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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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Repurposing heart drugs to target cancer cells

Repurposing heart drugs to target cancer cells

by MRC London Institute of Medical SciencesCredit: CC0 Public DomainSenescence is a cellular stress response that results in the stable growth arrest of old and damaged cells. The past decade has reve

Repurposing heart drugs to target cancer cells

by MRC London Institute of Medical SciencesCredit: CC0 Public DomainSenescence is a cellular stress response that results in the stable growth arrest of old and damaged cells. The past decade has reve
Potential therapeutic target for small cell lung cancer discovered

Potential therapeutic target for small cell lung cancer discovered

by Melissa Rohman,Northwestern UniversityGraphic model showing how POU2AF2 establishes the poised enhancer via SWI/SNF activity-dependent recruitment of the Polycomb complex in SCLC-P subtype ce

Potential therapeutic target for small cell lung cancer discovered

by Melissa Rohman,Northwestern UniversityGraphic model showing how POU2AF2 establishes the poised enhancer via SWI/SNF activity-dependent recruitment of the Polycomb complex in SCLC-P subtype ce
Novel therapeutic strategy against melanoma: Combined targeting of hedgehog signaling and BRD4

Novel therapeutic strategy against melanoma: Combined targeting of hedgehog signaling and BRD4

by Impact Journals LLCCombined targeting of SMO and BRD4 as a potential therapeutic strategy against melanoma. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.28441A new editorial paper

Novel therapeutic strategy against melanoma: Combined targeting of hedgehog signaling and BRD4

by Impact Journals LLCCombined targeting of SMO and BRD4 as a potential therapeutic strategy against melanoma. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.28441A new editorial paper
Aerobic activity can reduce the risk of metastatic cancer by 72%

Aerobic activity can reduce the risk of metastatic cancer by 72%

by Tel Aviv UniversityCredit: Pixabay/CC0 Public DomainA new study at Tel Aviv University found that aerobic exercise can reduce the risk of metastatic cancer by 72%. According to the researchers

Aerobic activity can reduce the risk of metastatic cancer by 72%

by Tel Aviv UniversityCredit: Pixabay/CC0 Public DomainA new study at Tel Aviv University found that aerobic exercise can reduce the risk of metastatic cancer by 72%. According to the researchers
Synthetic molecule proves able to mitigate heart failure in translational study

Synthetic molecule proves able to mitigate heart failure in translational study

by Maria Fernanda Ziegler,FAPESPThe vicious cycle of heart failure (HF). (i) Impaired aldehyde metabolism by aldehyde dehydrogenase 2 (ALDH2); (ii) accumulation of 4-hydroxynonenal (4-HNE), a re

Synthetic molecule proves able to mitigate heart failure in translational study

by Maria Fernanda Ziegler,FAPESPThe vicious cycle of heart failure (HF). (i) Impaired aldehyde metabolism by aldehyde dehydrogenase 2 (ALDH2); (ii) accumulation of 4-hydroxynonenal (4-HNE), a re
Study overturns dogma of cancer metabolism theory

Study overturns dogma of cancer metabolism theory

by University of California, Los AngelesImage shows squamous cell skin cancer tumors with lactate production (a byproduct of glucose consumption) in purple. The tumor with lactate production bloc

Study overturns dogma of cancer metabolism theory

by University of California, Los AngelesImage shows squamous cell skin cancer tumors with lactate production (a byproduct of glucose consumption) in purple. The tumor with lactate production bloc
Malpractice trends involving active surveillance across cancers

Malpractice trends involving active surveillance across cancers

by Cedars-Sinai Medical CenterCredit: CC0 Public DomainActive surveillance is an established practice for managing certain low-risk cancers that are unlikely to cause harm. It is an increasingly

Malpractice trends involving active surveillance across cancers

by Cedars-Sinai Medical CenterCredit: CC0 Public DomainActive surveillance is an established practice for managing certain low-risk cancers that are unlikely to cause harm. It is an increasingly
Researcher and her students discover lesser-known gene associated with breast cancer

Researcher and her students discover lesser-known gene associated with breast cancer

by Villanova UniversityCredit: Villanova UniversityVillanova University biology professor Janice Knepper, PhD, and her students have discovered that a gene, previously poorly characterized, can b

Researcher and her students discover lesser-known gene associated with breast cancer

by Villanova UniversityCredit: Villanova UniversityVillanova University biology professor Janice Knepper, PhD, and her students have discovered that a gene, previously poorly characterized, can b
Genetic test could help fight secondary breast cancer

Genetic test could help fight secondary breast cancer

by University of SheffieldMammograms showing a normal breast (left) and a breast with cancer (right). Credit: Public DomainThousands of breast cancer patients at risk of developing aggressive sec

Genetic test could help fight secondary breast cancer

by University of SheffieldMammograms showing a normal breast (left) and a breast with cancer (right). Credit: Public DomainThousands of breast cancer patients at risk of developing aggressive sec
Researcher: Big data, networks identify cell signaling pathways in lung cancer

Researcher: Big data, networks identify cell signaling pathways in lung cancer

by University of MontanaThe cover of the May 22 issue ofScience Signalingfeatures a three-dimensional representation of lung cancer protein modifications produced by the machine learn

Researcher: Big data, networks identify cell signaling pathways in lung cancer

by University of MontanaThe cover of the May 22 issue ofScience Signalingfeatures a three-dimensional representation of lung cancer protein modifications produced by the machine learn
Novel AI tools tackle soft tissue sarcomas, identify new treatment strategies

Novel AI tools tackle soft tissue sarcomas, identify new treatment strategies

byStanford University Medical CenterA machine-learning framework for large-scale identification and validation of sarcoma cell states and ecosystems. Credit:Nature Cancer(2024). DOI:

Novel AI tools tackle soft tissue sarcomas, identify new treatment strategies

byStanford University Medical CenterA machine-learning framework for large-scale identification and validation of sarcoma cell states and ecosystems. Credit:Nature Cancer(2024). DOI:
Diverse immune cell profiles and roles found in breast cancer resistance to immunotherapy

Diverse immune cell profiles and roles found in breast cancer resistance to immunotherapy

by Baylor College of MedicineDr. Xiang 'Shawn' Zhang, the corresponding author of this work. Credit: Baylor College of MedicineIn recent years it has been increasingly appreciated that im

Diverse immune cell profiles and roles found in breast cancer resistance to immunotherapy

by Baylor College of MedicineDr. Xiang 'Shawn' Zhang, the corresponding author of this work. Credit: Baylor College of MedicineIn recent years it has been increasingly appreciated that im