Genomic deletions explain why some types of melanoma resist targeted therapies

byCenter for Genomic RegulationCredit: CC0 Public DomainMelanoma is the deadliest form of skin cancer. With global incidence rates rising, new, more effective treatments are necessary to allevia

Updated on: April 28,2024

Genomic deletions explain why some types of melanoma resist targeted therapies

byCenter for Genomic RegulationCredit: CC0 Public DomainMelanoma is the deadliest form of skin cancer. With global incidence rates rising, new, more effective treatments are necessary to allevia

Updated on:April 28,2024

Unraveling role of tumor suppressor in gene expression and ovarian tumorigenesis

by The Wistar InstituteCredit: CC0 Public DomainThe tumor suppressor protein ARID1A controls global transcription in ovarian epithelial cells, according to new research conducted at The Wistar In

Updated on: April 07,2024

Unraveling role of tumor suppressor in gene expression and ovarian tumorigenesis

by The Wistar InstituteCredit: CC0 Public DomainThe tumor suppressor protein ARID1A controls global transcription in ovarian epithelial cells, according to new research conducted at The Wistar In

Updated on:April 07,2024

Mechanism of a breast cancer drug points to a possible new therapy

by Sarah Avery,Duke UniversityThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Image created in 2014 by Tom

Updated on: May 20,2024

Mechanism of a breast cancer drug points to a possible new therapy

by Sarah Avery,Duke UniversityThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Image created in 2014 by Tom

Updated on:May 20,2024

Researchers detect a loophole in chronic lymphocytic leukemia treatment

by Rockefeller University PressThe adhesive protein CD49d (red) is present on the surface of these adherent chronic lymphocytic leukemia cells. Credit: Tissino et al., 2018A team of researchers i

Updated on: March 01,2024

Researchers detect a loophole in chronic lymphocytic leukemia treatment

by Rockefeller University PressThe adhesive protein CD49d (red) is present on the surface of these adherent chronic lymphocytic leukemia cells. Credit: Tissino et al., 2018A team of researchers i

Updated on:March 01,2024

Study shows improved outcomes in hospitals accredited for rectal cancer surgery

byAmerican College of SurgeonsCredit: Pixabay/CC0 Public DomainHospitals accredited by the American College of Surgeons (ACS) National Accreditation Program for Rectal Cancer (NAPRC) demonstrate

Updated on: March 30,2024

Study shows improved outcomes in hospitals accredited for rectal cancer surgery

byAmerican College of SurgeonsCredit: Pixabay/CC0 Public DomainHospitals accredited by the American College of Surgeons (ACS) National Accreditation Program for Rectal Cancer (NAPRC) demonstrate

Updated on:March 30,2024

Researchers discover 40 genes involved in early development of myeloma

by Sarah Wells, The Institute of Cancer ResearchMicrograph of a plasmacytoma, the histologic correlate of multiple myeloma. H&E stain. Credit: Wikipedia/CC BY-SA 3.0Researchers have revealed 40 ge

Updated on: June 24,2024

Researchers discover 40 genes involved in early development of myeloma

by Sarah Wells, The Institute of Cancer ResearchMicrograph of a plasmacytoma, the histologic correlate of multiple myeloma. H&E stain. Credit: Wikipedia/CC BY-SA 3.0Researchers have revealed 40 ge

Updated on:June 24,2024

Without 'yoga and chardonnay' leukemia stem cells are stressed to death

by CU Anschutz Medical CampusCraig T. Jordan, Ph.D., and colleagues show that blocking the stress-relief of mitophagy kills leukemia stem cells without harming healthy blood stem cells. Credit: U

Updated on: March 01,2024

Without 'yoga and chardonnay' leukemia stem cells are stressed to death

by CU Anschutz Medical CampusCraig T. Jordan, Ph.D., and colleagues show that blocking the stress-relief of mitophagy kills leukemia stem cells without harming healthy blood stem cells. Credit: U

Updated on:March 01,2024

Study identifies new treatment target for metastatic cancer

by Elizabeth Chapin,University of KentuckySuccinate levels are elevated during EMT. (A) Expression of EMT markers was assessed by western blot in control, Snail1- and Twist1-expressing HMLE cell

Updated on: February 18,2024

Study identifies new treatment target for metastatic cancer

by Elizabeth Chapin,University of KentuckySuccinate levels are elevated during EMT. (A) Expression of EMT markers was assessed by western blot in control, Snail1- and Twist1-expressing HMLE cell

Updated on:February 18,2024

Researchers advance CRISPR technology to replicate human diseases with unprecedented accuracy

by Walter and Eliza Hall Institute of Medical ResearchGeneration and validation of pdCas9a-SAM construct in Eµ-Myc lymphoma cell lines. a Schematic representation of the pdCas9a-SAM lentiviral co

Updated on: February 03,2024

Researchers advance CRISPR technology to replicate human diseases with unprecedented accuracy

by Walter and Eliza Hall Institute of Medical ResearchGeneration and validation of pdCas9a-SAM construct in Eµ-Myc lymphoma cell lines. a Schematic representation of the pdCas9a-SAM lentiviral co

Updated on:February 03,2024

Insurance status mediates racial, ethnic inequities in cervical cancer, finds study

by Elana GotkineInsurance status mediates racial and ethnic inequities in advanced-stage cervical cancer diagnosis, according to a study published online March 10 inJAMA Network Open.Hunter K. H

Updated on: January 23,2024

Insurance status mediates racial, ethnic inequities in cervical cancer, finds study

by Elana GotkineInsurance status mediates racial and ethnic inequities in advanced-stage cervical cancer diagnosis, according to a study published online March 10 inJAMA Network Open.Hunter K. H

Updated on:January 23,2024

Sniffing out disease with smartphones

by CORDISCredit: CC0 Public DomainGastric cancer, also known as stomach cancer, is the fifth most common cause of cancer-related deaths in Europe. Because of the lack of early signs specifically

Updated on: May 09,2024

Sniffing out disease with smartphones

by CORDISCredit: CC0 Public DomainGastric cancer, also known as stomach cancer, is the fifth most common cause of cancer-related deaths in Europe. Because of the lack of early signs specifically

Updated on:May 09,2024

by Niigata UniversityCredit: Unsplash/CC0 Public DomainAn international team led by the Department of Neurosurgery, Niigata University, has identified a new gene called Schlafen11 (SLFN11) whose expre

Updated on: February 03,2024

by Niigata UniversityCredit: Unsplash/CC0 Public DomainAn international team led by the Department of Neurosurgery, Niigata University, has identified a new gene called Schlafen11 (SLFN11) whose expre

Updated on:February 03,2024