Efficient removal of abnormal myelin allows survival of nerve fibers targeted by adaptive immune cells

by Julius-Maximilians-Universität WürzburgElectronmicroscopic pictures of white matter axons in healthy control mice (top) and mice with different myelin gene defects. Axons that remain wrapped w

Updated on: May 11,2024

Efficient removal of abnormal myelin allows survival of nerve fibers targeted by adaptive immune cells

by Julius-Maximilians-Universität WürzburgElectronmicroscopic pictures of white matter axons in healthy control mice (top) and mice with different myelin gene defects. Axons that remain wrapped w

Updated on:May 11,2024

Study examines trends in esophageal cancer disparities over time

by Elana GotkineFrom 1999 to 2020, age-adjusted esophageal cancer mortality decreased among Black adults but stabilized among white adults, reducing the racial mortality gap, according to a study&nbsp

Updated on: August 27,2024

Study examines trends in esophageal cancer disparities over time

by Elana GotkineFrom 1999 to 2020, age-adjusted esophageal cancer mortality decreased among Black adults but stabilized among white adults, reducing the racial mortality gap, according to a study&nbsp

Updated on:August 27,2024

New computational tool identifies novel targets for cancer immunotherapy

byChildren's Hospital of PhiladelphiaIRIS: A big-data informed computational platform for discovering AS-derived cancer immunotherapy targets. Overall workflow of IRIS, computational modules

Updated on: January 12,2024

New computational tool identifies novel targets for cancer immunotherapy

byChildren's Hospital of PhiladelphiaIRIS: A big-data informed computational platform for discovering AS-derived cancer immunotherapy targets. Overall workflow of IRIS, computational modules

Updated on:January 12,2024

Crucial role of JUN protein in restraining liver cancer growth discovered

by Leibniz Institute on Aging – Fritz Lipmann Institute (FLI)Synopsis. Credit:The EMBO Journal(2024). DOI: 10.1038/s44318-024-00188-0A team of scientists led by Dr. Björn von Eyss has disc

Updated on: September 07,2024

Crucial role of JUN protein in restraining liver cancer growth discovered

by Leibniz Institute on Aging – Fritz Lipmann Institute (FLI)Synopsis. Credit:The EMBO Journal(2024). DOI: 10.1038/s44318-024-00188-0A team of scientists led by Dr. Björn von Eyss has disc

Updated on:September 07,2024

Some young cancer survivors face higher risk of premature heart failure

by Northwestern UniversityIncident Heart Failure Among YA Cancer Survivors (A) Comparison of history of anthracycline treatment vs none. (B) Stratified by young adult (YA) cancers commonly treate

Updated on: February 03,2024

Some young cancer survivors face higher risk of premature heart failure

by Northwestern UniversityIncident Heart Failure Among YA Cancer Survivors (A) Comparison of history of anthracycline treatment vs none. (B) Stratified by young adult (YA) cancers commonly treate

Updated on:February 03,2024

2023 cisplatin shortage tied to use of alternatives for head, neck cancer

by Lori SolomonThe 2023 cisplatin shortage led to a shift in utilization to alternative therapies for head and neck cancer (HNC), resulting in significant cost increases, according to a study presente

Updated on: October 18,2024

2023 cisplatin shortage tied to use of alternatives for head, neck cancer

by Lori SolomonThe 2023 cisplatin shortage led to a shift in utilization to alternative therapies for head and neck cancer (HNC), resulting in significant cost increases, according to a study presente

Updated on:October 18,2024

A CAR T cell therapy for advanced ovarian cancer developed

by City of Hope National Medical CenterMembrane-bound IL-12 engineered TAG72-CAR T cells induce higher IFNγ, T-cell expansion, and anti-tumor activity in vitro.a–cTumor cell killing o

Updated on: February 18,2024

A CAR T cell therapy for advanced ovarian cancer developed

by City of Hope National Medical CenterMembrane-bound IL-12 engineered TAG72-CAR T cells induce higher IFNγ, T-cell expansion, and anti-tumor activity in vitro.a–cTumor cell killing o

Updated on:February 18,2024

A new approach to targeting cancer cells

by University of California - RiversideThe Pellecchia lab at UC Riverside is working on an approach in which effective drugs can be obtained by appropriately designing molecules to contain an ary

Updated on: March 27,2024

A new approach to targeting cancer cells

by University of California - RiversideThe Pellecchia lab at UC Riverside is working on an approach in which effective drugs can be obtained by appropriately designing molecules to contain an ary

Updated on:March 27,2024

How melanoma cells escape oxidative stress to metastasize

byWeill Cornell Medical CollegeResearchers have discovered how some melanoma cells defend against oxidative stress and metastasize to new organs. The anatomy of metastatic melanoma cells picture

Updated on: November 11,2024

How melanoma cells escape oxidative stress to metastasize

byWeill Cornell Medical CollegeResearchers have discovered how some melanoma cells defend against oxidative stress and metastasize to new organs. The anatomy of metastatic melanoma cells picture

Updated on:November 11,2024

Researchers report on intrathoracic synovial sarcoma with BRAF V600E mutation

by Impact Journals LLC(A) Axial T2 MR shows a heterogeneous mass in the cardiophrenic space with evidence of anterior chest wall invasion and intercostal invasion. (B) Axial T2 MR shows 35 % of reduct

Updated on: January 30,2024

Researchers report on intrathoracic synovial sarcoma with BRAF V600E mutation

by Impact Journals LLC(A) Axial T2 MR shows a heterogeneous mass in the cardiophrenic space with evidence of anterior chest wall invasion and intercostal invasion. (B) Axial T2 MR shows 35 % of reduct

Updated on:January 30,2024

Automated bone scan index prognostic for prostate cancer

(HealthDay)—The automated Bone Scan Index (aBSI) is an independent prognostic imaging biomarker of overall survival (OS) in metastatic castration-resistant prostate cancer (mCRPC), according to a stud

Updated on: April 01,2024

Automated bone scan index prognostic for prostate cancer

(HealthDay)—The automated Bone Scan Index (aBSI) is an independent prognostic imaging biomarker of overall survival (OS) in metastatic castration-resistant prostate cancer (mCRPC), according to a stud

Updated on:April 01,2024

Study reveals insights into DDX41 protein's role in blood cancer pathogenesis

by JooHyeon Heo,Ulsan National Institute of Science and TechnologyA schematic image showing the impact of DDX41 mutations on MDS patients. Credit: Won Chan Hwang et al/Ulsan National Institute o

Updated on: April 28,2024

Study reveals insights into DDX41 protein's role in blood cancer pathogenesis

by JooHyeon Heo,Ulsan National Institute of Science and TechnologyA schematic image showing the impact of DDX41 mutations on MDS patients. Credit: Won Chan Hwang et al/Ulsan National Institute o

Updated on:April 28,2024