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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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Research team creates more effective lymphatic cancer therapy

Research team creates more effective lymphatic cancer therapy

byTohoku UniversityThe ex vivo bioluminescence intensity of the metastatic LN was lowest in the Single M-TBI + LDDS group, followed by the Single M-TBI group and the LDDS group, and all these gr

Research team creates more effective lymphatic cancer therapy

byTohoku UniversityThe ex vivo bioluminescence intensity of the metastatic LN was lowest in the Single M-TBI + LDDS group, followed by the Single M-TBI group and the LDDS group, and all these gr
Taxane-induced peripheral neuropathy in breast cancer: Frequent, clinically significant, and worse with paclitaxel

Taxane-induced peripheral neuropathy in breast cancer: Frequent, clinically significant, and worse with paclitaxel

by SWOG Cancer Research NetworkCredit: Unsplash/CC0 Public DomainChemotherapy-induced peripheral neuropathy (CIPN)—nerve pain, tingling, or numbness in the hands or feet—is a common side effect of cer

Taxane-induced peripheral neuropathy in breast cancer: Frequent, clinically significant, and worse with paclitaxel

by SWOG Cancer Research NetworkCredit: Unsplash/CC0 Public DomainChemotherapy-induced peripheral neuropathy (CIPN)—nerve pain, tingling, or numbness in the hands or feet—is a common side effect of cer
Selective protection of normal cells from chemotherapy, while killing drug-resistant cancer cells

Selective protection of normal cells from chemotherapy, while killing drug-resistant cancer cells

by Impact JournalsCaspase inhibitors (CI) selectively protect normal cells from chemotherapy-induced apoptosis, without protection multidrug-resistant cancer cells. Flavopiridol (shown in red, as a cy

Selective protection of normal cells from chemotherapy, while killing drug-resistant cancer cells

by Impact JournalsCaspase inhibitors (CI) selectively protect normal cells from chemotherapy-induced apoptosis, without protection multidrug-resistant cancer cells. Flavopiridol (shown in red, as a cy
New therapeutic opportunity for the treatment of resistant malignant melanoma

New therapeutic opportunity for the treatment of resistant malignant melanoma

by University de LiegeMelanoma in skin biopsy with H&E stain—this case may represent superficial spreading melanoma. Credit: Wikipedia/CC BY-SA 3.0A team of researchers led by Dr. Pierre Clos

New therapeutic opportunity for the treatment of resistant malignant melanoma

by University de LiegeMelanoma in skin biopsy with H&E stain—this case may represent superficial spreading melanoma. Credit: Wikipedia/CC BY-SA 3.0A team of researchers led by Dr. Pierre Clos
Better together: Spatial arrangement of three immune cells is key to attacking tumors, study finds

Better together: Spatial arrangement of three immune cells is key to attacking tumors, study finds

by Matthew Tontonoz,Memorial Sloan Kettering Cancer CenterGraphical abstract. Credit:Cancer Cell(2024). DOI: 10.1016/j.ccell.2024.05.025There's a frustrating fact about today&#39

Better together: Spatial arrangement of three immune cells is key to attacking tumors, study finds

by Matthew Tontonoz,Memorial Sloan Kettering Cancer CenterGraphical abstract. Credit:Cancer Cell(2024). DOI: 10.1016/j.ccell.2024.05.025There's a frustrating fact about today&#39
Fighting aggressive blood cancer ages and exhausts immune cells, study shows

Fighting aggressive blood cancer ages and exhausts immune cells, study shows

byNottingham Trent UniversityGraphical abstract. Credit:Journal of Clinical Investigation(2022). DOI: 10.1172/JCI159579Scientists at Nottingham Trent University and John Hopkins Kimm

Fighting aggressive blood cancer ages and exhausts immune cells, study shows

byNottingham Trent UniversityGraphical abstract. Credit:Journal of Clinical Investigation(2022). DOI: 10.1172/JCI159579Scientists at Nottingham Trent University and John Hopkins Kimm
Scientists unravel mystery of drug response in small cell lung cancer

Scientists unravel mystery of drug response in small cell lung cancer

by University of CologneTumor samples and clinical history of 65 patients with SCLC. a, Tumor sites sampled from 65 patients with SCLC. Frequently sampled sites are highlighted in bold. Tumors we

Scientists unravel mystery of drug response in small cell lung cancer

by University of CologneTumor samples and clinical history of 65 patients with SCLC. a, Tumor sites sampled from 65 patients with SCLC. Frequently sampled sites are highlighted in bold. Tumors we
Exploring ways to overcome cisplatin resistance and alleviate pain in cancer treatment

Exploring ways to overcome cisplatin resistance and alleviate pain in cancer treatment

by Korea University College of MedicineThe study reveals that the transcription factor NANOG activates the transient receptor potential vanilloid 1 (TRPV1)—causing neuropathic pain. TRPV1 further stim

Exploring ways to overcome cisplatin resistance and alleviate pain in cancer treatment

by Korea University College of MedicineThe study reveals that the transcription factor NANOG activates the transient receptor potential vanilloid 1 (TRPV1)—causing neuropathic pain. TRPV1 further stim
How oxygen deprivation causes cancer cells to spread

How oxygen deprivation causes cancer cells to spread

byLeiden UniversityCredit: Pixabay/CC0 Public DomainIn breast cancer, metastasis rather than the primary tumor is the cause of death. A lack of oxygen in the tumor cells promotes this metastasis

How oxygen deprivation causes cancer cells to spread

byLeiden UniversityCredit: Pixabay/CC0 Public DomainIn breast cancer, metastasis rather than the primary tumor is the cause of death. A lack of oxygen in the tumor cells promotes this metastasis
Study gauges specific site stomach cancer risks among ethnic groups

Study gauges specific site stomach cancer risks among ethnic groups

by Vanderbilt University Medical CenterCredit: CC0 Public DomainNon-white Americans, especially Asian Americans, are at disproportionately higher risk for gastric cancer compared to non-Hispanic

Study gauges specific site stomach cancer risks among ethnic groups

by Vanderbilt University Medical CenterCredit: CC0 Public DomainNon-white Americans, especially Asian Americans, are at disproportionately higher risk for gastric cancer compared to non-Hispanic
Extending chemo slashes risk of aggressive childhood leukemia coming back

Extending chemo slashes risk of aggressive childhood leukemia coming back

by Princess Máxima Center for Pediatric OncologyCredit: CC0 Public DomainMany children with acute lymphoblastic leukemia (ALL) have a good outcome of their disease. After two years of chemotherapy tre

Extending chemo slashes risk of aggressive childhood leukemia coming back

by Princess Máxima Center for Pediatric OncologyCredit: CC0 Public DomainMany children with acute lymphoblastic leukemia (ALL) have a good outcome of their disease. After two years of chemotherapy tre
Researchers reveal key mechanism of natural killer cell dysfunction

Researchers reveal key mechanism of natural killer cell dysfunction

by Liu Jia,Chinese Academy of SciencesIntratumoral NK cells lack abundant membrane protrusions. Credit:Nature Immunology(2023). DOI: 10.1038/s41590-023-01462-9A team has revealed the

Researchers reveal key mechanism of natural killer cell dysfunction

by Liu Jia,Chinese Academy of SciencesIntratumoral NK cells lack abundant membrane protrusions. Credit:Nature Immunology(2023). DOI: 10.1038/s41590-023-01462-9A team has revealed the