Researchers determine the structural basis for ApoE-Aβ interactions

by Boston University School of MedicineStructural model of apoE docked onto Aβ1–40fibril from AD vasculature. The model was obtained by using apoE segments shown in supplemental Fig. 2d–h a

Updated on: February 24,2024

Researchers determine the structural basis for ApoE-Aβ interactions

by Boston University School of MedicineStructural model of apoE docked onto Aβ1–40fibril from AD vasculature. The model was obtained by using apoE segments shown in supplemental Fig. 2d–h a

Updated on:February 24,2024

Cellular architecture of lesions in multiple sclerosis now mapped out

byKarolinska InstitutetCredit: Pixabay/CC0 Public DomainUsing advanced methodology, scientists in Sweden were able to reveal at the cellular level how lesions in multiple sclerosis develop. The

Updated on: March 27,2024

Cellular architecture of lesions in multiple sclerosis now mapped out

byKarolinska InstitutetCredit: Pixabay/CC0 Public DomainUsing advanced methodology, scientists in Sweden were able to reveal at the cellular level how lesions in multiple sclerosis develop. The

Updated on:March 27,2024

Clinical trial shows propranolol reduces tremors in Parkinson's disease

Clinical trial shows propranolol reduces tremors in Parkinson's diseasebyRadboud UniversityCerebral activity patterns measured by functional magnetic resonance imaging (fMRI). (A) shows the

Updated on: January 18,2025

Clinical trial shows propranolol reduces tremors in Parkinson's disease

Clinical trial shows propranolol reduces tremors in Parkinson's diseasebyRadboud UniversityCerebral activity patterns measured by functional magnetic resonance imaging (fMRI). (A) shows the

Updated on:January 18,2025

Researchers find possible neuromarker for 'juvenile-onset' Batten disease

by Kelsie Smith Hayduk,University of Rochester Medical CenterMeanMMN amplitude for each SOA in TD and CLN3 disease groups. Each scatter plot, box plot, and violin plot column represents in

Updated on: January 09,2024

Researchers find possible neuromarker for 'juvenile-onset' Batten disease

by Kelsie Smith Hayduk,University of Rochester Medical CenterMeanMMN amplitude for each SOA in TD and CLN3 disease groups. Each scatter plot, box plot, and violin plot column represents in

Updated on:January 09,2024

Combining the power of AI and the connectome to predict brain cell activity

byHoward Hughes Medical InstituteLight enters the compound eye of the fly, causing hexagonally arranged photoreceptors to send electrical signals through a complex neural network, enabling the f

Updated on: September 23,2024

Combining the power of AI and the connectome to predict brain cell activity

byHoward Hughes Medical InstituteLight enters the compound eye of the fly, causing hexagonally arranged photoreceptors to send electrical signals through a complex neural network, enabling the f

Updated on:September 23,2024

GOSH BRC Showcase 2025 - Genomic medicine

Updated on: November 06,2025

GOSH BRC Showcase 2025 - Genomic medicine

Updated on:November 06,2025

Newly found genetic variant defends against Alzheimer's disease

byColumbia University Irving Medical CenterCredit: Pixabay/CC0 Public DomainColumbia researchers have discovered a genetic variant that reduces the odds of developing Alzheimer's disease by

Updated on: April 27,2024

Newly found genetic variant defends against Alzheimer's disease

byColumbia University Irving Medical CenterCredit: Pixabay/CC0 Public DomainColumbia researchers have discovered a genetic variant that reduces the odds of developing Alzheimer's disease by

Updated on:April 27,2024

Discovery of early plasma biomarkers for Alzheimer's disease

by Institut national de la recherche scientifiqueINRS Professor Charles Ramassamy, specialist on Alzheimer's disease, doctoral student Mohamed Raâfet Ben Khedher and postdoctoral student Mohamed H

Updated on: May 28,2024

Discovery of early plasma biomarkers for Alzheimer's disease

by Institut national de la recherche scientifiqueINRS Professor Charles Ramassamy, specialist on Alzheimer's disease, doctoral student Mohamed Raâfet Ben Khedher and postdoctoral student Mohamed H

Updated on:May 28,2024

Very irregular sleep linked to higher risk of dementia

by American Academy of NeurologyCredit: Unsplash/CC0 Public DomainPeople who have very irregular sleep patterns may have a higher risk of dementia than those who have more regular sleep patterns,

Updated on: February 24,2024

Very irregular sleep linked to higher risk of dementia

by American Academy of NeurologyCredit: Unsplash/CC0 Public DomainPeople who have very irregular sleep patterns may have a higher risk of dementia than those who have more regular sleep patterns,

Updated on:February 24,2024

Scientists use an innovative approach to provide relevant insights into a rare neurologic disorder

by Germans Trias i Pujol Research InstituteLong-read nanopore sequencing of the genomic region including theDAB1ATTTT/ATTTC repeat tract enriched by CRISPR/Cas9.aThe integrativ

Updated on: March 20,2024

Scientists use an innovative approach to provide relevant insights into a rare neurologic disorder

by Germans Trias i Pujol Research InstituteLong-read nanopore sequencing of the genomic region including theDAB1ATTTT/ATTTC repeat tract enriched by CRISPR/Cas9.aThe integrativ

Updated on:March 20,2024

Zebrafish discovery could speed testing of motor neuron disease and dementia treatments

by Georgia Gowing,Macquarie UniversityCredit:Nucleic Acids Research(2024). DOI: 10.1093/nar/gkae112Tiny, transparent fish have made it possible for Macquarie University neuroscientis

Updated on: March 19,2024

Zebrafish discovery could speed testing of motor neuron disease and dementia treatments

by Georgia Gowing,Macquarie UniversityCredit:Nucleic Acids Research(2024). DOI: 10.1093/nar/gkae112Tiny, transparent fish have made it possible for Macquarie University neuroscientis

Updated on:March 19,2024

Daily learning test can detect Alzheimer's disease-related changes in memory among cognitively normal older adults

by Brigham and Women’s HospitalCapturing learning curves using the multiday Boston Remote Assessment for Neurocognitive Health. Credit:Annals of Neurology(2023). DOI: 10.1002/ana.2683

Updated on: February 24,2024

Daily learning test can detect Alzheimer's disease-related changes in memory among cognitively normal older adults

by Brigham and Women’s HospitalCapturing learning curves using the multiday Boston Remote Assessment for Neurocognitive Health. Credit:Annals of Neurology(2023). DOI: 10.1002/ana.2683

Updated on:February 24,2024