Children with resistant leukemia given CRISPR-edited T cells: Phase 1 study results reported

byUniversity College LondonAn artist’s depiction of a T cell. Credit: NIAIDResearchers at Great Ormond Street Hospital for Children (GOSH) and UCL Great Ormond Street Institute of Child Health (

Updated on: January 02,2024

Children with resistant leukemia given CRISPR-edited T cells: Phase 1 study results reported

byUniversity College LondonAn artist’s depiction of a T cell. Credit: NIAIDResearchers at Great Ormond Street Hospital for Children (GOSH) and UCL Great Ormond Street Institute of Child Health (

Updated on:January 02,2024

Combined epigenetic and immunotherapy for blastic and classical mantle cell lymphoma

by Impact JournalsMechanisms of SCR resistance and characterization of the CD20 negative MCL cell lines 353. Credit: LeBlanc et al,Oncotarget(2022). DOI: 10.18632/oncotarget.28258A new res

Updated on: January 02,2024

Combined epigenetic and immunotherapy for blastic and classical mantle cell lymphoma

by Impact JournalsMechanisms of SCR resistance and characterization of the CD20 negative MCL cell lines 353. Credit: LeBlanc et al,Oncotarget(2022). DOI: 10.18632/oncotarget.28258A new res

Updated on:January 02,2024

New mathematical model shows promising results for prostate cancer treatment

byUniversity of PortsmouthGraphical abstract. Credit:Mathematical Biosciences(2022). DOI: 10.1016/j.mbs.2022.108940A new mathematical model which aims to optimize treatment for prost

Updated on: January 12,2024

New mathematical model shows promising results for prostate cancer treatment

byUniversity of PortsmouthGraphical abstract. Credit:Mathematical Biosciences(2022). DOI: 10.1016/j.mbs.2022.108940A new mathematical model which aims to optimize treatment for prost

Updated on:January 12,2024

Researchers discover new pathways to activate dendritic cells, produce strong anti-tumor immunity

by H. Lee Moffitt Cancer Center & Research InstituteArtistic rendering of the surface of a human dendritic cell illustrating sheet-like processes that fold back onto the membrane surface. Cre

Updated on: January 30,2024

Researchers discover new pathways to activate dendritic cells, produce strong anti-tumor immunity

by H. Lee Moffitt Cancer Center & Research InstituteArtistic rendering of the surface of a human dendritic cell illustrating sheet-like processes that fold back onto the membrane surface. Cre

Updated on:January 30,2024

Immune checkpoint blockade prior to surgery promising in multiple cancer types, finds study

byJohns Hopkins University School of MedicineThis graphic highlights the vast scientific research opportunities associated with neoadjuvant immune checkpoint blockade. Credit:Cancer CellTr

Updated on: January 23,2024

Immune checkpoint blockade prior to surgery promising in multiple cancer types, finds study

byJohns Hopkins University School of MedicineThis graphic highlights the vast scientific research opportunities associated with neoadjuvant immune checkpoint blockade. Credit:Cancer CellTr

Updated on:January 23,2024

A new tumor-suppressive gene that boosts personalized treatment response in breast cancer

by The University of Hong KongGraphical Abstract. Credit:Cell Reports(2022). DOI: 10.1016/j.celrep.2022.111821A research team from LKS Faculty of Medicine, the University of Hong Kong

Updated on: January 30,2024

A new tumor-suppressive gene that boosts personalized treatment response in breast cancer

by The University of Hong KongGraphical Abstract. Credit:Cell Reports(2022). DOI: 10.1016/j.celrep.2022.111821A research team from LKS Faculty of Medicine, the University of Hong Kong

Updated on:January 30,2024

Team identifies the cells responsible for colon cancer relapse

by Institute for Research in Biomedicine (IRB Barcelona)Colorectal cancer organoids, edited to express a tdTomato reporter in cells with high Epithelial membrane protein 1 (Emp1) expression, were

Updated on: February 03,2024

Team identifies the cells responsible for colon cancer relapse

by Institute for Research in Biomedicine (IRB Barcelona)Colorectal cancer organoids, edited to express a tdTomato reporter in cells with high Epithelial membrane protein 1 (Emp1) expression, were

Updated on:February 03,2024

Researchers find possible cause for chemoresistance in bowel cancer

by Martin-Luther-Universität Halle-WittenbergAnalysis of IGF2BP2 targets in tumor and metastatic CRC tissues. A, B Cumulative plot of gene expression (log2 fold change) in primary (A) and metastatic (

Updated on: January 30,2024

Researchers find possible cause for chemoresistance in bowel cancer

by Martin-Luther-Universität Halle-WittenbergAnalysis of IGF2BP2 targets in tumor and metastatic CRC tissues. A, B Cumulative plot of gene expression (log2 fold change) in primary (A) and metastatic (

Updated on:January 30,2024

Study finds that brain tumors 'hack' the communication between neurons

byThe Spanish National Cancer Research CentreThe metastasis (lighter green) is shown to interact with a neuron (brighter green). This neuron has been artificially marked for research, but is sur

Updated on: January 23,2024

Study finds that brain tumors 'hack' the communication between neurons

byThe Spanish National Cancer Research CentreThe metastasis (lighter green) is shown to interact with a neuron (brighter green). This neuron has been artificially marked for research, but is sur

Updated on:January 23,2024

Deadly 'two-faced' protein drives cancer growth, cripples T-cell avengers

by Delthia Ricks , Medical XpressScanning electron micrograph of a human T lymphocyte (also called a T cell) from the immune system of a healthy donor. Credit: NIAIDScientists have deciphered a key st

Updated on: April 09,2024

Deadly 'two-faced' protein drives cancer growth, cripples T-cell avengers

by Delthia Ricks , Medical XpressScanning electron micrograph of a human T lymphocyte (also called a T cell) from the immune system of a healthy donor. Credit: NIAIDScientists have deciphered a key st

Updated on:April 09,2024

Researchers identify targeted therapy that can help children with deadly nerve cancer

by The Mount Sinai HospitalCredit: CC0 Public DomainMount Sinai researchers have identified a targeted therapy for adolescent patients with neuroblastoma, a deadly pediatric nerve cancer, who wou

Updated on: June 08,2024

Researchers identify targeted therapy that can help children with deadly nerve cancer

by The Mount Sinai HospitalCredit: CC0 Public DomainMount Sinai researchers have identified a targeted therapy for adolescent patients with neuroblastoma, a deadly pediatric nerve cancer, who wou

Updated on:June 08,2024

ASCT may offer alternative for therapy for high-risk follicular lymphoma

(HealthDay)—Autologous stem cell transplantation (ASCT) may be an effective treatment option in high-risk, early therapy failure (ETF) follicular lymphoma (FL), prior to the use of rituximab, accordin

Updated on: March 30,2024

ASCT may offer alternative for therapy for high-risk follicular lymphoma

(HealthDay)—Autologous stem cell transplantation (ASCT) may be an effective treatment option in high-risk, early therapy failure (ETF) follicular lymphoma (FL), prior to the use of rituximab, accordin

Updated on:March 30,2024