Clinical trial suggests new drug candidate for spinocerebellar ataxia may offer certain therapeutic benefits

byNiigata UniversityL-arginine inhibits the aggregation of polyglutamine proteins in neuronal cells. Credit: Niigata UniversityA team has conducted a trial on the efficacy and safety of L-argini

Updated on: December 18,2024

Clinical trial suggests new drug candidate for spinocerebellar ataxia may offer certain therapeutic benefits

byNiigata UniversityL-arginine inhibits the aggregation of polyglutamine proteins in neuronal cells. Credit: Niigata UniversityA team has conducted a trial on the efficacy and safety of L-argini

Updated on:December 18,2024

Scientists reveal structures of neurotransmitter transporter

bySt. Jude Children's Research HospitalCorresponding author Chia-Hsueh Lee, Ph.D., co-first author Shabareesh Pidathala, Ph.D., and co-first author Yaxin Dai, Ph.D. with maps of neurotransmi

Updated on: January 12,2024

Scientists reveal structures of neurotransmitter transporter

bySt. Jude Children's Research HospitalCorresponding author Chia-Hsueh Lee, Ph.D., co-first author Shabareesh Pidathala, Ph.D., and co-first author Yaxin Dai, Ph.D. with maps of neurotransmi

Updated on:January 12,2024

Pandemic adds to challenge of caring for loved one with dementia

by Amy NortonBefore the COVID-19 outbreak, Annette Adams-Brown's 87-year-old mother was an avid follower of TV news. Now Adams-Brown has to channel-surf for a less stressful pastime.Her mother, Be

Updated on: May 13,2024

Pandemic adds to challenge of caring for loved one with dementia

by Amy NortonBefore the COVID-19 outbreak, Annette Adams-Brown's 87-year-old mother was an avid follower of TV news. Now Adams-Brown has to channel-surf for a less stressful pastime.Her mother, Be

Updated on:May 13,2024

Cortexyme publishes data on P. gingivalis ability to infect neurons

by IOS PressP. gingivalisbacteria (arrows), after invading a neuron, causes damage to the cellular infrastructure and synapses. Credit: Cortexyme, Inc.Cortexyme, Inc., a clinical stage biop

Updated on: March 26,2024

Cortexyme publishes data on P. gingivalis ability to infect neurons

by IOS PressP. gingivalisbacteria (arrows), after invading a neuron, causes damage to the cellular infrastructure and synapses. Credit: Cortexyme, Inc.Cortexyme, Inc., a clinical stage biop

Updated on:March 26,2024

Patients with Alzheimer's dementia and related disorders who also have delirium incur greater health care costs

by Brigham and Women's HospitalCredit: Pixabay/CC0 Public DomainAlzheimer's Dementia and Related Disorders (ADRD) affects upwards of 5 million people in the United States, with no known t

Updated on: June 07,2024

Patients with Alzheimer's dementia and related disorders who also have delirium incur greater health care costs

by Brigham and Women's HospitalCredit: Pixabay/CC0 Public DomainAlzheimer's Dementia and Related Disorders (ADRD) affects upwards of 5 million people in the United States, with no known t

Updated on:June 07,2024

Molecular pathology of suicide: A postmortem study

byUniversity of AmsterdamCredit: Pixabay/CC0 Public DomainWhat changes in the brains of people who commit or think about committing suicide? Ph.D. candidate Lin Zhang investigated at a molecular

Updated on: January 12,2024

Molecular pathology of suicide: A postmortem study

byUniversity of AmsterdamCredit: Pixabay/CC0 Public DomainWhat changes in the brains of people who commit or think about committing suicide? Ph.D. candidate Lin Zhang investigated at a molecular

Updated on:January 12,2024

Blood-based marker for Alzheimer's disease shows diagnostic potential

by Alzheimer's Research UKDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.Researchers in Japan and Australia have used the ratio of different fo

Updated on: April 08,2024

Blood-based marker for Alzheimer's disease shows diagnostic potential

by Alzheimer's Research UKDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.Researchers in Japan and Australia have used the ratio of different fo

Updated on:April 08,2024

Alzheimer's disease risk gene APOE4 impairs function of brain immune cells

by University of Eastern FinlandThe induced pluripotent stem cell (iPSC) -derived microglia demonstrate that apolipoprotein E4 (APOE4) has a profound impact on several functions of human brain im

Updated on: April 08,2024

Alzheimer's disease risk gene APOE4 impairs function of brain immune cells

by University of Eastern FinlandThe induced pluripotent stem cell (iPSC) -derived microglia demonstrate that apolipoprotein E4 (APOE4) has a profound impact on several functions of human brain im

Updated on:April 08,2024

How the nervous system distinguishes between different types of social touch

byLinköping UniversityThe researchers at Linköping University study how the nervous system processes the social signals in touch, such as calming touch. Credit: Anna Nilsen/Linköping UniversityT

Updated on: December 16,2024

How the nervous system distinguishes between different types of social touch

byLinköping UniversityThe researchers at Linköping University study how the nervous system processes the social signals in touch, such as calming touch. Credit: Anna Nilsen/Linköping UniversityT

Updated on:December 16,2024

Study confirms cognitive deficits in people with the rare disease MOGAD

by Stefan Zorn, Medizinische Hochschule HannoverMean z-scores of neuropsychological tests at baseline (patients <60 years). PASAT, Paced Auditory Serial Addition Task; SDMT, Symbol Digit Modalities

Updated on: November 12,2024

Study confirms cognitive deficits in people with the rare disease MOGAD

by Stefan Zorn, Medizinische Hochschule HannoverMean z-scores of neuropsychological tests at baseline (patients <60 years). PASAT, Paced Auditory Serial Addition Task; SDMT, Symbol Digit Modalities

Updated on:November 12,2024

Lifestyle changes prevent cognitive decline even in genetically susceptible individuals

by University of Eastern FinlandEnhanced lifestyle counselling prevents cognitive decline even in people who are carriers of the APOE4 gene, a common risk factor of Alzheimer's disease, accor

Updated on: March 07,2024

Lifestyle changes prevent cognitive decline even in genetically susceptible individuals

by University of Eastern FinlandEnhanced lifestyle counselling prevents cognitive decline even in people who are carriers of the APOE4 gene, a common risk factor of Alzheimer's disease, accor

Updated on:March 07,2024

Consistent gene changes in Alzheimer's disease across studies

by Society for NeuroscienceTop 20 up and down-regulated genes for late phase Alzheimer's disease. Credit: Zhuang et al.,eNeuro2019A comparison of mouse Alzheimer's disease mod

Updated on: April 16,2024

Consistent gene changes in Alzheimer's disease across studies

by Society for NeuroscienceTop 20 up and down-regulated genes for late phase Alzheimer's disease. Credit: Zhuang et al.,eNeuro2019A comparison of mouse Alzheimer's disease mod

Updated on:April 16,2024