p53 mutations in 10,000 cancer patients shed new light on gene's function

by Molly Chiu,Baylor College of MedicineKiller T cells surround a cancer cell. Credit: NIHOne of the most extensively studied genes in cancer, TP53 is well known for its role as a tumor suppress

Updated on: March 14,2024

p53 mutations in 10,000 cancer patients shed new light on gene's function

by Molly Chiu,Baylor College of MedicineKiller T cells surround a cancer cell. Credit: NIHOne of the most extensively studied genes in cancer, TP53 is well known for its role as a tumor suppress

Updated on:March 14,2024

Study reveals mechanism involved in rare pediatric brain cancer and points to possible treatment

by André Julião,FAPESPThe study focused on supratentorial ependymoma with fusion of the genes C11orf95 and RELA [ST-RELA], a sub-group frequent in children. Credit: Taciani MagalhãesA study cond

Updated on: January 28,2024

Study reveals mechanism involved in rare pediatric brain cancer and points to possible treatment

by André Julião,FAPESPThe study focused on supratentorial ependymoma with fusion of the genes C11orf95 and RELA [ST-RELA], a sub-group frequent in children. Credit: Taciani MagalhãesA study cond

Updated on:January 28,2024

Patients with HPV-positive oropharynx cancer should receive chemoradiation

byEuropean Society for Medical OncologyProf Hisham Mehanna, Chair, Head and Neck Surgery, Institute of Cancer and Genomic Sciences, University of Birmingham, UK, study author. Credit: © European

Updated on: December 18,2023

Patients with HPV-positive oropharynx cancer should receive chemoradiation

byEuropean Society for Medical OncologyProf Hisham Mehanna, Chair, Head and Neck Surgery, Institute of Cancer and Genomic Sciences, University of Birmingham, UK, study author. Credit: © European

Updated on:December 18,2023

Targeted therapy extends survival in cancers of unknown primary

by Julia Bird, Universitätsklinikum HeidelbergProgression-free survival in the intention-to-treat population, category 1 patients. Credit:The Lancet(2024). DOI: 10.1016/S0140-6736(24)00814

Updated on: August 27,2024

Targeted therapy extends survival in cancers of unknown primary

by Julia Bird, Universitätsklinikum HeidelbergProgression-free survival in the intention-to-treat population, category 1 patients. Credit:The Lancet(2024). DOI: 10.1016/S0140-6736(24)00814

Updated on:August 27,2024

Modular chimeric cytokine receptors improve CAR T-cell therapy for solid tumors

bySt. Jude Children's Research HospitalTwo leucine zipper motifs endow ZipRs with constitutive signal transduction.a, Schematic of IL-2 receptor-based Zip2Rs with phosphorylated (p) JA

Updated on: January 26,2024

Modular chimeric cytokine receptors improve CAR T-cell therapy for solid tumors

bySt. Jude Children's Research HospitalTwo leucine zipper motifs endow ZipRs with constitutive signal transduction.a, Schematic of IL-2 receptor-based Zip2Rs with phosphorylated (p) JA

Updated on:January 26,2024

New drug combinations could improve therapies for breast cancer, other aggressive cancers

by Angela Yeager,Oregon Health & Science UniversityQuantification of CD8+T cells by multispectral flow cytometry in an ex vivo co-culture assay. Credit:Cell Reports Medicine&nbsp

Updated on: September 10,2024

New drug combinations could improve therapies for breast cancer, other aggressive cancers

by Angela Yeager,Oregon Health & Science UniversityQuantification of CD8+T cells by multispectral flow cytometry in an ex vivo co-culture assay. Credit:Cell Reports Medicine&nbsp

Updated on:September 10,2024

Defensive beliefs likely keep people from taking at-home stool tests that screen for colorectal cancer

byWileyCancer—Histopathologic image of colonic carcinoid. Credit: Wikipedia/CC BY-SA 3.0Colorectal cancer is one of the most treatable cancers, especially if it is detected early; however, many

Updated on: December 22,2023

Defensive beliefs likely keep people from taking at-home stool tests that screen for colorectal cancer

byWileyCancer—Histopathologic image of colonic carcinoid. Credit: Wikipedia/CC BY-SA 3.0Colorectal cancer is one of the most treatable cancers, especially if it is detected early; however, many

Updated on:December 22,2023

Most Americans don't know about lung cancer screening, survey shows

by Ernie MundellCredit: Anna Tarazevich from PexelsPeople who've had a history of smoking can get alung cancerspotted early—when it's most treatable—through annual CT screening.Unf

Updated on: August 27,2024

Most Americans don't know about lung cancer screening, survey shows

by Ernie MundellCredit: Anna Tarazevich from PexelsPeople who've had a history of smoking can get alung cancerspotted early—when it's most treatable—through annual CT screening.Unf

Updated on:August 27,2024

Biomarker blood test confirms remission in patients with HPV+ oral cancer

byAmerican Society for Radiation OncologyA highly sensitive blood test that detects minute traces of cancer-specific DNA has been shown to accurately determine whether patients with HPV-related

Updated on: December 18,2023

Biomarker blood test confirms remission in patients with HPV+ oral cancer

byAmerican Society for Radiation OncologyA highly sensitive blood test that detects minute traces of cancer-specific DNA has been shown to accurately determine whether patients with HPV-related

Updated on:December 18,2023

Minimizing immunotherapy's potentially harmful side effects

byUniversity of Miami Leonard M. Miller School of MedicineCredit: Pixabay/CC0 Public DomainRecent advances in treating multiple myeloma, the second most common blood cancer, and other blood mali

Updated on: January 25,2024

Minimizing immunotherapy's potentially harmful side effects

byUniversity of Miami Leonard M. Miller School of MedicineCredit: Pixabay/CC0 Public DomainRecent advances in treating multiple myeloma, the second most common blood cancer, and other blood mali

Updated on:January 25,2024

Boosting the cancer-destroying ability of killer T-cells

by Julia Short,Cardiff UniversityCredit: CC0 Public DomainMore types of cancer could potentially be destroyed by patients' own immune cells, thanks to new research by Cardiff University.The

Updated on: April 18,2024

Boosting the cancer-destroying ability of killer T-cells

by Julia Short,Cardiff UniversityCredit: CC0 Public DomainMore types of cancer could potentially be destroyed by patients' own immune cells, thanks to new research by Cardiff University.The

Updated on:April 18,2024

New method for early detection of multi-cancers based on human metabolism

bySwedish Research CouncilValidation of the pruned combined free GAGome MCED score. (A) Validation study subject flow (see also SI Appendix, Fig. S17). (B) Pruned combined free GAGome MCED score

Updated on: December 25,2023

New method for early detection of multi-cancers based on human metabolism

bySwedish Research CouncilValidation of the pruned combined free GAGome MCED score. (A) Validation study subject flow (see also SI Appendix, Fig. S17). (B) Pruned combined free GAGome MCED score

Updated on:December 25,2023