Mechanism identified for drug resistance in glioblastoma brain tumors

by Sarah Avery,Duke UniversityPro-tumor immune programming in the glioma microenvironment is CaMKK2 dependent. a Schematic depicting scRNA-seq experimental design. n = 4 WT and CaMKK2 KO mice ha

Updated on: January 02,2024

Mechanism identified for drug resistance in glioblastoma brain tumors

by Sarah Avery,Duke UniversityPro-tumor immune programming in the glioma microenvironment is CaMKK2 dependent. a Schematic depicting scRNA-seq experimental design. n = 4 WT and CaMKK2 KO mice ha

Updated on:January 02,2024

Pancreatic cancer: Less toxic, more enduring drug may improve therapy

by Columbia University Irving Medical CenterIn preclinical testing, an experimental drug for pancreatic cancer blocks the formation of microtubules in the cell, hindering growth. Microtubules are

Updated on: May 13,2024

Pancreatic cancer: Less toxic, more enduring drug may improve therapy

by Columbia University Irving Medical CenterIn preclinical testing, an experimental drug for pancreatic cancer blocks the formation of microtubules in the cell, hindering growth. Microtubules are

Updated on:May 13,2024

New therapy harnesses patients' blood cells to fight tumors

by Win Reynolds,Northwestern UniversityCredit: CC0 Public DomainAdoptive cell therapy (ACT) has become a promising immunotherapy tool to help treat advanced melanoma. The therapy, which harnesse

Updated on: January 15,2024

New therapy harnesses patients' blood cells to fight tumors

by Win Reynolds,Northwestern UniversityCredit: CC0 Public DomainAdoptive cell therapy (ACT) has become a promising immunotherapy tool to help treat advanced melanoma. The therapy, which harnesse

Updated on:January 15,2024

Nutritional cues regulate pancreatic tumor's 'cell drinking'

by Sanford Burnham Prebys Medical Discovery InstituteCosimo Commisso, Ph.D., assistant professor in Sanford Burnham Prebys' NCI-designated Cancer Center. Credit: Sanford Burnham PrebysDespera

Updated on: May 11,2024

Nutritional cues regulate pancreatic tumor's 'cell drinking'

by Sanford Burnham Prebys Medical Discovery InstituteCosimo Commisso, Ph.D., assistant professor in Sanford Burnham Prebys' NCI-designated Cancer Center. Credit: Sanford Burnham PrebysDespera

Updated on:May 11,2024

GI symptoms persist in older female colorectal cancer survivors, study finds

by Emily Caldwell,The Ohio State UniversityGI symptoms in CRC survivors (Prevalence, and severity). A. Prevalence of GI symptoms with mild (blue bar) and with moderate-to-severe symptoms (red ba

Updated on: January 23,2024

GI symptoms persist in older female colorectal cancer survivors, study finds

by Emily Caldwell,The Ohio State UniversityGI symptoms in CRC survivors (Prevalence, and severity). A. Prevalence of GI symptoms with mild (blue bar) and with moderate-to-severe symptoms (red ba

Updated on:January 23,2024

Research reveals potential targets for therapeutic development for glioblastoma

by Amy Richardson,University of Alabama at BirminghamGraphical abstract. Credit:JCI Insight(2022). DOI: 10.1172/jci.insight.148717The University of Alabama at Birmingham Marnix E. He

Updated on: February 03,2024

Research reveals potential targets for therapeutic development for glioblastoma

by Amy Richardson,University of Alabama at BirminghamGraphical abstract. Credit:JCI Insight(2022). DOI: 10.1172/jci.insight.148717The University of Alabama at Birmingham Marnix E. He

Updated on:February 03,2024

Understanding athletes with lymphoma

byMayo ClinicHodgkin lymphoma, nodular lymphocyte predominant (high-power view) Credit: Gabriel Caponetti, MD./Wikipedia/CC BY-SA 3.0One July evening, Allison Rosenthal, D.O., received a flurry

Updated on: September 30,2024

Understanding athletes with lymphoma

byMayo ClinicHodgkin lymphoma, nodular lymphocyte predominant (high-power view) Credit: Gabriel Caponetti, MD./Wikipedia/CC BY-SA 3.0One July evening, Allison Rosenthal, D.O., received a flurry

Updated on:September 30,2024

Researchers generate lab-grown human tissue model for food tube cancer

by Johns Hopkins University School of MedicineHuman gastroesophageal junction-derived organoid, modified by dual-knockout of key tumor suppressor genes (TP53/CDKN2A) using CRISPR/Cas9 gene editin

Updated on: February 03,2024

Researchers generate lab-grown human tissue model for food tube cancer

by Johns Hopkins University School of MedicineHuman gastroesophageal junction-derived organoid, modified by dual-knockout of key tumor suppressor genes (TP53/CDKN2A) using CRISPR/Cas9 gene editin

Updated on:February 03,2024

Researchers make major advance with cancer-killing antibody-drug conjugates

by Doug Bennett,University of FloridaCredit:Journal of Medicinal Chemistry(2023). DOI: 10.1021/acs.jmedchem.2c01771Building a new precision cancer treatment comes with no shortage of

Updated on: February 20,2024

Researchers make major advance with cancer-killing antibody-drug conjugates

by Doug Bennett,University of FloridaCredit:Journal of Medicinal Chemistry(2023). DOI: 10.1021/acs.jmedchem.2c01771Building a new precision cancer treatment comes with no shortage of

Updated on:February 20,2024

Night work may increase the risk of aggressive prostate cancer in offshore petroleum workers

by University of Oslo, Faculty of MedicineExposure-risk curve for a non-linear model of rollover shift work exposure, generated using restricted cubic splines with five knots (0.58, 3.82, 8.99, 14.98

Updated on: January 29,2024

Night work may increase the risk of aggressive prostate cancer in offshore petroleum workers

by University of Oslo, Faculty of MedicineExposure-risk curve for a non-linear model of rollover shift work exposure, generated using restricted cubic splines with five knots (0.58, 3.82, 8.99, 14.98

Updated on:January 29,2024

Discovery suggests which thyroid cancer patients may need more aggressive treatment

by Ross Neitz,University of AlbertaOncology professor and surgeon Todd McMullen (right) says the study will help surgeons determine which patients will benefit from less aggressive treatment and

Updated on: April 18,2024

Discovery suggests which thyroid cancer patients may need more aggressive treatment

by Ross Neitz,University of AlbertaOncology professor and surgeon Todd McMullen (right) says the study will help surgeons determine which patients will benefit from less aggressive treatment and

Updated on:April 18,2024

Researchers identify a subset of patients with early melanoma who face a very low risk of dying from the disease

by WileyMelanoma. Credit: Wikimedia Commons/National Cancer InstituteAlthough melanoma is the most serious type of skin cancer, most patients have high chances of surviving the disease. There is

Updated on: February 23,2024

Researchers identify a subset of patients with early melanoma who face a very low risk of dying from the disease

by WileyMelanoma. Credit: Wikimedia Commons/National Cancer InstituteAlthough melanoma is the most serious type of skin cancer, most patients have high chances of surviving the disease. There is

Updated on:February 23,2024