Extracellular cell matrix stiffness may induce drug resistance of breast cancer cells

by Shanghai Jiao Tong University Journal CenterCredit:Mechanobiology in Medicine(2023). DOI: 10.1016/j.mbm.2023.100023A new study, led by Prof. Liu from the department of pharmacy, Univers

Updated on: April 30,2024

Extracellular cell matrix stiffness may induce drug resistance of breast cancer cells

by Shanghai Jiao Tong University Journal CenterCredit:Mechanobiology in Medicine(2023). DOI: 10.1016/j.mbm.2023.100023A new study, led by Prof. Liu from the department of pharmacy, Univers

Updated on:April 30,2024

Early genome catastrophes can cause non-smoking lung cancer

by The Korea Advanced Institute of Science and Technology (KAIST)Smoking-unrelated oncogenesis of lung cancers by gene fusions. Credit: The Korea Advanced Institute of Science and Technology (KAI

Updated on: April 20,2024

Early genome catastrophes can cause non-smoking lung cancer

by The Korea Advanced Institute of Science and Technology (KAIST)Smoking-unrelated oncogenesis of lung cancers by gene fusions. Credit: The Korea Advanced Institute of Science and Technology (KAI

Updated on:April 20,2024

Tumor resistance is promoted by anti-cancer protein

by Champalimaud Centre for the UnknownCredit: CC0 Public DomainLack of oxygen, or hypoxia, is a biological stressor that occurs under various conditions such as wound healing and stroke. To rescue the

Updated on: April 09,2024

Tumor resistance is promoted by anti-cancer protein

by Champalimaud Centre for the UnknownCredit: CC0 Public DomainLack of oxygen, or hypoxia, is a biological stressor that occurs under various conditions such as wound healing and stroke. To rescue the

Updated on:April 09,2024

Novel anti-cancer nanomedicine for efficient chemotherapy

by University of HelsinkiThe new exosome-based nanomedicines enhanced tumor accumulation, extravasation from blood vessels and penetration into deep tumor parenchyma after intravenous administrat

Updated on: May 09,2024

Novel anti-cancer nanomedicine for efficient chemotherapy

by University of HelsinkiThe new exosome-based nanomedicines enhanced tumor accumulation, extravasation from blood vessels and penetration into deep tumor parenchyma after intravenous administrat

Updated on:May 09,2024

Researchers link overexpression of MDMX protein to metastasis of 3X negative breast cancer

by The City University of New YorkThe MDMX and MDM2 proteins promote metastasis in triple-negative breast cancer, while the MDM2 protein promotes tumor growth in estrogen receptor a-positive brea

Updated on: June 15,2024

Researchers link overexpression of MDMX protein to metastasis of 3X negative breast cancer

by The City University of New YorkThe MDMX and MDM2 proteins promote metastasis in triple-negative breast cancer, while the MDM2 protein promotes tumor growth in estrogen receptor a-positive brea

Updated on:June 15,2024

How communication in the tumor microenvironment influences tumor development

by Goethe UniversityTissue section of a lung tumor showing different cells in the tumor microenvironment: macrophages (red), collagen-producing macrophages or fibrocytes (yellow), fibroblasts (green).

Updated on: January 23,2024

How communication in the tumor microenvironment influences tumor development

by Goethe UniversityTissue section of a lung tumor showing different cells in the tumor microenvironment: macrophages (red), collagen-producing macrophages or fibrocytes (yellow), fibroblasts (green).

Updated on:January 23,2024

Elegant antibody nanoparticles override immunological tolerance of tumors

by Chinese Academy of SciencesSchematic illustration of the engineered antibody nanoparticle for robust cancer immunotherapy. Credit: WANG DanggeImmune checkpoint blockade (ICB) therapy using the

Updated on: May 09,2024

Elegant antibody nanoparticles override immunological tolerance of tumors

by Chinese Academy of SciencesSchematic illustration of the engineered antibody nanoparticle for robust cancer immunotherapy. Credit: WANG DanggeImmune checkpoint blockade (ICB) therapy using the

Updated on:May 09,2024

Genomic deletions explain why some types of melanoma resist targeted therapies

byCenter for Genomic RegulationCredit: CC0 Public DomainMelanoma is the deadliest form of skin cancer. With global incidence rates rising, new, more effective treatments are necessary to allevia

Updated on: April 28,2024

Genomic deletions explain why some types of melanoma resist targeted therapies

byCenter for Genomic RegulationCredit: CC0 Public DomainMelanoma is the deadliest form of skin cancer. With global incidence rates rising, new, more effective treatments are necessary to allevia

Updated on:April 28,2024

Some proteogenomic signatures linked to prostate cancer progression in patients with African and European ancestries

byAmerican Association for Cancer ResearchCredit: Unsplash/CC0 Public DomainCertain proteogenomic signatures in the prostate cancers of men of African and European ancestries were associated wit

Updated on: April 28,2024

Some proteogenomic signatures linked to prostate cancer progression in patients with African and European ancestries

byAmerican Association for Cancer ResearchCredit: Unsplash/CC0 Public DomainCertain proteogenomic signatures in the prostate cancers of men of African and European ancestries were associated wit

Updated on:April 28,2024

Study links mutations in notch gene to role in B cell cancers

by Perelman School of Medicine at the University of PennsylvaniaPeripheral blood with chronic lymphocytic leukemia cells. Credit: Jon Aster, Harvard Medical SchoolNotch is one of the most frequen

Updated on: July 02,2024

Study links mutations in notch gene to role in B cell cancers

by Perelman School of Medicine at the University of PennsylvaniaPeripheral blood with chronic lymphocytic leukemia cells. Credit: Jon Aster, Harvard Medical SchoolNotch is one of the most frequen

Updated on:July 02,2024

Study shows novel agent can overcome immune dysfunction in cancer

by Roswell Park Comprehensive Cancer CenterVSSP restores myeloid cell frequencies following leukopenia. C57BL/6 mice were injected with CY (200 mg/kg body weight, i.p.) and with two consecutive daily

Updated on: January 22,2024

Study shows novel agent can overcome immune dysfunction in cancer

by Roswell Park Comprehensive Cancer CenterVSSP restores myeloid cell frequencies following leukopenia. C57BL/6 mice were injected with CY (200 mg/kg body weight, i.p.) and with two consecutive daily

Updated on:January 22,2024

Second primary malignancies represent small proportion of adverse events after CAR T-cell therapy

by Elana GotkineSecond primary malignancies (SPMs) represent a small proportion of adverse events (AEs) reported by patients receiving chimeric antigen receptor T-cell (CAR T-cell) therapy, according

Updated on: March 30,2024

Second primary malignancies represent small proportion of adverse events after CAR T-cell therapy

by Elana GotkineSecond primary malignancies (SPMs) represent a small proportion of adverse events (AEs) reported by patients receiving chimeric antigen receptor T-cell (CAR T-cell) therapy, according

Updated on:March 30,2024