ATP from sensory neuron-interneuron crosstalk is key to spreading inflammation in rheumatoid arthritis

by Hokkaido UniversityThe inflammation signal (IL-6 amplifier) in the affected joint (L) causes the secretion of ATP that transmits a signal through the spinal cord (DRG, L5), which in turn trigg

Updated on: June 06,2024

ATP from sensory neuron-interneuron crosstalk is key to spreading inflammation in rheumatoid arthritis

by Hokkaido UniversityThe inflammation signal (IL-6 amplifier) in the affected joint (L) causes the secretion of ATP that transmits a signal through the spinal cord (DRG, L5), which in turn trigg

Updated on:June 06,2024

Successful murine model of dermatomyositis reveals underlying immune system involvement

byTokyo Medical and Dental UniversityAutoimmunity to MDA5, CD4 T cells reactive MDA5, works as 'Seed', and inducible factors like as virus infection and poly (I:C) treatment induce type

Updated on: April 28,2024

Successful murine model of dermatomyositis reveals underlying immune system involvement

byTokyo Medical and Dental UniversityAutoimmunity to MDA5, CD4 T cells reactive MDA5, works as 'Seed', and inducible factors like as virus infection and poly (I:C) treatment induce type

Updated on:April 28,2024

How a pregnant woman who smokes can be hurting her future grandchildren

by Ileana Varela,Florida International UniversityCredit: CC0 Public DomainThe dangers of smoking are common knowledge. Smoking during pregnancy, even second-hand smoke, can hurt both the mother

Updated on: April 24,2024

How a pregnant woman who smokes can be hurting her future grandchildren

by Ileana Varela,Florida International UniversityCredit: CC0 Public DomainThe dangers of smoking are common knowledge. Smoking during pregnancy, even second-hand smoke, can hurt both the mother

Updated on:April 24,2024

First-degree relatives have high perceived risk for rheumatoid arthritis

by Elana GotkineFirst-degree relatives (FDRs) of patients with rheumatoid arthritis (RA) have a high perceived risk for developing RA, according to a study published online Dec. 5 inRMD Open.Sar

Updated on: June 26,2024

First-degree relatives have high perceived risk for rheumatoid arthritis

by Elana GotkineFirst-degree relatives (FDRs) of patients with rheumatoid arthritis (RA) have a high perceived risk for developing RA, according to a study published online Dec. 5 inRMD Open.Sar

Updated on:June 26,2024

Hope for treating autoimmune diseases: Researchers explore diagnostic role of the systemic inflammation index

by Flinders UniversityCredit: Unsplash/CC0 Public DomainA routine blood test that measures a patient's inflammation levels could improve the early diagnosis and management of a wide range of

Updated on: April 06,2024

Hope for treating autoimmune diseases: Researchers explore diagnostic role of the systemic inflammation index

by Flinders UniversityCredit: Unsplash/CC0 Public DomainA routine blood test that measures a patient's inflammation levels could improve the early diagnosis and management of a wide range of

Updated on:April 06,2024

S1P molecule regulates dendritic cell localization and vascular integrity in lymph nodes

by Osaka UniversityCredit: Osaka UniversityThe trafficking of white blood cells called lymphocytes is crucial for controlling our immune response. Maintaining the integrity of high endothelial ve

Updated on: April 22,2024

S1P molecule regulates dendritic cell localization and vascular integrity in lymph nodes

by Osaka UniversityCredit: Osaka UniversityThe trafficking of white blood cells called lymphocytes is crucial for controlling our immune response. Maintaining the integrity of high endothelial ve

Updated on:April 22,2024

Trial shows timing matters when adding immunotherapy to chemoradiation for limited-stage small cell lung cancer

byAmerican Society for Radiation OncologyCredit: Pixabay/CC0 Public DomainPeople with limited-stage small cell lung cancer may benefit from adding immunotherapy to chemoradiation, but not if bot

Updated on: October 26,2024

Trial shows timing matters when adding immunotherapy to chemoradiation for limited-stage small cell lung cancer

byAmerican Society for Radiation OncologyCredit: Pixabay/CC0 Public DomainPeople with limited-stage small cell lung cancer may benefit from adding immunotherapy to chemoradiation, but not if bot

Updated on:October 26,2024

Teens with chronic conditions face challenges and risks when they age out of pediatric rheumatology care

by Michelle Batthish and Stephanie Garner,The ConversationCredit: AI-generated imageLiving with severeinflammatory arthritisor any other serious condition of the joints, bones and mu

Updated on: May 19,2024

Teens with chronic conditions face challenges and risks when they age out of pediatric rheumatology care

by Michelle Batthish and Stephanie Garner,The ConversationCredit: AI-generated imageLiving with severeinflammatory arthritisor any other serious condition of the joints, bones and mu

Updated on:May 19,2024

An extra X chromosome-linked gene may explain decreased viral infection severity in females

by University of California, Los AngelesCredit: CC0 Public DomainIt has long been known that viral infections can be more severe in males than females, but the question as to why has remained a m

Updated on: April 24,2024

An extra X chromosome-linked gene may explain decreased viral infection severity in females

by University of California, Los AngelesCredit: CC0 Public DomainIt has long been known that viral infections can be more severe in males than females, but the question as to why has remained a m

Updated on:April 24,2024

Non-surgical treatment significantly reduces knee pain for adults, especially those 50 and older

by The Reis GroupCredit: Pixabay/CC0 Public DomainGenicular nerve radiofrequency ablation is a minimally invasive treatment for knee pain due to osteoarthritis of the knee, and can significantly reduc

Updated on: May 23,2024

Non-surgical treatment significantly reduces knee pain for adults, especially those 50 and older

by The Reis GroupCredit: Pixabay/CC0 Public DomainGenicular nerve radiofrequency ablation is a minimally invasive treatment for knee pain due to osteoarthritis of the knee, and can significantly reduc

Updated on:May 23,2024

Finger length a 'pointer' to Osteoarthritis

by Monash University(Medical Xpress)—Our fingers could be more important than we think. New research has revealed that the length of a person's finger could become a 'pointer' to thei

Updated on: March 24,2024

Finger length a 'pointer' to Osteoarthritis

by Monash University(Medical Xpress)—Our fingers could be more important than we think. New research has revealed that the length of a person's finger could become a 'pointer' to thei

Updated on:March 24,2024

Does alcohol consumption have an effect on arthritis?

by WileyCredit: CC0 Public DomainSeveral previous studies have demonstrated that moderate alcohol consumption is linked with less severe disease and better quality of life in patients with rheuma

Updated on: April 07,2024

Does alcohol consumption have an effect on arthritis?

by WileyCredit: CC0 Public DomainSeveral previous studies have demonstrated that moderate alcohol consumption is linked with less severe disease and better quality of life in patients with rheuma

Updated on:April 07,2024