Skin cancer-related mutations higher in the UK than Singapore, new study shows

by Wellcome Trust Sanger InstituteA representation of protein-altering mutations in 1 square centimeter of skin from donors of the UK and Singapore. The UK square contains many more circles. Cred

Updated on: February 23,2024

Skin cancer-related mutations higher in the UK than Singapore, new study shows

by Wellcome Trust Sanger InstituteA representation of protein-altering mutations in 1 square centimeter of skin from donors of the UK and Singapore. The UK square contains many more circles. Cred

Updated on:February 23,2024

New cancer drug candidate targets immune system 'brakes'

by Sarah C.P. Williams,University of ChicagoDesign and synthesis of stapled alpha-helical peptides targeting FOXP3. (A) Human FOXP3 sequence. Residues F214–K263 represent the entirety of a helix

Updated on: January 12,2024

New cancer drug candidate targets immune system 'brakes'

by Sarah C.P. Williams,University of ChicagoDesign and synthesis of stapled alpha-helical peptides targeting FOXP3. (A) Human FOXP3 sequence. Residues F214–K263 represent the entirety of a helix

Updated on:January 12,2024

The hitchhiker's guide to defeating glioblastoma

by Brigham and Women's HospitalGlioblastoma (histology slide). Credit: Wikipedia/CC BY-SA 3.0In cancer therapeutics research, microRNAs—tiny strings of nucleotides that get churned out inside

Updated on: April 18,2024

The hitchhiker's guide to defeating glioblastoma

by Brigham and Women's HospitalGlioblastoma (histology slide). Credit: Wikipedia/CC BY-SA 3.0In cancer therapeutics research, microRNAs—tiny strings of nucleotides that get churned out inside

Updated on:April 18,2024

Researchers uncover potential biomarkers of positive response to immunotherapy

by Denise Heady,University of California, Los AngelesResponse to ICI or MAPKi therapy is associated with increased T cell infiltration and enhanced interferon gamma (IFNγ) pathway activity in th

Updated on: January 30,2024

Researchers uncover potential biomarkers of positive response to immunotherapy

by Denise Heady,University of California, Los AngelesResponse to ICI or MAPKi therapy is associated with increased T cell infiltration and enhanced interferon gamma (IFNγ) pathway activity in th

Updated on:January 30,2024

Novel bioassay predicts cancer patients' response to immunotherapy

byBen-Gurion University of the NegevIcAR response to fresh and fixed PDXs and generation of an IcAR score.(A) Schematic representation of the IcAR assay protocol. Following flow cytometry determ

Updated on: January 12,2024

Novel bioassay predicts cancer patients' response to immunotherapy

byBen-Gurion University of the NegevIcAR response to fresh and fixed PDXs and generation of an IcAR score.(A) Schematic representation of the IcAR assay protocol. Following flow cytometry determ

Updated on:January 12,2024

Genetic breast cancer study alters guidelines in Sweden

by Lund UniversityCredit: Pixabay/CC0 Public DomainBRCA1 and BRCA2 are well-known breast cancer genes associated with a significantly increased risk of hereditary breast and ovarian cancer. Howev

Updated on: February 01,2024

Genetic breast cancer study alters guidelines in Sweden

by Lund UniversityCredit: Pixabay/CC0 Public DomainBRCA1 and BRCA2 are well-known breast cancer genes associated with a significantly increased risk of hereditary breast and ovarian cancer. Howev

Updated on:February 01,2024

Potential melanoma target bypasses therapeutic resistance to immune checkpoint blockers

by Jeff Hansen,University of Alabama at BirminghamConstitutive activation of JAK1/2 in IFNγR1KOmelanoma cells. a Identification of a JAK1/2-centric network of activated protein tyrosine ki

Updated on: January 02,2024

Potential melanoma target bypasses therapeutic resistance to immune checkpoint blockers

by Jeff Hansen,University of Alabama at BirminghamConstitutive activation of JAK1/2 in IFNγR1KOmelanoma cells. a Identification of a JAK1/2-centric network of activated protein tyrosine ki

Updated on:January 02,2024

Improving health outcomes with a little help from our friends—and artificial intelligence

by Medical University of South CarolinaDr. Chanita Hughes-Halbert of the Medical University of South Carolina and Hollings Cancer Center studies social determinants of health and health dispariti

Updated on: April 22,2024

Improving health outcomes with a little help from our friends—and artificial intelligence

by Medical University of South CarolinaDr. Chanita Hughes-Halbert of the Medical University of South Carolina and Hollings Cancer Center studies social determinants of health and health dispariti

Updated on:April 22,2024

COVID-19 pandemic halted breast cancer screenings for many, finds study

by Andrew J. Yawn,Tulane UniversityCredit: Unsplash/CC0 Public DomainThe COVID-19 pandemic significantly disrupted routine medical checks for many.A new study from Tulane University has found th

Updated on: January 23,2024

COVID-19 pandemic halted breast cancer screenings for many, finds study

by Andrew J. Yawn,Tulane UniversityCredit: Unsplash/CC0 Public DomainThe COVID-19 pandemic significantly disrupted routine medical checks for many.A new study from Tulane University has found th

Updated on:January 23,2024

Researchers find effective drug combinations for glioblastoma in mice

by The Spanish National Cancer Research CentreTelomeres (red) in mouse embryonic fibroblasts; DNA damage (green) caused by ERK inhibition. ERK is an enzyme in the RAS pathway whose inhibition lea

Updated on: June 04,2024

Researchers find effective drug combinations for glioblastoma in mice

by The Spanish National Cancer Research CentreTelomeres (red) in mouse embryonic fibroblasts; DNA damage (green) caused by ERK inhibition. ERK is an enzyme in the RAS pathway whose inhibition lea

Updated on:June 04,2024

Opinion: The urgent need to secure the future of the 'post-pandemic child'

by Monash UniversityCredit: Unsplash/CC0 Public DomainIn 2028, it will be eight years since COVID-19 was first detected in Australia. Today's post-pandemic child will be a teenager, facing a

Updated on: May 11,2024

Opinion: The urgent need to secure the future of the 'post-pandemic child'

by Monash UniversityCredit: Unsplash/CC0 Public DomainIn 2028, it will be eight years since COVID-19 was first detected in Australia. Today's post-pandemic child will be a teenager, facing a

Updated on:May 11,2024

Predicting cancer versus autism risk in PTEN patients

by Cleveland ClinicIn a newly published study, a team of researchers led by Charis Eng, M.D., Ph.D., Chair of Cleveland Clinic's Genomic Medicine Institute, identified a metabolite that may p

Updated on: May 07,2024

Predicting cancer versus autism risk in PTEN patients

by Cleveland ClinicIn a newly published study, a team of researchers led by Charis Eng, M.D., Ph.D., Chair of Cleveland Clinic's Genomic Medicine Institute, identified a metabolite that may p

Updated on:May 07,2024