Researchers design 'prodrug' that targets cancer cells' big appetite for glutamine, leaving healthy cells unharmed

by Johns Hopkins University School of MedicineSchematic showing DRP-104's bio-activation to DON in tumor and bio-inactivation to an inert metabolite in GI tissues. Credit: Jennifer E. Fairman

Updated on: February 18,2024

Researchers design 'prodrug' that targets cancer cells' big appetite for glutamine, leaving healthy cells unharmed

by Johns Hopkins University School of MedicineSchematic showing DRP-104's bio-activation to DON in tumor and bio-inactivation to an inert metabolite in GI tissues. Credit: Jennifer E. Fairman

Updated on:February 18,2024

Investigational drug may combat brain tumors by targeting cancer cells' fat production

by Katie Marquedant,Massachusetts General HospitalCorrelation analysis between SCD expression and sensitivity to YTX-7739. (A) Immunoblot analysis (left) of SCD expression in YTX-7739-sensitive

Updated on: February 01,2024

Investigational drug may combat brain tumors by targeting cancer cells' fat production

by Katie Marquedant,Massachusetts General HospitalCorrelation analysis between SCD expression and sensitivity to YTX-7739. (A) Immunoblot analysis (left) of SCD expression in YTX-7739-sensitive

Updated on:February 01,2024

Trial finds high-dose radiation effective for men whose prostate cancer has spread

by American Society for Radiation OncologyCredit: ASTROA randomized clinical trial of targeted, high-dose radiation for men with oligometastatic prostate cancer has shown the treatment to be an e

Updated on: March 01,2024

Trial finds high-dose radiation effective for men whose prostate cancer has spread

by American Society for Radiation OncologyCredit: ASTROA randomized clinical trial of targeted, high-dose radiation for men with oligometastatic prostate cancer has shown the treatment to be an e

Updated on:March 01,2024

Biomarker test could improve diagnosis of endometrial cancer

by Mike Addelman,University of Manchester(a) Box plots showing the permutation importance of the plasma proteins confirmed by the Boruta algorithm to be important. (b) Crude cumulative AUC analy

Updated on: March 30,2024

Biomarker test could improve diagnosis of endometrial cancer

by Mike Addelman,University of Manchester(a) Box plots showing the permutation importance of the plasma proteins confirmed by the Boruta algorithm to be important. (b) Crude cumulative AUC analy

Updated on:March 30,2024

Researchers determine oral bacteria accelerate pancreatic cancer development in mice

by Hebrew University of JerusalemPancreas sections from control and P.gingivalis-infected mice. Control mouse showing a small pre-cancerous lesion (marked in yellow). Credit: Hebrew University of

Updated on: March 30,2024

Researchers determine oral bacteria accelerate pancreatic cancer development in mice

by Hebrew University of JerusalemPancreas sections from control and P.gingivalis-infected mice. Control mouse showing a small pre-cancerous lesion (marked in yellow). Credit: Hebrew University of

Updated on:March 30,2024

30-minute exercise session found to increase proportion of tumor-killing white blood cells in the bloodstream

byUniversity of TurkuExercise-induced changes in (A) total T cells, (B) CD4+helper T cells, (C) Th1 cells, (D) Th2 cells, (E) Th17 cells, (F) regulatory T cells, (G) CD8+cytotoxic T

Updated on: July 05,2024

30-minute exercise session found to increase proportion of tumor-killing white blood cells in the bloodstream

byUniversity of TurkuExercise-induced changes in (A) total T cells, (B) CD4+helper T cells, (C) Th1 cells, (D) Th2 cells, (E) Th17 cells, (F) regulatory T cells, (G) CD8+cytotoxic T

Updated on:July 05,2024

Asbestos study highlights risk of Australian Capital Territory residents developing cancer

byAustralian National UniversityCredit: Unsplash/CC0 Public DomainNew datapublishedin the latest edition of the ACT Asbestos Health Study, led by The Australian National University (

Updated on: September 30,2024

Asbestos study highlights risk of Australian Capital Territory residents developing cancer

byAustralian National UniversityCredit: Unsplash/CC0 Public DomainNew datapublishedin the latest edition of the ACT Asbestos Health Study, led by The Australian National University (

Updated on:September 30,2024

Clinicians, practices and patients all have a part to play in dealing with risks of remote GP consultations

by University of OxfordCredit: Unsplash/CC0 Public DomainWhile most remote GP consultations are safe, the "Remote by Default" study finds that GP consultations conducted remotely carry

Updated on: May 05,2024

Clinicians, practices and patients all have a part to play in dealing with risks of remote GP consultations

by University of OxfordCredit: Unsplash/CC0 Public DomainWhile most remote GP consultations are safe, the "Remote by Default" study finds that GP consultations conducted remotely carry

Updated on:May 05,2024

Self-testing cervical cancer screening could save Māori women's lives

by Victoria University of WellingtonElectron micrograph of a negatively stained human papilloma virus (HPV) which occurs in human warts. Credit: public domainCervical cancer is the second leading

Updated on: April 01,2024

Self-testing cervical cancer screening could save Māori women's lives

by Victoria University of WellingtonElectron micrograph of a negatively stained human papilloma virus (HPV) which occurs in human warts. Credit: public domainCervical cancer is the second leading

Updated on:April 01,2024

Early findings suggest clinical and lab-based approach critical to tracking head and neck cancer recurrence

by Anna Megdell,University of MichiganSurvival over time. (A)Median overall survival (mOS) plotted over years of the study. (B)mOS improved from 1998 to 2007 to 2008–2019. (C)m

Updated on: January 30,2024

Early findings suggest clinical and lab-based approach critical to tracking head and neck cancer recurrence

by Anna Megdell,University of MichiganSurvival over time. (A)Median overall survival (mOS) plotted over years of the study. (B)mOS improved from 1998 to 2007 to 2008–2019. (C)m

Updated on:January 30,2024

Novel biomarker found in ovarian cancer patients can predict response to therapy

by University of Chicago Medical CenterTumor-specific expression of CT45 stimulates the patient's immune system to fight the cancer and improves the efficacy of platinum-based chemotherapy. C

Updated on: April 23,2024

Novel biomarker found in ovarian cancer patients can predict response to therapy

by University of Chicago Medical CenterTumor-specific expression of CT45 stimulates the patient's immune system to fight the cancer and improves the efficacy of platinum-based chemotherapy. C

Updated on:April 23,2024

Researchers discuss HER2-low and HER2-zero in breast cancer

by Impact Journals LLCMicrograph showing a lymph node invaded by ductal breast carcinoma, with extension of the tumor beyond the lymph node. Credit: Nephron/WikipediaA new editorial paper titled &quot

Updated on: August 03,2024

Researchers discuss HER2-low and HER2-zero in breast cancer

by Impact Journals LLCMicrograph showing a lymph node invaded by ductal breast carcinoma, with extension of the tumor beyond the lymph node. Credit: Nephron/WikipediaA new editorial paper titled &quot

Updated on:August 03,2024