Sorting protein in neurons defends against neurodegenerative disease

by Temple UniversityDomenico Praticò, MD, Scott Richards North Star Foundation Chair for Alzheimer's Research, Professor in the Departments of Pharmacology and Microbiology, and Director of t

Updated on: May 26,2024

Sorting protein in neurons defends against neurodegenerative disease

by Temple UniversityDomenico Praticò, MD, Scott Richards North Star Foundation Chair for Alzheimer's Research, Professor in the Departments of Pharmacology and Microbiology, and Director of t

Updated on:May 26,2024

Protein aggregation: Protein assemblies relevant not only for neurodegenerative disease

by Heinrich-Heine University DuesseldorfCross section of the 3D model of an amyloid fibril against the backdrop of a cryo-electron microscopy recording. A PI3K SH3 domain is highlighted in yellow. Cre

Updated on: May 20,2024

Protein aggregation: Protein assemblies relevant not only for neurodegenerative disease

by Heinrich-Heine University DuesseldorfCross section of the 3D model of an amyloid fibril against the backdrop of a cryo-electron microscopy recording. A PI3K SH3 domain is highlighted in yellow. Cre

Updated on:May 20,2024

Extraction of bouton-like structures from neuropil calcium imaging data

by The University of Electro-CommunicationsCalcium imaging of the VNC neuropil in an isolated CNS. (A) Schematics of the CNS, the VNC, the neuropil, and boutons in the Drosophila larvae. (B) Schematic

Updated on: February 18,2024

Extraction of bouton-like structures from neuropil calcium imaging data

by The University of Electro-CommunicationsCalcium imaging of the VNC neuropil in an isolated CNS. (A) Schematics of the CNS, the VNC, the neuropil, and boutons in the Drosophila larvae. (B) Schematic

Updated on:February 18,2024

Specific brain responses to traumatic stress linked to PTSD risk

by University of North Carolina Health CareCredit: CC0 Public DomainResults from the largest prospective study of its kind indicate that in the initial days and weeks after experiencing trauma, i

Updated on: February 21,2024

Specific brain responses to traumatic stress linked to PTSD risk

by University of North Carolina Health CareCredit: CC0 Public DomainResults from the largest prospective study of its kind indicate that in the initial days and weeks after experiencing trauma, i

Updated on:February 21,2024

Improving the lives of people with dementia

by Cardiff UniversityCredit: CC0 Public DomainAn expert in the communication challenges caused by dementia is using her research to inform training practices for carers and families.Professor Ali

Updated on: June 04,2024

Improving the lives of people with dementia

by Cardiff UniversityCredit: CC0 Public DomainAn expert in the communication challenges caused by dementia is using her research to inform training practices for carers and families.Professor Ali

Updated on:June 04,2024

Dementia kills nearly three times more people than previously thought

by Boston University School of MedicineCredit: CC0 Public DomainDementia may be an underlying cause of nearly three times more deaths in the U.S. than official records show, according to a new Bo

Updated on: May 06,2024

Dementia kills nearly three times more people than previously thought

by Boston University School of MedicineCredit: CC0 Public DomainDementia may be an underlying cause of nearly three times more deaths in the U.S. than official records show, according to a new Bo

Updated on:May 06,2024

Nanoscopic motor proteins in the brain build the physical structures of memory, study finds

by Albert HiuKa Fok,The ConversationCredit:Cell Reports(2024). DOI: 10.1016/j.celrep.2024.113906The puzzle of memory has intrigued philosophers and intellects for a very long time. P

Updated on: July 06,2024

Nanoscopic motor proteins in the brain build the physical structures of memory, study finds

by Albert HiuKa Fok,The ConversationCredit:Cell Reports(2024). DOI: 10.1016/j.celrep.2024.113906The puzzle of memory has intrigued philosophers and intellects for a very long time. P

Updated on:July 06,2024

Lockdown and dementia: For some, COVID-19 has created an isolated, confusing but calmer world

by Catherine Talbot,The ConversationCredit: AI-generated imageThe approximately850,000people living with dementia in the UK have been badly affected by COVID-19. Many live in care ho

Updated on: June 01,2024

Lockdown and dementia: For some, COVID-19 has created an isolated, confusing but calmer world

by Catherine Talbot,The ConversationCredit: AI-generated imageThe approximately850,000people living with dementia in the UK have been badly affected by COVID-19. Many live in care ho

Updated on:June 01,2024

A new mechanism for crossing the blood–brain barrier

by Lori Dajose,California Institute of TechnologyCA-IV is required for the CNS potency of Car4-dependent AAV. (A) Immunostaining for CA-IV in the brains of WT/WT and KO/KO Car4 mice. Magnified r

Updated on: February 05,2024

A new mechanism for crossing the blood–brain barrier

by Lori Dajose,California Institute of TechnologyCA-IV is required for the CNS potency of Car4-dependent AAV. (A) Immunostaining for CA-IV in the brains of WT/WT and KO/KO Car4 mice. Magnified r

Updated on:February 05,2024

AI-based diagnostic tool differentiates dementia diseases by analysis of eye movement patterns

by University of TsukubaExamples of complex scene images with gaze densities derived from the CU, AD, and LBD groups. Results show that AD and LBD patients focused on fewer locations (A–D), had d

Updated on: June 15,2024

AI-based diagnostic tool differentiates dementia diseases by analysis of eye movement patterns

by University of TsukubaExamples of complex scene images with gaze densities derived from the CU, AD, and LBD groups. Results show that AD and LBD patients focused on fewer locations (A–D), had d

Updated on:June 15,2024

Low-cost versatile mesoscope makes brain imaging in rodents more accessible

by SPIEThis newly developed modular mesoscope can be used for in vivo fluorescence imaging of rodent brains. It is versatile and can adjust to different experimental requirements while still prov

Updated on: March 19,2024

Low-cost versatile mesoscope makes brain imaging in rodents more accessible

by SPIEThis newly developed modular mesoscope can be used for in vivo fluorescence imaging of rodent brains. It is versatile and can adjust to different experimental requirements while still prov

Updated on:March 19,2024

Different pain types in multiple sclerosis can cause difficulty staying active

by Valerie Goodwin,University of MichiganCredit: CC0 Public DomainFor patients with multiple sclerosis, a regular exercise routine is important for managing symptoms. But due to different causes

Updated on: January 11,2024

Different pain types in multiple sclerosis can cause difficulty staying active

by Valerie Goodwin,University of MichiganCredit: CC0 Public DomainFor patients with multiple sclerosis, a regular exercise routine is important for managing symptoms. But due to different causes

Updated on:January 11,2024