Trial finds that adagrasib demonstrates durable clinical activity in patients with KRAS-G12C mutations

by International Association for the Study of Lung CancerCredit: Pixabay/CC0 Public DomainThe oral, selective KRAS G12C inhibitor KRAS-G12C inhibitor adagrasib demonstrated durable clinical activity,

Updated on: January 04,2024

Trial finds that adagrasib demonstrates durable clinical activity in patients with KRAS-G12C mutations

by International Association for the Study of Lung CancerCredit: Pixabay/CC0 Public DomainThe oral, selective KRAS G12C inhibitor KRAS-G12C inhibitor adagrasib demonstrated durable clinical activity,

Updated on:January 04,2024

A cell surface marker for identifying tumor-initiating cells in pancreatic cancer

by Kumamoto UniversityROR1 is a cell surface receptor that promotes hyperproliferation, metastasis, and relapse in PDAC when highly expressed. Suppressing ROR1 reduces PDAC growth. Credit: Masaya

Updated on: February 19,2024

A cell surface marker for identifying tumor-initiating cells in pancreatic cancer

by Kumamoto UniversityROR1 is a cell surface receptor that promotes hyperproliferation, metastasis, and relapse in PDAC when highly expressed. Suppressing ROR1 reduces PDAC growth. Credit: Masaya

Updated on:February 19,2024

Avoid unnecessary removal of lymph nodes in breast cancer, recommends new study

by Universitätsklinikum HeidelbergRadiation planning CT after axillary lymph node dissection. The arrow shows the clips at the upper border of axillary dissection. No surgical changes are noted behind

Updated on: January 29,2024

Avoid unnecessary removal of lymph nodes in breast cancer, recommends new study

by Universitätsklinikum HeidelbergRadiation planning CT after axillary lymph node dissection. The arrow shows the clips at the upper border of axillary dissection. No surgical changes are noted behind

Updated on:January 29,2024

Study suggests lung cancer does not decrease in line with reduced smoking

byUmea UniversityIncidence rates for lung cancer according to age, sex and time (cases/100,000 person-years). Notice the different scales on the vertical axes (incidence rates). Credit:Eur

Updated on: April 06,2024

Study suggests lung cancer does not decrease in line with reduced smoking

byUmea UniversityIncidence rates for lung cancer according to age, sex and time (cases/100,000 person-years). Notice the different scales on the vertical axes (incidence rates). Credit:Eur

Updated on:April 06,2024

One lung cancer drug receives NHS England approval, while another is rejected

by Cancer Research UKCredit: CC0 Public DomainA targeted drug has been accepted for routine use on the NHS in England for some adults with untreated, advanced lung cancer. But another precision d

Updated on: May 20,2024

One lung cancer drug receives NHS England approval, while another is rejected

by Cancer Research UKCredit: CC0 Public DomainA targeted drug has been accepted for routine use on the NHS in England for some adults with untreated, advanced lung cancer. But another precision d

Updated on:May 20,2024

Front-line osimertinib improves overall survival in EGFR-mutation positive NSCLC

by European Society for Medical OncologyCredit: © European Society for Medical OncologyFirst-line osimertinib significantly lengthens overall survival compared to older generation EGFR-TKIs in pa

Updated on: May 23,2024

Front-line osimertinib improves overall survival in EGFR-mutation positive NSCLC

by European Society for Medical OncologyCredit: © European Society for Medical OncologyFirst-line osimertinib significantly lengthens overall survival compared to older generation EGFR-TKIs in pa

Updated on:May 23,2024

New CAR T-cell immunotherapy shows promising results for treating blood cancer patients

byKing's College LondonUCART19 cellular kinetics and correlation with clinical response. A, Graphical representation of UCART19 kinetic profile in PB of patients with B-ALL in the CALM study

Updated on: January 11,2024

New CAR T-cell immunotherapy shows promising results for treating blood cancer patients

byKing's College LondonUCART19 cellular kinetics and correlation with clinical response. A, Graphical representation of UCART19 kinetic profile in PB of patients with B-ALL in the CALM study

Updated on:January 11,2024

Liquid biopsy as effective as tissue biopsy for non-small cell lung cancer: study

by University of Texas M. D. Anderson Cancer CenterVassiliki Papadimitrakopoulou, M.D. Credit: MD Anderson Cancer CenterA multi-center study led by researchers at The University of Texas MD Ander

Updated on: May 23,2024

Liquid biopsy as effective as tissue biopsy for non-small cell lung cancer: study

by University of Texas M. D. Anderson Cancer CenterVassiliki Papadimitrakopoulou, M.D. Credit: MD Anderson Cancer CenterA multi-center study led by researchers at The University of Texas MD Ander

Updated on:May 23,2024

Immune landscape and response to oncolytic virus-based immunotherapy

by Frontiers JournalsCredit:Frontiers of Medicine(2024). DOI: 10.1007/s11684-023-1048-0Oncolytic virus (OV)-based immunotherapy has emerged as a promising strategy for cancer treatment, of

Updated on: August 28,2024

Immune landscape and response to oncolytic virus-based immunotherapy

by Frontiers JournalsCredit:Frontiers of Medicine(2024). DOI: 10.1007/s11684-023-1048-0Oncolytic virus (OV)-based immunotherapy has emerged as a promising strategy for cancer treatment, of

Updated on:August 28,2024

Study confirms curable state between single and widespread cancers

by University of Chicago Medical CenterRalph Weichselbaum, M.D., the Daniel K. Ludwig Distinguished Service Professor, chair of radiation and cellular oncology at UChicago and director of the Lud

Updated on: March 01,2024

Study confirms curable state between single and widespread cancers

by University of Chicago Medical CenterRalph Weichselbaum, M.D., the Daniel K. Ludwig Distinguished Service Professor, chair of radiation and cellular oncology at UChicago and director of the Lud

Updated on:March 01,2024

Discovery adds to evidence that some children are predisposed to develop leukemia

by St. Jude Children's Research HospitalCharles Mullighan, MBBS, M.D., Michelle Churchman Ph.D., Max Qian PhD, Jun Yang Ph.D. Credit: St. Jude Children's Research Hospital / Seth DixonSt.

Updated on: April 14,2024

Discovery adds to evidence that some children are predisposed to develop leukemia

by St. Jude Children's Research HospitalCharles Mullighan, MBBS, M.D., Michelle Churchman Ph.D., Max Qian PhD, Jun Yang Ph.D. Credit: St. Jude Children's Research Hospital / Seth DixonSt.

Updated on:April 14,2024

Researchers peer inside cells to spy on cancer's on-off switch

by Lisa Marshall,University of Colorado at BoulderCredit: University of Colorado at BoulderForty years after researchers first discovered it in fruit flies, a once-obscure cluster of proteins ca

Updated on: June 06,2024

Researchers peer inside cells to spy on cancer's on-off switch

by Lisa Marshall,University of Colorado at BoulderCredit: University of Colorado at BoulderForty years after researchers first discovered it in fruit flies, a once-obscure cluster of proteins ca

Updated on:June 06,2024