Researchers develop new open-source method to improve decoding of single-cell data

by Ian Demsky,Memorial Sloan Kettering Cancer CenterSpectra uses gene sets and cell types to guide gene program discovery from scRNA-seq data.a, As input, Spectra receives a gene expressio

Updated on: June 11,2024

Researchers develop new open-source method to improve decoding of single-cell data

by Ian Demsky,Memorial Sloan Kettering Cancer CenterSpectra uses gene sets and cell types to guide gene program discovery from scRNA-seq data.a, As input, Spectra receives a gene expressio

Updated on:June 11,2024

Extreme phenotype approach identifies rare ATR variants as potential male breast cancer susceptibility alleles

by Impact Journals LLCImpact of splicing variants. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.28358In oncogenetics, some patients could be considered as "extreme phenotypes,&qu

Updated on: December 25,2023

Extreme phenotype approach identifies rare ATR variants as potential male breast cancer susceptibility alleles

by Impact Journals LLCImpact of splicing variants. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.28358In oncogenetics, some patients could be considered as "extreme phenotypes,&qu

Updated on:December 25,2023

What is the breast cancer risk calculator recommended by Olivia Munn?

by Carla K. JohnsonOlivia Munn arrives at the Governors Awards on Tuesday, Jan. 9, 2024, at the Dolby Ballroom in Los Angeles. When Munn revealed in March 2024 that she was diagnosed with breast cance

Updated on: March 20,2024

What is the breast cancer risk calculator recommended by Olivia Munn?

by Carla K. JohnsonOlivia Munn arrives at the Governors Awards on Tuesday, Jan. 9, 2024, at the Dolby Ballroom in Los Angeles. When Munn revealed in March 2024 that she was diagnosed with breast cance

Updated on:March 20,2024

Study reveals gene 'switched off' in early stages of pancreatic cancer allows rapid tumor growth and spread

byNottingham Trent UniversityHNF4A is methylated and suppressed in pancreatic cancer. Credit:Gastro Hep Advances(2024). DOI: 10.1016/j.gastha.2024.04.005Scientists at Nottingham Tren

Updated on: July 17,2024

Study reveals gene 'switched off' in early stages of pancreatic cancer allows rapid tumor growth and spread

byNottingham Trent UniversityHNF4A is methylated and suppressed in pancreatic cancer. Credit:Gastro Hep Advances(2024). DOI: 10.1016/j.gastha.2024.04.005Scientists at Nottingham Tren

Updated on:July 17,2024

Researchers discover the role of RNF114B, a key gene in the progression and treatment of lung adenocarcinoma

byUniversitat Pompeu Fabra - BarcelonaA mouse fibroblast with altered RNF144B expression divides without correctly grouping chromosomes (stained blue), resulting in aberrant cells. Credit: UPFRe

Updated on: July 09,2024

Researchers discover the role of RNF114B, a key gene in the progression and treatment of lung adenocarcinoma

byUniversitat Pompeu Fabra - BarcelonaA mouse fibroblast with altered RNF144B expression divides without correctly grouping chromosomes (stained blue), resulting in aberrant cells. Credit: UPFRe

Updated on:July 09,2024

New drug could unlock benefits of immunotherapy for more patients

FEBRUARY 27, 2024byInstitute of Cancer ResearchAntitumor responses. Credit:Journal of Clinical Investigation(2023). DOI: 10.1172/JCI175369A new drug could offer a powerful way to sen

Updated on: March 25,2024

New drug could unlock benefits of immunotherapy for more patients

FEBRUARY 27, 2024byInstitute of Cancer ResearchAntitumor responses. Credit:Journal of Clinical Investigation(2023). DOI: 10.1172/JCI175369A new drug could offer a powerful way to sen

Updated on:March 25,2024

Gene interactions classify bowel tumors for personalized medicine

byeLifeFlowchart of the interaction-perturbation-based program. As an example, the background network consists of six genes and five interactions. There were three normal samples (yellow) and th

Updated on: December 25,2023

Gene interactions classify bowel tumors for personalized medicine

byeLifeFlowchart of the interaction-perturbation-based program. As an example, the background network consists of six genes and five interactions. There were three normal samples (yellow) and th

Updated on:December 25,2023

Antibody-based therapy eliminates circulating tumor cells in mouse models of breast and pancreatic cancer

by Katie Marquedant,Massachusetts General Hospital(A) Schema for the mouse models of neoadjuvant placebo or 23C6 treatment. (B) Tumor volume measurements of 4T1 orthotopic mammary gland tumors i

Updated on: December 25,2023

Antibody-based therapy eliminates circulating tumor cells in mouse models of breast and pancreatic cancer

by Katie Marquedant,Massachusetts General Hospital(A) Schema for the mouse models of neoadjuvant placebo or 23C6 treatment. (B) Tumor volume measurements of 4T1 orthotopic mammary gland tumors i

Updated on:December 25,2023

Black men found to have greater microvascular dysfunction than white men after prostate cancer diagnosis

byAmerican Physiological SocietyCredit: Pixabay/CC0 Public DomainMicrovascular function is lower is Black men following a recent diagnosis of prostate cancer, compared to white men, according to

Updated on: April 30,2024

Black men found to have greater microvascular dysfunction than white men after prostate cancer diagnosis

byAmerican Physiological SocietyCredit: Pixabay/CC0 Public DomainMicrovascular function is lower is Black men following a recent diagnosis of prostate cancer, compared to white men, according to

Updated on:April 30,2024

How sound waves trigger immune responses to cancer in mice

byUniversity of MichiganHistotripsy ablation is followed by infiltration of innate and adaptive immune cell populations. Mice bearing bilateral B16F10 tumors were treated with unilateral sham (c

Updated on: January 04,2024

How sound waves trigger immune responses to cancer in mice

byUniversity of MichiganHistotripsy ablation is followed by infiltration of innate and adaptive immune cell populations. Mice bearing bilateral B16F10 tumors were treated with unilateral sham (c

Updated on:January 04,2024

Liver cancer 'signature' in gut holds clues to cancer risk

by Caroline Tang,University of New South WalesCredit: Thirdman from PexelsPeople with non-alcohol-related liver cancer have a unique gut microbiome profile which could help predict disease risk,

Updated on: June 20,2024

Liver cancer 'signature' in gut holds clues to cancer risk

by Caroline Tang,University of New South WalesCredit: Thirdman from PexelsPeople with non-alcohol-related liver cancer have a unique gut microbiome profile which could help predict disease risk,

Updated on:June 20,2024

Updates: MET targeted therapy for EXON 14 mutations in lung cancer

by Impact Journals LLCCredit: Pixabay/CC0 Public DomainAnew editorial papertitled "Latest updates on MET targeted therapy for EXON 14 mutations in lung cancer" has been published

Updated on: March 21,2024

Updates: MET targeted therapy for EXON 14 mutations in lung cancer

by Impact Journals LLCCredit: Pixabay/CC0 Public DomainAnew editorial papertitled "Latest updates on MET targeted therapy for EXON 14 mutations in lung cancer" has been published

Updated on:March 21,2024