In the lab and in the clinic, alisertib with TAK-228 excels against solid tumors

by CU Anschutz Medical CampusUniversity of Colorado Cancer Center investigator, Jennifer Diamond, MD, and colleagues report promising phase I results of alisertib with TAK-228 against solid tumor

Updated on: April 22,2024

In the lab and in the clinic, alisertib with TAK-228 excels against solid tumors

by CU Anschutz Medical CampusUniversity of Colorado Cancer Center investigator, Jennifer Diamond, MD, and colleagues report promising phase I results of alisertib with TAK-228 against solid tumor

Updated on:April 22,2024

How a bereaved mom is helping researchers improve palliative care

by Erin Digitale,Stanford University Medical CenterJamila Hassan participated in research about end-of-life care for children after losing her son Omar to cancer in 2012. Credit: Courtesy of the

Updated on: January 04,2024

How a bereaved mom is helping researchers improve palliative care

by Erin Digitale,Stanford University Medical CenterJamila Hassan participated in research about end-of-life care for children after losing her son Omar to cancer in 2012. Credit: Courtesy of the

Updated on:January 04,2024

Hindering melanoma metastasis with an FDA-approved drug

by University of PennsylvaniaMelanoma in skin biopsy with H&E stain—this case may represent superficial spreading melanoma. Credit: Wikipedia/CC BY-SA 3.0For cancer to spread, it needs a hosp

Updated on: May 11,2024

Hindering melanoma metastasis with an FDA-approved drug

by University of PennsylvaniaMelanoma in skin biopsy with H&E stain—this case may represent superficial spreading melanoma. Credit: Wikipedia/CC BY-SA 3.0For cancer to spread, it needs a hosp

Updated on:May 11,2024

Selective nodal radiation may be a more effective approach in cancer treatment

byCU Anschutz Medical CampusENI ablates the immune response to combined radiation and immunotherapy. A Schematic of the experimental design for gross tumor irradiation with or without elective n

Updated on: January 15,2024

Selective nodal radiation may be a more effective approach in cancer treatment

byCU Anschutz Medical CampusENI ablates the immune response to combined radiation and immunotherapy. A Schematic of the experimental design for gross tumor irradiation with or without elective n

Updated on:January 15,2024

Researchers map the effects of dietary nutrients on disease

by The Francis Crick InstituteResearchers gathered experimental data to put into the model by measuring the levels of gene expression in liver and liver tumours from mice that had been fed either

Updated on: February 03,2024

Researchers map the effects of dietary nutrients on disease

by The Francis Crick InstituteResearchers gathered experimental data to put into the model by measuring the levels of gene expression in liver and liver tumours from mice that had been fed either

Updated on:February 03,2024

Neoadjuvant nivolumab shows long-term benefit in patients with non–small cell lung cancer

byAmerican Association for Cancer ResearchA–D, Kaplan–Meier curves depicting the recurrence-free survival (A) and overall survival (B) for patients who underwent definitive resection after recei

Updated on: January 13,2024

Neoadjuvant nivolumab shows long-term benefit in patients with non–small cell lung cancer

byAmerican Association for Cancer ResearchA–D, Kaplan–Meier curves depicting the recurrence-free survival (A) and overall survival (B) for patients who underwent definitive resection after recei

Updated on:January 13,2024

Identifying drug target candidates to treat pediatric rhabdomyosarcoma tumors

by Thamarasee Jeewandara , Medical XpressscRNAseq of RMS identifies heterogeneity recapitulating muscle developmental programs. (A) Experimental workflow. (B) UMAP plot of 48,859 RMS cells after regre

Updated on: January 02,2024

Identifying drug target candidates to treat pediatric rhabdomyosarcoma tumors

by Thamarasee Jeewandara , Medical XpressscRNAseq of RMS identifies heterogeneity recapitulating muscle developmental programs. (A) Experimental workflow. (B) UMAP plot of 48,859 RMS cells after regre

Updated on:January 02,2024

Designing an emergency stop switch for immunotherapies

by Ecole Polytechnique Federale de LausanneA mollecule allows for 'switching off' the therapy when a cancer patient's life is in danger. Credit: EPFLImmunotherapy, unlike chemotherapy

Updated on: March 09,2024

Designing an emergency stop switch for immunotherapies

by Ecole Polytechnique Federale de LausanneA mollecule allows for 'switching off' the therapy when a cancer patient's life is in danger. Credit: EPFLImmunotherapy, unlike chemotherapy

Updated on:March 09,2024

Cervical cancer discovery offers major new clue to better understand the disease

byUniversity College LondonDifferences in the tumor microenvironment between cervical cancer subgroups. Plot showing median abundances (x-axis) and median differences (%, y-axis) for different c

Updated on: January 22,2024

Cervical cancer discovery offers major new clue to better understand the disease

byUniversity College LondonDifferences in the tumor microenvironment between cervical cancer subgroups. Plot showing median abundances (x-axis) and median differences (%, y-axis) for different c

Updated on:January 22,2024

Regulation and potential drug targets of tumor-associated Tregs

by Science China PressRegulatory T cells (Tregs) negatively regulate the antitumour immune responses by inhibiting the function of effector T cells (CTL) and antigen presenting cells (APC). Credi

Updated on: April 07,2024

Regulation and potential drug targets of tumor-associated Tregs

by Science China PressRegulatory T cells (Tregs) negatively regulate the antitumour immune responses by inhibiting the function of effector T cells (CTL) and antigen presenting cells (APC). Credi

Updated on:April 07,2024

Geographical, racial/ethnic differences seen for triple-negative breast cancer

by Lori SolomonThere are substantial state variations in racial and ethnic disparities in triple-negative breast cancer (TNBC) incidence in the United States, according to a study published online Mar

Updated on: January 03,2024

Geographical, racial/ethnic differences seen for triple-negative breast cancer

by Lori SolomonThere are substantial state variations in racial and ethnic disparities in triple-negative breast cancer (TNBC) incidence in the United States, according to a study published online Mar

Updated on:January 03,2024

Lung cancer treatment shows promise in tumor models

by UTSouthwestern Medical Center6TdG induces double stranded breaks and apoptosis in mouse tumors. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-44861-8A molecule

Updated on: March 20,2024

Lung cancer treatment shows promise in tumor models

by UTSouthwestern Medical Center6TdG induces double stranded breaks and apoptosis in mouse tumors. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-44861-8A molecule

Updated on:March 20,2024