Optimizing boosters: How COVID mRNA vaccines reshape immune memory after each dose

by Tokyo University of ScienceChanges in the clonal populations of CD8+T- cells after successive vaccinations, an ability that can be tuned for developing more effective mRNA vaccines. Cred

Updated on: March 19,2024

Optimizing boosters: How COVID mRNA vaccines reshape immune memory after each dose

by Tokyo University of ScienceChanges in the clonal populations of CD8+T- cells after successive vaccinations, an ability that can be tuned for developing more effective mRNA vaccines. Cred

Updated on:March 19,2024

Indoor allergens worsen respiratory infections in children with asthma, study finds

byUniversity of Texas at AustinCredit: Andrea Piacquadio from PexelsChildren with asthma who are exposed to high levels of indoor allergens, such as cockroach and mouse allergens, are at an incr

Updated on: September 18,2024

Indoor allergens worsen respiratory infections in children with asthma, study finds

byUniversity of Texas at AustinCredit: Andrea Piacquadio from PexelsChildren with asthma who are exposed to high levels of indoor allergens, such as cockroach and mouse allergens, are at an incr

Updated on:September 18,2024

A novel animal model for analysing human natural killer cell functions in vivo

by Kawasaki CityFigure 1: Humanized mice were generated by transplanting 2.5 x 104 human cord blood-derived CD34+ HSC cells into irradiated NOG-IL-2 mice. After human CD34+ cell transplantation, human

Updated on: March 25,2024

A novel animal model for analysing human natural killer cell functions in vivo

by Kawasaki CityFigure 1: Humanized mice were generated by transplanting 2.5 x 104 human cord blood-derived CD34+ HSC cells into irradiated NOG-IL-2 mice. After human CD34+ cell transplantation, human

Updated on:March 25,2024

Improving uniformity and quality of care for people undergoing intra-articular injection

by EULARCredit: CC0 Public DomainIntra-articular therapies (IAT) are frequently used to treat joint conditions such as gout, rheumatoid arthritis, or osteoarthritis. The procedure involves inserting a

Updated on: May 29,2024

Improving uniformity and quality of care for people undergoing intra-articular injection

by EULARCredit: CC0 Public DomainIntra-articular therapies (IAT) are frequently used to treat joint conditions such as gout, rheumatoid arthritis, or osteoarthritis. The procedure involves inserting a

Updated on:May 29,2024

Study advances understanding of liver immune response in cirrhosis

byMiguel Hernandez University of ElcheLSECtin expression in the liver inversely correlates with Th17 expansion in cirrhosis. (A) Representative Immunohistochemistry of the lymphocyte-specific tr

Updated on: April 28,2024

Study advances understanding of liver immune response in cirrhosis

byMiguel Hernandez University of ElcheLSECtin expression in the liver inversely correlates with Th17 expansion in cirrhosis. (A) Representative Immunohistochemistry of the lymphocyte-specific tr

Updated on:April 28,2024

Repurposing tocilizumab in scleroderma patients may prevent early lung disease

by Jordyn Imhoff,University of MichiganCredit: CC0 Public DomainResearch led by Michigan Medicine's Scleroderma Program and published in Arthritis & Rheumatology found that tocilizumab,

Updated on: April 07,2024

Repurposing tocilizumab in scleroderma patients may prevent early lung disease

by Jordyn Imhoff,University of MichiganCredit: CC0 Public DomainResearch led by Michigan Medicine's Scleroderma Program and published in Arthritis & Rheumatology found that tocilizumab,

Updated on:April 07,2024

COVID-19 virus rapidly evolves to higher infectivity during in vitro growth, which may be a step toward lower virulence

by Jeff Hansen,University of Alabama at BirminghamCredit: Pixabay/CC0 Public DomainViruses accumulate mutations as they replicate in infected cells. Repeated replication can lead to viral strain

Updated on: April 10,2024

COVID-19 virus rapidly evolves to higher infectivity during in vitro growth, which may be a step toward lower virulence

by Jeff Hansen,University of Alabama at BirminghamCredit: Pixabay/CC0 Public DomainViruses accumulate mutations as they replicate in infected cells. Repeated replication can lead to viral strain

Updated on:April 10,2024

Urine of COVID-19 patients could predict who will develop severe disease

by American Physiological SocietyCredit: Unsplash/CC0 Public DomainUrine analysis of COVID-19 patients revealed elevated levels of specific biomarkers of the immune system compared to those who w

Updated on: April 10,2024

Urine of COVID-19 patients could predict who will develop severe disease

by American Physiological SocietyCredit: Unsplash/CC0 Public DomainUrine analysis of COVID-19 patients revealed elevated levels of specific biomarkers of the immune system compared to those who w

Updated on:April 10,2024

New algorithm may greatly speed up the design of 'humanized' antibodies that work

by Weizmann Institute of Science3D structure of an antibody’s “finger,” the portion that binds to a target. The colored regions are responsible for recognizing the target; the gray regions provid

Updated on: March 07,2024

New algorithm may greatly speed up the design of 'humanized' antibodies that work

by Weizmann Institute of Science3D structure of an antibody’s “finger,” the portion that binds to a target. The colored regions are responsible for recognizing the target; the gray regions provid

Updated on:March 07,2024

Key protein linked to immune disorders

by Hokkaido UniversityThe inflammatory reaction in spinal cords of STAP-1 knockout (KO) mice was less severe than that of wild type (WT) mice (top panels). In parallel, spinal cords of STAP-1 KO

Updated on: March 19,2024

Key protein linked to immune disorders

by Hokkaido UniversityThe inflammatory reaction in spinal cords of STAP-1 knockout (KO) mice was less severe than that of wild type (WT) mice (top panels). In parallel, spinal cords of STAP-1 KO

Updated on:March 19,2024

Moms with lupus more likely to have children with autism, study suggests

by Serena Gordon, Healthday ReporterBut overall risk is low, shouldn't influence parenting decisions, expert says.(HealthDay)—Women with lupus are twice as likely to have a child with autism compa

Updated on: March 24,2024

Moms with lupus more likely to have children with autism, study suggests

by Serena Gordon, Healthday ReporterBut overall risk is low, shouldn't influence parenting decisions, expert says.(HealthDay)—Women with lupus are twice as likely to have a child with autism compa

Updated on:March 24,2024

An infamous 'inflammasome'—a rogue protein complex—appears to underlie a rare and disabling autoimmune disorder

by Delthia Ricks , Medical XpressCa2+ influx is required for PIEZO-dependent NLRP3 inflammasome activation. Credit:Science Immunology(2023). DOI: 10.1126/sciimmunol.adf4699Autoimmune disea

Updated on: March 30,2024

An infamous 'inflammasome'—a rogue protein complex—appears to underlie a rare and disabling autoimmune disorder

by Delthia Ricks , Medical XpressCa2+ influx is required for PIEZO-dependent NLRP3 inflammasome activation. Credit:Science Immunology(2023). DOI: 10.1126/sciimmunol.adf4699Autoimmune disea

Updated on:March 30,2024