Scientists create an scRNA-seq atlas of the multiple myeloma immune microenvironment across disease stages

byVIB (the Flanders Institute for Biotechnology)The MM microenvironment is characterized by the presence of T cells with an exhausted phenotype. Credit:Journal of Hematology & Oncology

Updated on: December 02,2024

Scientists create an scRNA-seq atlas of the multiple myeloma immune microenvironment across disease stages

byVIB (the Flanders Institute for Biotechnology)The MM microenvironment is characterized by the presence of T cells with an exhausted phenotype. Credit:Journal of Hematology & Oncology

Updated on:December 02,2024

A treatment for metastasis? Using ferroptosis to attack migrating cancer cells

byFriedrich–Alexander University Erlangen–NurnbergZeb1 regulates the expression of enzymes crucial for adjusting the PUFA:MUFA ratio in phospholipids. Credit:Nature Cell Biology(2024

Updated on: July 17,2024

A treatment for metastasis? Using ferroptosis to attack migrating cancer cells

byFriedrich–Alexander University Erlangen–NurnbergZeb1 regulates the expression of enzymes crucial for adjusting the PUFA:MUFA ratio in phospholipids. Credit:Nature Cell Biology(2024

Updated on:July 17,2024

Study reveals mechanism involved in rare pediatric brain cancer and points to possible treatment

by André Julião,FAPESPThe study focused on supratentorial ependymoma with fusion of the genes C11orf95 and RELA [ST-RELA], a sub-group frequent in children. Credit: Taciani MagalhãesA study cond

Updated on: January 28,2024

Study reveals mechanism involved in rare pediatric brain cancer and points to possible treatment

by André Julião,FAPESPThe study focused on supratentorial ependymoma with fusion of the genes C11orf95 and RELA [ST-RELA], a sub-group frequent in children. Credit: Taciani MagalhãesA study cond

Updated on:January 28,2024

Patient step counts predict lung cancer treatment outcomes, study finds

byAmerican Society for Radiation OncologyCredit: CC0 Public DomainNumerous studies have shown that monitoring physical activity promotes better health—from reducing body mass index to watching f

Updated on: December 20,2023

Patient step counts predict lung cancer treatment outcomes, study finds

byAmerican Society for Radiation OncologyCredit: CC0 Public DomainNumerous studies have shown that monitoring physical activity promotes better health—from reducing body mass index to watching f

Updated on:December 20,2023

National prostate cancer trial currently testing therapy based on molecular discovery

byCleveland ClinicCredit:Journal of Clinical Investigation(2023). DOI: 10.1172/JCI163498A new prostate cancer therapy in clinical trials could treat patients resistant to treatment t

Updated on: December 23,2023

National prostate cancer trial currently testing therapy based on molecular discovery

byCleveland ClinicCredit:Journal of Clinical Investigation(2023). DOI: 10.1172/JCI163498A new prostate cancer therapy in clinical trials could treat patients resistant to treatment t

Updated on:December 23,2023

Peripheral blood haplo-SCT feasible for leukemia patients 70 years and older

by Elana GotkineFor patients with acute myeloid leukemia (AML)/myelodysplastic syndromes (MDS) aged 70 years and older, haploidentical stem cell transplantation (Haplo-SCT) using a nonmyeloablative co

Updated on: December 28,2023

Peripheral blood haplo-SCT feasible for leukemia patients 70 years and older

by Elana GotkineFor patients with acute myeloid leukemia (AML)/myelodysplastic syndromes (MDS) aged 70 years and older, haploidentical stem cell transplantation (Haplo-SCT) using a nonmyeloablative co

Updated on:December 28,2023

The obesity paradox in lung cancer diagnosis may differ by race

by Makhari Dysart,Thomas Jefferson UniversityCredit: Pixabay/CC0 Public DomainLung cancer is the leading cause of cancer death in the U.S., making up 25% of cancer deaths. With obesity rates sim

Updated on: December 22,2023

The obesity paradox in lung cancer diagnosis may differ by race

by Makhari Dysart,Thomas Jefferson UniversityCredit: Pixabay/CC0 Public DomainLung cancer is the leading cause of cancer death in the U.S., making up 25% of cancer deaths. With obesity rates sim

Updated on:December 22,2023

Mobile 'Man Van' spots prostate cancer more quickly and cheaply than via GPs

byInstitute of Cancer ResearchCredit: The Man Van and The Royal Marsden NHS Foundation TrustMobile testing "Man Van" can diagnose prostate cancer in at-risk groups earlier and more aff

Updated on: December 01,2024

Mobile 'Man Van' spots prostate cancer more quickly and cheaply than via GPs

byInstitute of Cancer ResearchCredit: The Man Van and The Royal Marsden NHS Foundation TrustMobile testing "Man Van" can diagnose prostate cancer in at-risk groups earlier and more aff

Updated on:December 01,2024

CAR-T Therapy Under Scrutiny: The Emerging Risk of Secondary Malignant Tumors

CAR-T therapy has long been an effective treatment for hematological cancers such as leukemia and lymphoma. However, some patients have developed secondary malignant tumors after undergoing CAR-T ......

Updated on: May 29,2024

CAR-T Therapy Under Scrutiny: The Emerging Risk of Secondary Malignant Tumors

CAR-T therapy has long been an effective treatment for hematological cancers such as leukemia and lymphoma. However, some patients have developed secondary malignant tumors after undergoing CAR-T ......

Updated on:May 29,2024

Novel form of immunotherapy could revolutionize cancer treatment

by Noelle Toumey Reetz,Georgia State UniversityFig. 1: Local RT eliminates late-stage MC38 tumors in Sirpα−/− mice but not WT mice. From: Intratumoral SIRPα-deficient macrophages activate tumor

Updated on: March 25,2024

Novel form of immunotherapy could revolutionize cancer treatment

by Noelle Toumey Reetz,Georgia State UniversityFig. 1: Local RT eliminates late-stage MC38 tumors in Sirpα−/− mice but not WT mice. From: Intratumoral SIRPα-deficient macrophages activate tumor

Updated on:March 25,2024

Patients with cancer, suppressed immune system at high risk for severe COVID if treated with systemic drug therapies

byDana-Farber Cancer InstituteCredit: Unsplash/CC0 Public DomainPatients with cancer and a weakened immune system who are treated with immunotherapies tend to fare far worse from COVID-19 than t

Updated on: December 18,2023

Patients with cancer, suppressed immune system at high risk for severe COVID if treated with systemic drug therapies

byDana-Farber Cancer InstituteCredit: Unsplash/CC0 Public DomainPatients with cancer and a weakened immune system who are treated with immunotherapies tend to fare far worse from COVID-19 than t

Updated on:December 18,2023

Immune cells trained to hunt tumors after scientists plant synthetic 'flags' on cancer

Updated on: June 15,2025

Immune cells trained to hunt tumors after scientists plant synthetic 'flags' on cancer

Updated on:June 15,2025