Degrading modified proteins could treat Alzheimer's, other 'undruggable' diseases

by American Chemical SocietyGraphical abstract. Credit:ACS Central Science(2023). DOI: 10.1021/acscentsci.2c01369Certain diseases, including Alzheimer's, are currently considered

Updated on: June 24,2024

Degrading modified proteins could treat Alzheimer's, other 'undruggable' diseases

by American Chemical SocietyGraphical abstract. Credit:ACS Central Science(2023). DOI: 10.1021/acscentsci.2c01369Certain diseases, including Alzheimer's, are currently considered

Updated on:June 24,2024

Study of older people shows lower risk of dementia with higher levels of apolipoprotein E in HDL

by Bob Yirka , Medical XpressA team of researchers affiliated with multiple institutions across the U.S. has found that older people who have heightened levels of apolipoprotein E in their high-densit

Updated on: March 07,2024

Study of older people shows lower risk of dementia with higher levels of apolipoprotein E in HDL

by Bob Yirka , Medical XpressA team of researchers affiliated with multiple institutions across the U.S. has found that older people who have heightened levels of apolipoprotein E in their high-densit

Updated on:March 07,2024

Dementia prevention strategies could save £1.9 billion annually

by University College LondonCredit: CC0 Public DomainPrograms to reduce dementia risk by targeting smoking, high blood pressure and hearing loss are likely to be cost-effective and cost saving by

Updated on: May 11,2024

Dementia prevention strategies could save £1.9 billion annually

by University College LondonCredit: CC0 Public DomainPrograms to reduce dementia risk by targeting smoking, high blood pressure and hearing loss are likely to be cost-effective and cost saving by

Updated on:May 11,2024

Dementia prevention study signs up first recruit

by University of EdinburghJulie Duffus from near Edinburgh, Scotland, is the first participant to enrol in a major dementia prevention study led by the University of Edinburgh. Credit: Maverick P

Updated on: May 11,2024

Dementia prevention study signs up first recruit

by University of EdinburghJulie Duffus from near Edinburgh, Scotland, is the first participant to enrol in a major dementia prevention study led by the University of Edinburgh. Credit: Maverick P

Updated on:May 11,2024

Genetic technique reverses Alzheimer's processes in mice

by Alzheimer's Research UKResearchers in the US have used genetic techniques to slow the progression of Alzheimer's in mice that show features of the disease. The study, which centered ar

Updated on: March 07,2024

Genetic technique reverses Alzheimer's processes in mice

by Alzheimer's Research UKResearchers in the US have used genetic techniques to slow the progression of Alzheimer's in mice that show features of the disease. The study, which centered ar

Updated on:March 07,2024

FDA approves much-debated Alzheimer's drug panned by experts

by Matthew PerroneIn this 2019 photo provided by Biogen, a researcher works on the development of the medication aducanumab in Cambridge, Mass. On Monday, June 7, 2021, the Food and Drug Administratio

Updated on: March 30,2024

FDA approves much-debated Alzheimer's drug panned by experts

by Matthew PerroneIn this 2019 photo provided by Biogen, a researcher works on the development of the medication aducanumab in Cambridge, Mass. On Monday, June 7, 2021, the Food and Drug Administratio

Updated on:March 30,2024

Dementia: how to prevent cognitive decline

by University of MontrealCredit: CC0 Public DomainPhysical activity, nutrition and cognitively stimulating activities are all known to be good ways to prevent Alzheimer's disease and dementia

Updated on: May 09,2024

Dementia: how to prevent cognitive decline

by University of MontrealCredit: CC0 Public DomainPhysical activity, nutrition and cognitively stimulating activities are all known to be good ways to prevent Alzheimer's disease and dementia

Updated on:May 09,2024

Neck scan could predict risk of developing cognitive decline

by Rowan Walker,University College LondonRed blood cells. Credit: PixabayA five-minute scan of blood vessels in the neck during mid-life could predict cognitive decline ten years before symptoms

Updated on: July 04,2024

Neck scan could predict risk of developing cognitive decline

by Rowan Walker,University College LondonRed blood cells. Credit: PixabayA five-minute scan of blood vessels in the neck during mid-life could predict cognitive decline ten years before symptoms

Updated on:July 04,2024

Hope for Alzheimer's blood test

by Macquarie UniversityBoxplots comparing plasma Aβ1-42/Aβ1-40 ratio, p-tau181, GFAP, and NfL between CU Aβ−, CU Aβ+, MCI Aβ−, MCI Aβ+, and AD Aβ+ groups at timepoint 1. Plasma measures were comp

Updated on: March 30,2024

Hope for Alzheimer's blood test

by Macquarie UniversityBoxplots comparing plasma Aβ1-42/Aβ1-40 ratio, p-tau181, GFAP, and NfL between CU Aβ−, CU Aβ+, MCI Aβ−, MCI Aβ+, and AD Aβ+ groups at timepoint 1. Plasma measures were comp

Updated on:March 30,2024

No reduction in death or severe brain injury with cerebral oximetry monitoring in extremely preterm infants, finds study

by Justin Jackson , Medical XpressCredit: Unsplash/CC0 Public DomainAn international team of 100 researchers at 70 sites in 17 countries has found no reduction in death for treatment guided by cerebra

Updated on: May 13,2024

No reduction in death or severe brain injury with cerebral oximetry monitoring in extremely preterm infants, finds study

by Justin Jackson , Medical XpressCredit: Unsplash/CC0 Public DomainAn international team of 100 researchers at 70 sites in 17 countries has found no reduction in death for treatment guided by cerebra

Updated on:May 13,2024

Parkinson's paradox: When more dopamine means more tremor

byChampalimaud Centre for the UnknownReduced dopamine loss is linked to tremor in Parkinson's patients, challenging common beliefs. Credit: Neural Circuits Dysfunction Lab, Champalimaud Foun

Updated on: November 27,2024

Parkinson's paradox: When more dopamine means more tremor

byChampalimaud Centre for the UnknownReduced dopamine loss is linked to tremor in Parkinson's patients, challenging common beliefs. Credit: Neural Circuits Dysfunction Lab, Champalimaud Foun

Updated on:November 27,2024

Alzheimer's and aducanumab: Unjust profits and false hopes

by The Hastings CenterCredit: CC0 Public DomainThe U.S. Food and Drug Administration's controversial decision to approve aducanumab for the treatment of Alzheimer's disease raises at leas

Updated on: April 08,2024

Alzheimer's and aducanumab: Unjust profits and false hopes

by The Hastings CenterCredit: CC0 Public DomainThe U.S. Food and Drug Administration's controversial decision to approve aducanumab for the treatment of Alzheimer's disease raises at leas

Updated on:April 08,2024