Leflunomide considered safe, effective for psoriatic arthritis

Leflunomide is effective for the treatment of patients with psoriatic arthritis in daily clinical practice, according to a study published online Oct. 6 inArthritis Care & Research.(HealthDa

Updated on: April 08,2024

Leflunomide considered safe, effective for psoriatic arthritis

Leflunomide is effective for the treatment of patients with psoriatic arthritis in daily clinical practice, according to a study published online Oct. 6 inArthritis Care & Research.(HealthDa

Updated on:April 08,2024

SARS-CoV-2 antibodies detectable up to seven months post COVID-19 onset

by Instituto de Medicina MolecularColorized scanning electron micrograph of a dying cell (blue) heavily infected with SARS-CoV-2 (yellow), the virus that causes COVID-19. Credit: NIAID Integrated Rese

Updated on: April 10,2024

SARS-CoV-2 antibodies detectable up to seven months post COVID-19 onset

by Instituto de Medicina MolecularColorized scanning electron micrograph of a dying cell (blue) heavily infected with SARS-CoV-2 (yellow), the virus that causes COVID-19. Credit: NIAID Integrated Rese

Updated on:April 10,2024

Study shows genetically modified pluripotent stem cells may evade immunological rejection after transplantation

by University of ArizonaGeneration of an HLA-I/II and MICA/B-deficient hESC line (A) Representation of the Cas9 editing strategy. Wild-type H1 hESCs were transfected with a Cas9 construct and up

Updated on: March 07,2024

Study shows genetically modified pluripotent stem cells may evade immunological rejection after transplantation

by University of ArizonaGeneration of an HLA-I/II and MICA/B-deficient hESC line (A) Representation of the Cas9 editing strategy. Wild-type H1 hESCs were transfected with a Cas9 construct and up

Updated on:March 07,2024

Team explores role of 'stimulator of interferon genes' in body's innate immune system

by Tokai National Higher Education and Research SystemA graphical illustration of cholesterol- and palmitoylation-dependent STING clustering at the TGN. Credit: Institute for Glyco-core ResearchWhen p

Updated on: June 18,2024

Team explores role of 'stimulator of interferon genes' in body's innate immune system

by Tokai National Higher Education and Research SystemA graphical illustration of cholesterol- and palmitoylation-dependent STING clustering at the TGN. Credit: Institute for Glyco-core ResearchWhen p

Updated on:June 18,2024

Immune system's moonlighters point the way to a new therapeutic target

FEBRUARY 20, 2024byCold Spring Harbor LaboratoryGraphical abstract. Credit:Molecular Cell(2024). DOI: 10.1016/j.molcel.2024.01.007Our immune system is remarkably powerful. It quickly

Updated on: March 25,2024

Immune system's moonlighters point the way to a new therapeutic target

FEBRUARY 20, 2024byCold Spring Harbor LaboratoryGraphical abstract. Credit:Molecular Cell(2024). DOI: 10.1016/j.molcel.2024.01.007Our immune system is remarkably powerful. It quickly

Updated on:March 25,2024

Sex-specific immune response in COVID-19 linked to cellular metabolism

by Rick Harrison,Yale UniversityImage of the ultrastructural morphology exhibited by the 2019 Novel Coronavirus (2019-nCoV). Credit: CDCResearchers studying COVID-19 patients have found a metabo

Updated on: April 13,2024

Sex-specific immune response in COVID-19 linked to cellular metabolism

by Rick Harrison,Yale UniversityImage of the ultrastructural morphology exhibited by the 2019 Novel Coronavirus (2019-nCoV). Credit: CDCResearchers studying COVID-19 patients have found a metabo

Updated on:April 13,2024

How one inflammatory disorder exacerbates another

by Katherine Unger Baillie,University of PennsylvaniaInflammation in the gums can increase susceptibility to other forms of inflammation, such as arthritis, through changes to immune cell precur

Updated on: March 25,2024

How one inflammatory disorder exacerbates another

by Katherine Unger Baillie,University of PennsylvaniaInflammation in the gums can increase susceptibility to other forms of inflammation, such as arthritis, through changes to immune cell precur

Updated on:March 25,2024

COVID-19 : Measuring viral RNA to predict which patients will die

by University of MontrealColorized scanning electron micrograph of a cell (blue) heavily infected with SARS-CoV-2 virus particles (red), isolated from a patient sample. Image captured at the NIAI

Updated on: April 10,2024

COVID-19 : Measuring viral RNA to predict which patients will die

by University of MontrealColorized scanning electron micrograph of a cell (blue) heavily infected with SARS-CoV-2 virus particles (red), isolated from a patient sample. Image captured at the NIAI

Updated on:April 10,2024

Moms with systemic lupus erythematosus at double the risk of having premature or growth-restricted babies, finds study

by British Medical JournalCredit: Unsplash/CC0 Public DomainMothers with the long term autoimmune disorder, systemic lupus erythematosus, or SLE for short, run more than double the risk of giving

Updated on: June 05,2024

Moms with systemic lupus erythematosus at double the risk of having premature or growth-restricted babies, finds study

by British Medical JournalCredit: Unsplash/CC0 Public DomainMothers with the long term autoimmune disorder, systemic lupus erythematosus, or SLE for short, run more than double the risk of giving

Updated on:June 05,2024

Study shows autoantibodies behind lifelong risk of viral infection

byUniversity of ZurichCredit: CC0 Public DomainA new study,publishedin theJournal of Experimental Medicine, shows that about 2% of the population develop autoantibodies against

Updated on: July 30,2024

Study shows autoantibodies behind lifelong risk of viral infection

byUniversity of ZurichCredit: CC0 Public DomainA new study,publishedin theJournal of Experimental Medicine, shows that about 2% of the population develop autoantibodies against

Updated on:July 30,2024

Using molecular scissors to improve CAR-T cell therapy

by Susan Buckles,Mayo ClinicAn in vitro model for chronic stimulation induces phenotypic and functional signs of exhaustion in CART19-28ζ cells. Credit:Nature Communications(2024). D

Updated on: September 18,2024

Using molecular scissors to improve CAR-T cell therapy

by Susan Buckles,Mayo ClinicAn in vitro model for chronic stimulation induces phenotypic and functional signs of exhaustion in CART19-28ζ cells. Credit:Nature Communications(2024). D

Updated on:September 18,2024

How chronic knee osteoarthritis pain affects cognitive function

by University of NottinghamCredit: CC0 Public DomainNew research suggests that chronic knee pain caused by osteoarthritis does not cause cognitive impairment in isolation, indicating that other f

Updated on: May 23,2024

How chronic knee osteoarthritis pain affects cognitive function

by University of NottinghamCredit: CC0 Public DomainNew research suggests that chronic knee pain caused by osteoarthritis does not cause cognitive impairment in isolation, indicating that other f

Updated on:May 23,2024