From autism to Alzheimer's: A large-scale animal study links brain pH changes to wide-ranging cognitive issues

byFujita Health UniversityIncreased brain lactate levels correlated with decreased pH are associated with poor working memory. Credit: eLife (2024). DOI: 10.7554/eLife.89376.3A global collaborat

Updated on: March 28,2024

From autism to Alzheimer's: A large-scale animal study links brain pH changes to wide-ranging cognitive issues

byFujita Health UniversityIncreased brain lactate levels correlated with decreased pH are associated with poor working memory. Credit: eLife (2024). DOI: 10.7554/eLife.89376.3A global collaborat

Updated on:March 28,2024

Waste management in the brain may shed light on dementia

by Jim Shelton,Yale UniversityFig. 1: CSF flow speed becomes hyperdynamic with severe CAA. Credit:Nature Aging(2022). DOI: 10.1038/s43587-022-00181-4A new study suggests that a contr

Updated on: May 18,2024

Waste management in the brain may shed light on dementia

by Jim Shelton,Yale UniversityFig. 1: CSF flow speed becomes hyperdynamic with severe CAA. Credit:Nature Aging(2022). DOI: 10.1038/s43587-022-00181-4A new study suggests that a contr

Updated on:May 18,2024

Do veterans who experience concussions have an increased risk of Alzheimer's?

by American Academy of NeurologyCredit: Pixabay/CC0 Public DomainMiddle-age veterans who experienced concussions due to blasts from explosive devices may have biomarkers in their spinal fluid sim

Updated on: March 19,2024

Do veterans who experience concussions have an increased risk of Alzheimer's?

by American Academy of NeurologyCredit: Pixabay/CC0 Public DomainMiddle-age veterans who experienced concussions due to blasts from explosive devices may have biomarkers in their spinal fluid sim

Updated on:March 19,2024

Shorter white blood cell telomeres linked to higher dementia risk

by British Medical JournalHuman chromosomes (grey) capped by telomeres (white). Credit: PD-NASA; PD-USGOV-NASAShorter telomeres on the ends of white blood cell chromosomes may signal a heightened

Updated on: March 02,2024

Shorter white blood cell telomeres linked to higher dementia risk

by British Medical JournalHuman chromosomes (grey) capped by telomeres (white). Credit: PD-NASA; PD-USGOV-NASAShorter telomeres on the ends of white blood cell chromosomes may signal a heightened

Updated on:March 02,2024

New tool provides researchers with improved understanding of stem cell aging in the brain

by University of Wisconsin-MadisonPatterns in the tiny amounts of light emitted by these neural stem cells helped researchers determine whether they were active or dormant without destructive tes

Updated on: March 30,2024

New tool provides researchers with improved understanding of stem cell aging in the brain

by University of Wisconsin-MadisonPatterns in the tiny amounts of light emitted by these neural stem cells helped researchers determine whether they were active or dormant without destructive tes

Updated on:March 30,2024

Llama nanobodies: New therapy can neutralize a wide variety of HIV-1 strains

by Noelle Toumey Reetz,Georgia State UniversityCryo-EM structures of nanobodies R27 and G36 in complex with HIV-1 Env trimer reveal modes of recognition similar to J3. Credit:Advanced Scie

Updated on: August 01,2024

Llama nanobodies: New therapy can neutralize a wide variety of HIV-1 strains

by Noelle Toumey Reetz,Georgia State UniversityCryo-EM structures of nanobodies R27 and G36 in complex with HIV-1 Env trimer reveal modes of recognition similar to J3. Credit:Advanced Scie

Updated on:August 01,2024

Loneliness associated with increased risk of dementia in older adults

by NYU Langone HealthChart showing incident of dementia for adults under age 80 without APOE ε4 allele, a genetic risk factor for Alzheimer's disease. Credit: NYU Langone HealthAs social isol

Updated on: June 05,2024

Loneliness associated with increased risk of dementia in older adults

by NYU Langone HealthChart showing incident of dementia for adults under age 80 without APOE ε4 allele, a genetic risk factor for Alzheimer's disease. Credit: NYU Langone HealthAs social isol

Updated on:June 05,2024

AAIC: Turnover kinetics vary for different amyloid beta isoforms

(HealthDay)—Amyloid beta (Aβ)38 has faster turnover kinetics than Aβ40 and Aβ42, according to a study published online July 19 inAlzheimer's & Dementiato coincide with presentation

Updated on: March 19,2024

AAIC: Turnover kinetics vary for different amyloid beta isoforms

(HealthDay)—Amyloid beta (Aβ)38 has faster turnover kinetics than Aβ40 and Aβ42, according to a study published online July 19 inAlzheimer's & Dementiato coincide with presentation

Updated on:March 19,2024

Sound stimulation aids saccular dysfunction with Meniere disease

by Lori Solomon and Marianne Madeiros sSound stimulation of 75 dB at a frequency of 100 Hz leads to improvement in cervical vestibular-evoked myogenic potential (cVEMP) amplitude in patients with defi

Updated on: July 05,2024

Sound stimulation aids saccular dysfunction with Meniere disease

by Lori Solomon and Marianne Madeiros sSound stimulation of 75 dB at a frequency of 100 Hz leads to improvement in cervical vestibular-evoked myogenic potential (cVEMP) amplitude in patients with defi

Updated on:July 05,2024

Protein shapes matter in Alzheimer's research

by Allison Mills,Michigan Technological UniversityCellular toxicity, which is higher in amyloid amorphous aggregates, shows that small changes in protein folding chemistry can cause differences

Updated on: April 16,2024

Protein shapes matter in Alzheimer's research

by Allison Mills,Michigan Technological UniversityCellular toxicity, which is higher in amyloid amorphous aggregates, shows that small changes in protein folding chemistry can cause differences

Updated on:April 16,2024

Understanding removal of brain fluid provides avenue for Alzheimer's treatment

by Alzheimer's Research UKResearchers in Switzerland have investigated the way fluid is removed from around the brain. Finding a new pathway for its removal, their work may signal a paradigm

Updated on: March 07,2024

Understanding removal of brain fluid provides avenue for Alzheimer's treatment

by Alzheimer's Research UKResearchers in Switzerland have investigated the way fluid is removed from around the brain. Finding a new pathway for its removal, their work may signal a paradigm

Updated on:March 07,2024

Most Medicare beneficiaries say they don't receive cognitive assessments

by Orli Belman,University of Southern CaliforniaCredit: CC0 Public DomainNew research from the University of Southern California measured the use of Medicaid's annual wellness visits and the

Updated on: May 13,2024

Most Medicare beneficiaries say they don't receive cognitive assessments

by Orli Belman,University of Southern CaliforniaCredit: CC0 Public DomainNew research from the University of Southern California measured the use of Medicaid's annual wellness visits and the

Updated on:May 13,2024