinical trial treatment and s

Updated on:February 18,2024

Real-world data suggests stopping immunotherapy after two years is reasonable in patients with advanced lung cancer

byPerelman School of Medicine at the University of PennsylvaniaCredit: Pixabay/CC0 Public DomainOver the past decade, the approval of immune checkpoint inhibitors has revolutionized treatment fo

Updated on: January 04,2024

Real-world data suggests stopping immunotherapy after two years is reasonable in patients with advanced lung cancer

byPerelman School of Medicine at the University of PennsylvaniaCredit: Pixabay/CC0 Public DomainOver the past decade, the approval of immune checkpoint inhibitors has revolutionized treatment fo

Updated on:January 04,2024