Mapping oesophageal cancer genes leads to new drug targets

byCancer Research UK| News4 February 2019Mutations that cause oesophageal adenocarcinoma (OAC) have been mapped in unprecedented detail – unveiling that more than half could be targeted by

Updated on: December 19,2023

Mapping oesophageal cancer genes leads to new drug targets

byCancer Research UK| News4 February 2019Mutations that cause oesophageal adenocarcinoma (OAC) have been mapped in unprecedented detail – unveiling that more than half could be targeted by

Updated on:December 19,2023

Nab-paclitaxel does not extend biliary tract cancer survival, but may benefit some

by SWOG Cancer Research NetworkCredit: Pixabay/CC0 Public DomainAdding nab-paclitaxel to a standard treatment of gemcitabine plus cisplatin does not significantly extend median overall survival (OS) t

Updated on: December 17,2023

Nab-paclitaxel does not extend biliary tract cancer survival, but may benefit some

by SWOG Cancer Research NetworkCredit: Pixabay/CC0 Public DomainAdding nab-paclitaxel to a standard treatment of gemcitabine plus cisplatin does not significantly extend median overall survival (OS) t

Updated on:December 17,2023

Technology that determines success of CAR T-cell immunotherapy could advance treatment of lymphoma

by Laurie Fickman,University of HoustonNavin Varadarajan, M.D. Anderson Professor of chemical and biomolecular engineering, studied the dynamic interactions between T cells and tumor cells to de

Updated on: December 26,2023

Technology that determines success of CAR T-cell immunotherapy could advance treatment of lymphoma

by Laurie Fickman,University of HoustonNavin Varadarajan, M.D. Anderson Professor of chemical and biomolecular engineering, studied the dynamic interactions between T cells and tumor cells to de

Updated on:December 26,2023

Genetic analysis of the most common type of bladder cancer yields guidance on treatment options

byUNC Lineberger Comprehensive Cancer CenterUC-GENOME study design and molecular subtyping shows enrichment of Stroma-rich primary tumors in metastatic datasets. Credit:Nature Communicatio

Updated on: December 21,2023

Genetic analysis of the most common type of bladder cancer yields guidance on treatment options

byUNC Lineberger Comprehensive Cancer CenterUC-GENOME study design and molecular subtyping shows enrichment of Stroma-rich primary tumors in metastatic datasets. Credit:Nature Communicatio

Updated on:December 21,2023

Protective mutation shown to impair esophagus tumor growth

byWellcome Trust Sanger InstituteDifferentiation and homeostasis in aged Notch1 mutant mouse tissue. a, YFPCreNotch1flox/floxmice were induced at high dose so mutant cells rapidly covered

Updated on: December 19,2023

Protective mutation shown to impair esophagus tumor growth

byWellcome Trust Sanger InstituteDifferentiation and homeostasis in aged Notch1 mutant mouse tissue. a, YFPCreNotch1flox/floxmice were induced at high dose so mutant cells rapidly covered

Updated on:December 19,2023

Personalised blood test could help predict which lung cancers might return

byGraeme Sneddon| News1 April 2022Patients who are at a higher risk of their lung cancer returning can be identified by a personalised blood test that is performed after treatment, accordi

Updated on: December 19,2023

Personalised blood test could help predict which lung cancers might return

byGraeme Sneddon| News1 April 2022Patients who are at a higher risk of their lung cancer returning can be identified by a personalised blood test that is performed after treatment, accordi

Updated on:December 19,2023

The structure of protein RAF1 revealed: A key step in the development of new drugs against lung cancer

byThe Spanish National Cancer Research CentreRAF1. Credit: CNIOOne of the main challenges in oncology is the development of drugs against KRAS oncogenes. These oncogenes—genes that cause cancer

Updated on: December 20,2023

The structure of protein RAF1 revealed: A key step in the development of new drugs against lung cancer

byThe Spanish National Cancer Research CentreRAF1. Credit: CNIOOne of the main challenges in oncology is the development of drugs against KRAS oncogenes. These oncogenes—genes that cause cancer

Updated on:December 20,2023

Three-country study provides insights into oral HPV incidence and risks in men

byH. Lee Moffitt Cancer Center & Research InstituteElectron micrograph of a negatively stained human papilloma virus (HPV) which occurs in human warts. Credit: public domainA new study has u

Updated on: November 15,2024

Three-country study provides insights into oral HPV incidence and risks in men

byH. Lee Moffitt Cancer Center & Research InstituteElectron micrograph of a negatively stained human papilloma virus (HPV) which occurs in human warts. Credit: public domainA new study has u

Updated on:November 15,2024

Change in breast density over time linked to cancer risk

by Tamara Bhandari,Washington University in St. LouisChange in Mammographic Density (MD) for the Case Breast in Case Patients and Control Participants Over Time. Credit:JAMA Oncology

Updated on: January 04,2024

Change in breast density over time linked to cancer risk

by Tamara Bhandari,Washington University in St. LouisChange in Mammographic Density (MD) for the Case Breast in Case Patients and Control Participants Over Time. Credit:JAMA Oncology

Updated on:January 04,2024

New technology in recent clinical study aims toward earlier detection of hepatocellular carcinoma

byUniversity of California, Los AngelesCredit: Pixabay/CC0 Public DomainPrimary liver cancer, the third-leading cause of cancer-related death worldwide, takes more than 30,000 lives in the Unite

Updated on: December 18,2023

New technology in recent clinical study aims toward earlier detection of hepatocellular carcinoma

byUniversity of California, Los AngelesCredit: Pixabay/CC0 Public DomainPrimary liver cancer, the third-leading cause of cancer-related death worldwide, takes more than 30,000 lives in the Unite

Updated on:December 18,2023

Tail spin: Study reveals new way to reduce friendly fire in cell therapy

by Bill Hathaway,Yale UniversityIn CAR-T therapy, T cells in blue find antigens (red) and kill cancer cells (purple). But often, antigens attach to other T cells leading other T cells to attack

Updated on: January 08,2024

Tail spin: Study reveals new way to reduce friendly fire in cell therapy

by Bill Hathaway,Yale UniversityIn CAR-T therapy, T cells in blue find antigens (red) and kill cancer cells (purple). But often, antigens attach to other T cells leading other T cells to attack

Updated on:January 08,2024

Universal genetic testing may improve risk stratification and treatment for rare and lethal cancer

Esophageal adenocarcinoma (EAC) is a highly lethal cancer, with a five-year survival rate of less than 20 percent. Although a precursor lesion to EAC, called Barrett's esophagus (BE), is present i

Updated on: November 19,2023

Universal genetic testing may improve risk stratification and treatment for rare and lethal cancer

Esophageal adenocarcinoma (EAC) is a highly lethal cancer, with a five-year survival rate of less than 20 percent. Although a precursor lesion to EAC, called Barrett's esophagus (BE), is present i

Updated on:November 19,2023