New study reveals how to rejuvenate the immune system of elderly people and reduce their risk of infectious disease

by University of California, IrvineResults from new study, led by Michael Demetriou, MD, PhD, may pave the way for new potential therapeutic targets to rejuvenate the immune system in older adult

Updated on: May 05,2024

New study reveals how to rejuvenate the immune system of elderly people and reduce their risk of infectious disease

by University of California, IrvineResults from new study, led by Michael Demetriou, MD, PhD, may pave the way for new potential therapeutic targets to rejuvenate the immune system in older adult

Updated on:May 05,2024

How chronic knee osteoarthritis pain affects cognitive function

by University of NottinghamCredit: CC0 Public DomainNew research suggests that chronic knee pain caused by osteoarthritis does not cause cognitive impairment in isolation, indicating that other f

Updated on: May 23,2024

How chronic knee osteoarthritis pain affects cognitive function

by University of NottinghamCredit: CC0 Public DomainNew research suggests that chronic knee pain caused by osteoarthritis does not cause cognitive impairment in isolation, indicating that other f

Updated on:May 23,2024

How one inflammatory disorder exacerbates another

by Katherine Unger Baillie,University of PennsylvaniaInflammation in the gums can increase susceptibility to other forms of inflammation, such as arthritis, through changes to immune cell precur

Updated on: March 25,2024

How one inflammatory disorder exacerbates another

by Katherine Unger Baillie,University of PennsylvaniaInflammation in the gums can increase susceptibility to other forms of inflammation, such as arthritis, through changes to immune cell precur

Updated on:March 25,2024

Team publishes findings about compound with potential for treating rheumatoid arthritis

by Montana State UniversityThis is a hand afflicted by rheumatoid arthritis. Credit: The University of ManchesterMontana State University researchers and their collaborators have published their

Updated on: April 20,2024

Team publishes findings about compound with potential for treating rheumatoid arthritis

by Montana State UniversityThis is a hand afflicted by rheumatoid arthritis. Credit: The University of ManchesterMontana State University researchers and their collaborators have published their

Updated on:April 20,2024

Moms with systemic lupus erythematosus at double the risk of having premature or growth-restricted babies, finds study

by British Medical JournalCredit: Unsplash/CC0 Public DomainMothers with the long term autoimmune disorder, systemic lupus erythematosus, or SLE for short, run more than double the risk of giving

Updated on: June 05,2024

Moms with systemic lupus erythematosus at double the risk of having premature or growth-restricted babies, finds study

by British Medical JournalCredit: Unsplash/CC0 Public DomainMothers with the long term autoimmune disorder, systemic lupus erythematosus, or SLE for short, run more than double the risk of giving

Updated on:June 05,2024

COVID-19's deadliness for men reveals why researchers should have been studying immune system sex differences years ago

by Adam Moeser,The ConversationCredit: CC0 Public DomainWhen it comes to surviving critical cases of COVID-19, it appears that men draw the short straw.Initial reports from China revealed the ea

Updated on: April 10,2024

COVID-19's deadliness for men reveals why researchers should have been studying immune system sex differences years ago

by Adam Moeser,The ConversationCredit: CC0 Public DomainWhen it comes to surviving critical cases of COVID-19, it appears that men draw the short straw.Initial reports from China revealed the ea

Updated on:April 10,2024

Frailty may be reversible for some people with rheumatoid arthritis

by University of GlasgowCredit: Unsplash/CC0 Public DomainRheumatoid arthritis patients living with frailty may find their frailty is reversible following treatment, according to a new study.The

Updated on: June 26,2024

Frailty may be reversible for some people with rheumatoid arthritis

by University of GlasgowCredit: Unsplash/CC0 Public DomainRheumatoid arthritis patients living with frailty may find their frailty is reversible following treatment, according to a new study.The

Updated on:June 26,2024

Immune system's moonlighters point the way to a new therapeutic target

FEBRUARY 20, 2024byCold Spring Harbor LaboratoryGraphical abstract. Credit:Molecular Cell(2024). DOI: 10.1016/j.molcel.2024.01.007Our immune system is remarkably powerful. It quickly

Updated on: March 25,2024

Immune system's moonlighters point the way to a new therapeutic target

FEBRUARY 20, 2024byCold Spring Harbor LaboratoryGraphical abstract. Credit:Molecular Cell(2024). DOI: 10.1016/j.molcel.2024.01.007Our immune system is remarkably powerful. It quickly

Updated on:March 25,2024

Three-dimensional label-free morphology of CD8+ T cells as a sepsis biomarker

by Chinese Academy of Sciencesa, Schematic overview of the study workflow. Blood was sampled three times in the sepsis recovery cohort and once in the healthy control cohort. CD8+ T cells were ex

Updated on: April 09,2024

Three-dimensional label-free morphology of CD8+ T cells as a sepsis biomarker

by Chinese Academy of Sciencesa, Schematic overview of the study workflow. Blood was sampled three times in the sepsis recovery cohort and once in the healthy control cohort. CD8+ T cells were ex

Updated on:April 09,2024

Combined inhibition of TNF-alpha, IL-17 effective in RA model

(HealthDay)—Combined inhibition of tumor necrosis factor (TNF) α and interleukin (IL)-17 is more effective than single blockade in cultures of human fibroblast-like synoviocytes (FLS), according to an

Updated on: April 08,2024

Combined inhibition of TNF-alpha, IL-17 effective in RA model

(HealthDay)—Combined inhibition of tumor necrosis factor (TNF) α and interleukin (IL)-17 is more effective than single blockade in cultures of human fibroblast-like synoviocytes (FLS), according to an

Updated on:April 08,2024

TET proteins regulate factors essential for normal antibody production

by La Jolla Institute for ImmunologyMutant B cells lacking TET2 and TET3 produce an overabundance of a class of antibody called IgM, whereas normal control B cells churned out more effective antibodie

Updated on: April 24,2024

TET proteins regulate factors essential for normal antibody production

by La Jolla Institute for ImmunologyMutant B cells lacking TET2 and TET3 produce an overabundance of a class of antibody called IgM, whereas normal control B cells churned out more effective antibodie

Updated on:April 24,2024

Loosening chimeric antigen receptor's grip on T-regulatory cells improves function, researchers find

by Leslie Cantu,Medical University of South CarolinaCAR and endogenous TCR/CD28 activation result in phenotypically similar Tregs. Credit:Molecular Therapy—Methods & Clinical Developme

Updated on: January 11,2025

Loosening chimeric antigen receptor's grip on T-regulatory cells improves function, researchers find

by Leslie Cantu,Medical University of South CarolinaCAR and endogenous TCR/CD28 activation result in phenotypically similar Tregs. Credit:Molecular Therapy—Methods & Clinical Developme

Updated on:January 11,2025